PA5-28247 targets MEF2C in IHC (P) and WB applications and shows reactivity with Human samples.
The PA5-28247 immunogen is recombinant protein fragment corresponding to a region within amino acids 1 and 320 of Human MEF2C.
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This locus encodes a member of the MADS box transcription enhancer factor 2 (MEF2) family of proteins, which play a role in myogenesis. The encoded protein, MEF2 polypeptide C, has both trans-activating and DNA binding activities. This protein may play a role in maintaining the differentiated state of muscle cells. Mutations and deletions at this locus have been associated with severe mental retardation, stereotypic movements, epilepsy, and cerebral malformation. Alternatively spliced transcript variants have been described.
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Protein Aliases: C5DELq14.3; DEL5q14.3, MADS box transcription enhancer factor 2, polypeptide C, myocyte-specific enhancer factor 2C; MADS box transcription enhancer factor 2, polypeptide C; Myocyte enhancer factor 2C; Myocyte-specific enhancer factor 2C
Gene Aliases: 5430401D19Rik; 9930028G15Rik; AV011172; C5DELq14.3; DEL5q14.3; Mef2; MEF2C