Proteintech

MEK5 Polyclonal Antibody

Product Image Gallery

MEK5 Antibody in Immunofluorescence (IF) — Immunofluorescent analysis of Hela cells, using MAP2K5 antibody 15758-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IGG (red).

MEK5 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry of paraffin-embedded human testis using 15758-1-AP (MEK5 antibody) at dilution of 1:100 (under 10x lens).

MEK5 Antibody in Western Blot (WB) — HepG2 cells were subjected to SDS PAGE followed by western blot with 15758-1-AP (MEK5 antibody) at dilution of 1:400 incubated at room temperature for 1.5 hours.

Product Details

Tested Applications

Dilution

Immunocytochemistry (ICC)

1:10-1:100

Immunofluorescence (IF)

1:10-1:100

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:200

Western Blot (WB)

1:500-1:2000

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host / Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

MEK5 Fusion Protein Ag8351

Conjugate

Unconjugated

Form

Liquid

Concentration

0.13 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Target Information

MAP2K5 is a dual specificity protein kinase that belongs to the MAP kinase kinase family. It specifically interacts with and activates MAPK7/ERK5. This kinase itself can be phosphorylated and activated by MAP3K3/MEKK3, as well as by atypical protein kinase C isoforms (aPKCs). The signal cascade mediated by MAP2K5 is involved in growth factor stimulated cell proliferation and muscle cell differentiation.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Bioinformatics

Protein Aliases: Dual specificity mitogen-activated protein kinase kinase 5; HsT17454; MAP kinase kinase 5; MAP kinase kinase MEK5b; MAP2K5; MAPK/ERK kinase 5; MAPK/ERK kinese 5; MAPKK 5; MAPKK5; MEK 5; MEK5; mitogen activated protein kinase kinase 5; MKK5; PRKMK5

Gene Aliases: AI324775; AI428457; HsT17454; MAP2K5; MAPKK5; MEK5; MKK5; PRKMK5

UniProt ID: (Human) Q13163, (Mouse) Q9WVS7, (Rat) Q62862

Entrez Gene ID: (Human) 5607, (Mouse) 23938, (Rat) 29568

Function(s)