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Proteintech
MED30 Polyclonal Antibody
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Product Details
16787-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
MED30 Fusion Protein Ag10221 (1-178 aa encoded by BC008226)
Conjugate
Form
Liquid
Concentration
0.13 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MSTPPLAAS GMAPGPFAGP QAQQAAREVN TASLCRIGQE TVQDIVYRTM EIFQLLRNMQ LPNGVTYHTG TYQDRLTKLQ DNLRQLSVLF RKLRLVYDKC NENCGGMDPI PVEQLIPYVE EDGSKNDDRA GPPRFASEER REIAEVNKKL KQKNQQLKQI MDQLRNLIWD INAMLAMRN (1-178 aa encoded by BC008226 )
Target Information
Med30 is a subunit of the RNA polymerase II (Pol II) transcriptional mediator complex. The mediator complex is a coactivator involved in the regulated transcription of Pol II-dependent genes. The mediator complex functions as a bridge to convey information from gene-specific regulatory proteins to the basal Pol II transcription machinery, and is recruited to promoter regions by directly interacting with regulatory proteins. The mediator complex also serves as a scaffold for the assembly of a functional pre-initiation complex with Pol II and other general transcription factors. Found in the nucleus, Med30 is expressed in brain, heart, kidney, liver, lung, pancreas, placenta and skeletal muscle.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Mediator complex subunit 30; Mediator of RNA polymerase II transcription subunit 30; putative mediator of RNA polymerase II transcription subunit 30; thyroid hormone receptor associated protein 6; Thyroid hormone receptor-associated protein 6; Thyroid hormone receptor-associated protein complex 25 kDa component; TRAP/Mediator complex component TRAP25; Trap25
Gene Aliases: 1810038N03Rik; 2510044J04Rik; MED30; MED30S; THRAP6; TRAP25
UniProt ID: (Human) Q96HR3, (Mouse) Q9CQI9
Entrez Gene ID: (Human) 90390, (Mouse) 69790
RNA polymerase II transcription cofactor activity
transcription cofactor activity
receptor activity
protein binding
ligand-dependent nuclear receptor transcription coactivator activity
vitamin D receptor binding
thyroid hormone receptor binding
ubiquitin protein ligase activity
general transcription factor
regulation of transcription from RNA polymerase II promoter
transcription initiation from RNA polymerase II promoter
protein ubiquitination
stem cell population maintenance
intracellular steroid hormone receptor signaling pathway
androgen receptor signaling pathway
positive regulation of transcription, DNA-templated
transcription, DNA-templated
regulation of transcription, DNA-templated
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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