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|Tested species reactivity||Human|
|Host / Isotype||Sheep / IgG|
|Immunogen||Synthetic peptide corresponding to residues 1883-2089 of human MDC1.|
|Storage buffer||whole serum|
|Contains||0.09% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:2000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA1-20205 detects MDC1 in human samples.
PA1-20205 has been successfully used in immunofluorescence and Western blot procedures.
The PA1-20205 immunogen is a synthetic peptide corresponding to residues 1883-2089 of human MDC1.
MDC1 participates in the early response to DNA damage. It is thought to be a member of the BRCT (BRCA1 C-terminus) super family of nuclear proteins. It contains an N-terminus forkhead-associated (FHA) motif, two C-terminus BRCT motifs and 13 internal repetitions of a 41 amino acid sequence.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
DAAP-285E11.7; DKFZp781A0122; homologue to Drosophila photoreceptor protein calphotin; KIAA0170; mediator of DNA-damage checkpoint 1; MGC166888; NFBD1; nuclear factor with BRCT domains 1
KIAA0170; MDC1; NFBD1