Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Peptide sequence: MQREEKQLEA SLDALLSQVA DLKNSLGSFI CKLENEYGRL TWPSVLDSFA
Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 86%
This gene encodes a protein that is one of more than 20 subunits of the mediator complex, first identified in S. cerevisiae, that is required for activation of transcription. The product of this gene also interacts with elongins B and C, and CUL2 and RBX1, to reconstitute a ubiquitin ligase. Two alternative transcripts encoding different isoforms have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Activator-recruited cofactor 32 kDa component; ARC32; Mediator complex subunit 8; Mediator of RNA polymerase II transcription subunit 8; mediator of RNA polymerase II transcription subunit MED8; MGC17544; MGC19641
Gene Aliases: ARC32; MED8
UniProt ID: (Human) Q96G25
Entrez Gene ID: (Human) 112950
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