Immunogen sequence: IPKYPTNPPG QLPSPPHVPS YWHPSRRIQG SLRDPEFQHN VGKARMNNLQ LPQHEAFNDE DEDRLSEISA RSAASSLRAF QTLARAKKRK EN
Highest antigen sequence identity to the following orthologs: Mouse - 73%, Rat - 74%.
This gene encodes a nuclear protein similar to the mouse double minute 1 protein. The mouse gene is located in double minute (DM) chromatin particles, is amplified in the mouse transformed 3T3 cell line, and the encoded protein is able to bind to p53. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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Protein Aliases: Mdm1 nuclear protein homolog; Mdm4, transformed 3T3 cell double minute 1, p53 binding protein; nuclear protein double minute 1; Nuclear protein MDM1
Gene Aliases: MDM1
UniProt ID: (Human) Q8TC05
Entrez Gene ID: (Human) 56890