Suggested positive control: Jurkat whole cell lysate.
NFBD1, nuclear factor with BRCT domains protein 1, participates in the early response to DNA damage. It is thought to be a member of the BRCT (BRCA1 C-terminus) superfamily of nuclear proteins. It contains an N-terminus forkhead-associated (FHA) motif, two C-terminus BRCT motifs and 13 internal repetitions of a 41 amino acid sequence. A more recent renaming of NFBD1 is MDC1 (mediator of DNA damage checkpoint protein).
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Protein Aliases: DAAP-285E11.7; DKFZp781A0122; homologue to Drosophila photoreceptor protein calphotin; KIAA0170; Mediator of DNA damage checkpoint protein 1; mediator of DNA-damage checkpoint 1; MGC166888; NFBD1; Nuclear factor with BRCT domains 1
Gene Aliases: KIAA0170; MDC1; NFBD1
UniProt ID: (Human) Q14676
Entrez Gene ID: (Human) 9656