Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Keep as concentrated solution.
Predicted reactivity: Mouse (96%), Rat (97%), Zebrafish (87%), Xenopus laevis (87%), Pig (97%), Chicken (90%), Rhesus Monkey (100%), Bovine (96%).
Positive Control: A549.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Cofactor required for Sp1 transcriptional activation subunit 8; cofactor required for Sp1 transcriptional activation, subunit 8, 34kDa; CRSP complex subunit 8; Mediator complex subunit 27; Mediator of RNA polymerase II transcription subunit 27; MGC11274; P37 TRAP/SMCC/PC2 subunit; Transcriptional coactivator CRSP34
Gene Aliases: CRAP34; CRSP34; CRSP8; MED27; MED3; TRAP37
UniProt ID: (Human) Q6P2C8
Entrez Gene ID: (Human) 9442
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