Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
FIGURE: 1 / 2
Positive test controls include: Raji, Mouse brain, Mouse spinal cord.
Immunogen sequence: SGAQTPGAHH FMSEYLKQEE STRQGARQLH VLVPQSPPTD LPGLTREVTQ DDLDRIQASQ WPGVNGCQDT QGNWY
This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone.
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For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Activator-recruited cofactor 70 kDa component; ARC70; Cofactor required for Sp1 transcriptional activation subunit 7; cofactor required for Sp1 transcriptional activation, subunit 7 (70kD); cofactor required for Sp1 transcriptional activation, subunit 7, 70kDa; CRSP complex subunit 7; Mediator complex subunit 26; Mediator of RNA polymerase II transcription subunit 26; solute carrier family 35, member E1; Transcriptional coactivator CRSP70
Gene Aliases: 5730493L18Rik; AI414941; ARC70; AW495270; CRSP7; CRSP70; MED26; Slc35e1
UniProt ID: (Human) O95402, (Mouse) Q7TN02
Entrez Gene ID: (Human) 9441, (Mouse) 70625, (Rat) 306328
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