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|Tested species reactivity||Dog, Chicken, Horse, Human, Mouse, Rat, Xenopus|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide (296 THPYPSEEQKKQLAQD 311) of MEIS1 protein.|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS with 0.05% BSA|
|Contains||0.05% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||5 µg/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
MEIS1, also known as Homeobox protein Meis1, is a nuclear protein belonging to the TALE/MEIS homeobox family with a homeobox DNA-binding domain. It acts as a transcriptional regulator of PAX6 (Paired box protein Pax-6). It is a protein required for hematopoiesis, megakaryocyte lineage development and vascular patterning. Expression is seen at low levels in normal immunohepatopoietic tissues, and in a subset of myeloid leukemia cell lines, with the highest expression seen in those with a megakaryocytic-erythroid phenotype. It is also expressed at high levels in the cerebellum.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
homeobox protein Meis1; leukemogenic homolog protein; Meis1; Meis1, myeloid ecotropic viral integration site 1 homolog; myeloid ecotropic viral insertion site-1a protein; myeloid ecotropic viral integration site 1; myeloid ecotropic viral integration site 1 homolog; WUGSC:H_NH0444B04.1; XMeis1; XMeis1-2 protein
C530044H18Rik; Evi8; MEIS1