Recommended positive controls: A549, HeLa, HepG2, HCT116.
Predicted reactivity: Mouse (97%), Rat (98%), Bovine (95%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Zinc, an essential element required for cell proliferation and differentiation, plays a role in a diverse array of cellular functions, including acting as a cofactor for numerous enzymes and transcription factors and as a neuroregulator. The zinc transporter (ZnT) family regulates the supply of zinc within cells, and its members are characterized by containing six membrane-spanning domains, a large histidine-rich intracellular loop, and a C-terminal tail. ZnT-1, a ubiquitous protein of approximately 60 kDa, localizes to the plasma membrane to aid in the export of zinc out of cells.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: FLJ20045; mediator 18; Mediator complex subunit 18; Mediator of RNA polymerase II transcription subunit 18; mediator of RNA polymerase II transcription, subunit 18 homolog; p28b; TRAP/mediator complex subunit p28b
Gene Aliases: MED18; p28b
UniProt ID: (Human) Q9BUE0
Entrez Gene ID: (Human) 54797