PA5-30757 targets MED18 in IF, IHC (P), and WB applications and shows reactivity with Human samples.
The PA5-30757 immunogen is recombinant fragment corresponding to a region within amino acids 1 and 208 of Human MED18.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.
MED18 is a component of the Mediator complex, which is a coactivator for DNA-binding factors that activate transcription via RNA polymerase II (Sato et al., 2003 [PubMed 12584197]).
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Protein Aliases: Mediator complex subunit 18; mediator of RNA polymerase II transcription; Mediator of RNA polymerase II transcription subunit 18; mediator of RNA polymerase II transcription, subunit 18 homolog; p28b; subunit 18 homolog; TRAP/mediator complex subunit p28b
Gene Aliases: MED18; p28b
UniProt ID: (Human) Q9BUE0
Entrez Gene ID: (Human) 54797