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Proteintech
MED6 Polyclonal Antibody
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Product Details
15338-1-AP
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
MED6 Fusion Protein Ag7541 (1-246 aa encoded by BC004106)
Conjugate
Form
Liquid
Concentration
0.15 mg/mL
Amount
22.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MAAVDIRDN LLGISWVDSS WIPILNSGSV LDYFSERSNP FYDRTCNNEV VKMQRLTLEH LNQMVGIEYI LLHAQEPILF IIRKQQRQSP AQVIPLADYY IIAGVIYQAP DLGSVINSRV LTAVHGIQSA FDEAMSYCRY HPSKGYWWHF KDHEEQDKVR PKAKRKEEPS SIFQRQRVDA LLLDLRQKFP PKFVQLKPGE KPVPVDQTKK EAEPIPETVK PEEKETTKNV QQTVSAKGPP EKRMRLQ (1-246 aa encoded by BC004106)
Target Information
MED6 is a component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. And mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Activator-recruited cofactor 33 kDa component; ARC33; CTD-2540L5.5; hMed6; MED6; Mediator complex subunit 6; Mediator of RNA polymerase II transcription subunit 6; mediator of RNA polymerase II transcription, subunit 6 homolog; Renal carcinoma antigen NY-REN-28; unnamed protein product
Gene Aliases: 1500012F11Rik; ARC33; AU019660; AV213303; MED6; NY-REN-28
UniProt ID: (Human) O75586, (Mouse) Q921D4
Entrez Gene ID: (Human) 10001, (Rat) 299180, (Mouse) 69792
regulation of transcription from RNA polymerase II promoter
protein ubiquitination
positive regulation of transcription elongation from RNA polymerase II promoter
somatic stem cell population maintenance
positive regulation of transcription from RNA polymerase II promoter
RNA polymerase II transcriptional preinitiation complex assembly
positive regulation of transcription initiation from RNA polymerase II promoter
transcription from RNA polymerase II promoter
stem cell population maintenance
transcription, DNA-templated
regulation of transcription, DNA-templated
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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