Immunogen sequence: RRCRQRGDAG SPRGCPLCPD DCPAQMQTRT QAEGQGQGRG LGLVSAVRAG ASWGSPPACP GARAAPEPRD PPALFAEAAC PEGQAMEPSP PSPLLPGDVL ALLETWMPLS PLEWLPEEPK; Positive Samples: A-549, HeLa, THP-1, Mouse heart, Rat heart; Cellular Location: Nucleus
Mesp1 (mesoderm posterior 1) is a basic helix-loop-helix-type transcription factor, which along with its related proteins, has an essential role in both segmentation and rostro-caudal patterning of somites in the anterior pre-somitic mesoderm. Mesp1 is expressed in many of the precursors of the cardiovascular system and is known to play a role in the process of cardiac morphogenesis.
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Protein Aliases: bHLHc5; Class C basic helix-loop-helix protein 5; mesoderm posterior 1 homolog; mesoderm posterior basic helix-loop-helix transcription factor 1; Mesoderm posterior protein 1; MGC10676
Gene Aliases: BHLHC5; MESP1