PA1-20205 detects MDC1 in human samples.
PA1-20205 has been successfully used in immunofluorescence and Western blot procedures.
The PA1-20205 immunogen is a synthetic peptide corresponding to residues 1883-2089 of human MDC1.
MDC1 participates in the early response to DNA damage. It is thought to be a member of the BRCT (BRCA1 C-terminus) super family of nuclear proteins. It contains an N-terminus forkhead-associated (FHA) motif, two C-terminus BRCT motifs and 13 internal repetitions of a 41 amino acid sequence.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: DAAP-285E11.7; DKFZp781A0122; homologue to Drosophila photoreceptor protein calphotin; KIAA0170; Mediator of DNA damage checkpoint protein 1; mediator of DNA-damage checkpoint 1; MGC166888; NFBD1; Nuclear factor with BRCT domains 1
Gene Aliases: KIAA0170; MDC1; NFBD1
UniProt ID: (Human) Q14676
Entrez Gene ID: (Human) 9656