MERTK is a member of the MER/AXL/TYRO3 receptor kinase family and a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains, and one tyrosine kinase domain. Mutations in MERTK gene have been associated with disruption of the retinal pigment epithelium (RPE) phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa (RP).
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Protein Aliases: c-mer proto-oncogene tyrosine kinase; MER; MER receptor tyrosine kinase; Proto-oncogene c-Mer; Proto-oncogene tyrosine-protein kinase MER; Receptor tyrosine kinase MerTK; STK kinase; Tyrosine-protein kinase Mer
Gene Aliases: c-Eyk; c-mer; MER; MERTK; RP38; Tyro12
UniProt ID: (Human) Q12866
Entrez Gene ID: (Human) 10461