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Product Details
PA5-30956
Product Specifications
Species Reactivity
Human,
Mouse,
Zebrafish
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein fragment corresponding to a region within amino acids 27 and 381 of Human MEIS2
Conjugate
Form
Liquid
Concentration
0.74 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
0.1M tris glycine, pH 7, with 20% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2548430
Product Specific Information
Recommended positive controls: NT2D1, U87-MG, JC, zebrafish brain, zebrafish liver.
Predicted reactivity: Mouse (100%), Rat (100%), Chicken (99%), Bovine (99%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
This gene encodes a homeobox protein belonging to the TALE family of homeodomain-containing proteins. TALE homeobox proteins are highly conserved transcription regulators, and several members have been shown to be essential contributors to developmental programs. Multiple transcript variants encoding distinct isoforms have been described for this gene.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 2; Homeobox protein Meis2; Meis homolog 2; Meis1, myeloid ecotropic viral integration site 1 homolog 2; Meis1-related gene 1; Meis1-related protein 1; Meis2 homeobox; MGC2820; myeloid ecotropic viral integration site-related gene 1; OTTHUMP00000160209; TALE homeobox protein Meis2
Gene Aliases: A430109D20Rik; HsT18361; MEIS2; MRG1; Stra10
UniProt ID: (Human) O14770, (Mouse) P97367
Entrez Gene ID: (Human) 4212, (Mouse) 17536
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcription factor activity, sequence-specific DNA binding
transcription cofactor activity
transcription corepressor activity
protein binding
transcription factor binding
DNA binding
sequence-specific DNA binding
homeodomain transcription factor
negative regulation of transcription from RNA polymerase II promoter
eye development
transcription from RNA polymerase II promoter
visual learning
response to mechanical stimulus
pancreas development
negative regulation of myeloid cell differentiation
positive regulation of transcription from RNA polymerase II promoter
response to growth factor
transcription, DNA-templated
regulation of transcription, DNA-templated
multicellular organism development
regulation of nucleic acid-templated transcription
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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