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Abnova
MEF2B Polyclonal Antibody, MaxPab™
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FIGURE: 1 / 1
MEF2B Antibody (H00004207-D01P) in WB
Western Blot analysis of MEF2B expression in transfected 293T cell line (H00004207-T02) by MEF2B MaxPab polyclonal antibody.
Lane 1: MEF2B transfected lysate(38.60 KDa).
Lane 2: Non-transfected lysate.
Lane 1: MEF2B transfected lysate(38.60 KDa).
Lane 2: Non-transfected lysate.
Product Details
H00004207-D01P
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
MEF2B (NP_005910.1, 1 a.a. approximately 365 a.a) full-length human protein.
Conjugate
Form
Liquid
Concentration
See Label
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Sequence of this protein is as follows: MGRKKIQISR ILDQRNRQVT FTKRKFGLMK KAYELSVLCD CEIALIIFNS ANRLFQYAST DMDRVLLKYT EYSEPHESRT NTDILETLKR RGIGLDGPEL EPDEGPEEPG EKFRRLAGEG GDPALPRPRL YPAAPAMPSP DVVYGALPPP GCDPSGLGEA LPAQSRPSPF RPAAPKAGPP GLVHPLFSPS HLTSKTPPPL YLPTEGRRSD LPGGLAGPRG GLNTSRSLYS GLQNPCSTAT PGPPLGSFPF LPGGPPVGAE AWARRVPQPA APPRRPPQSA SSLSASLRPP GAPATFLRPS PIPCSSPGPW QSLCGLGPPC AGCPWPTAGP GRRSPGGTSP ERSPGTARAR GDPTSLQASS EKTQQ
Target Information
The myocyte enhancer factor-2 (MEF-2) family of transcription factors associated with co-repessors or co-activators to regulate development and function of T cells, neuronal cells and muscle cells. Four family members arise from alternatively spliced transcripts, termed MEF-2A, -2B, -2C and -2D. These members bind as homo- and heterodimers to the MEF-2 site in the promoter region of affected genes. Differential regulation in the expression of the four transcripts implies functional distinction for each during embryogenesis and development. The process of differentiation from mesodermal precursor cells to myoblasts has led to the discovery of a variety of tissue-specific factors that regulate muscle gene expression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: LOC729991-MEF2B; MADS box transcription enhancer factor 2, polypeptide B (myocyte enhancer factor 2B); MEF2BNB-MEF2B; Myocyte-specific enhancer factor 2B; RSRFR2; Serum response factor-like protein 2
Gene Aliases: MEF2B; RSRFR2; XMEF2
UniProt ID: (Human) Q02080
Entrez Gene ID: (Human) 100271849
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcription factor activity, sequence-specific DNA binding
histone deacetylase binding
protein dimerization activity
MADS box transcription factor
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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