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Proteintech
MED8 Polyclonal Antibody
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Product Details
12182-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
MED8 Fusion Protein Ag2827 (86-297 aa encoded by BC010543)
Conjugate
Form
Liquid
Concentration
0.57 mg/mL
Amount
85.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MRQTEGRVP VFSHEVVPDH LRTKPDPEVE EQEKQLTTDA ARIGADAAQK QIQSLNKMCS NLLEKISKEE RESESGGLRP NKQTFNPTDT NALVAAVAFG KGLSNWRPSG SSGPGQAGQP GAGTILAGTS GLQQVQMAGA PSQQQPMLSG VQMAQAGQPG KMPSGIKTNI KSASMHPYQR PSCLGFILAI PLRRKVKKLL GQEGKKNAHL QLW (86-297 aa encoded by BC010543)
Target Information
This gene encodes a protein that is one of more than 20 subunits of the mediator complex, first identified in S. cerevisiae, that is required for activation of transcription. The product of this gene also interacts with elongins B and C, and CUL2 and RBX1, to reconstitute a ubiquitin ligase. Two alternative transcripts encoding different isoforms have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Activator-recruited cofactor 32 kDa component; ARC32; Mediator complex subunit 8; Mediator of RNA polymerase II transcription subunit 8; mediator of RNA polymerase II transcription subunit MED8; mediator of RNA polymerase II transcription, subunit 8 homolog; MGC17544; MGC19641; mMED8
Gene Aliases: 2210021A15Rik; AB041805; ARC32; MED8; MNCb-2386
UniProt ID: (Human) Q96G25, (Mouse) Q9D7W5
Entrez Gene ID: (Human) 112950, (Mouse) 80509
regulation of transcription from RNA polymerase II promoter
protein ubiquitination
positive regulation of transcription elongation from RNA polymerase II promoter
RNA polymerase II transcriptional preinitiation complex assembly
positive regulation of transcription initiation from RNA polymerase II promoter
transcription, DNA-templated
regulation of transcription, DNA-templated
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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