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Abnova
METAP1 Polyclonal Antibody, MaxPab™
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Product Details
H00023173-B01P
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
METAP1 (NP_055958.1, 1 a.a. approximately 272 a.a) full-length human protein.
Conjugate
Form
Liquid
Concentration
0.3 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MSESEQALKG TSQIKLLSSE DIEGMRLVCR LAREVLDVAA GMIKPGVTTE EIDHAVHLAC IARNCYPSPL NYYNFPKSCC TSVNEVICHG IPDRRPLQEG DIVNVDITLY RNGYHGDLNE TFFVGEVDDG ARKLVQTTYE CLMQAIDAVK PGVRYRELGN IIQKHAQANG FSVVRSYCGH GIHKLFHTAP NVPHYAKNKA VGVMKSGHVF TIEPMICEGG WQDETWPDGW TAVTRDGKRS AQFEHTLLVT DTGCEILTRR LDSARPHFMS QF
Target Information
Methionine aminopeptidase 1 (METAP1) is a gene located on chromosome 4q24, encoding an enzyme responsible for the removal of N-terminal methionine residues from newly synthesized proteins. METAP1 is essential for protein maturation and function, as the cleavage of methionine allows subsequent modifications that are crucial for protein stability and activity. This enzyme is ubiquitously expressed in various tissues and plays a significant role in post-translational modification processes, affecting cellular homeostasis and protein regulation. METAP1 is involved in several physiological pathways, including cell cycle progression, signal transduction, and stress response. Dysregulation of METAP1 activity can impact protein function and is associated with diseases like cancer, reflecting its importance in cellular proliferation and growth. Research into METAP1 focuses on its potential as a therapeutic target for modulating protein synthesis and its implications in diseases characterized by uncontrolled cell growth.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: DKFZp781C0419; EC 3.4.11.18; KIAA0094MAP 1; MAP 1; MAP1; metAP 1; Methionine aminopeptidase 1; Peptidase M; Peptidase M 1
Gene Aliases: KIAA0094; MAP1A; METAP1; MetAP1A
UniProt ID: (Human) P53582
Entrez Gene ID: (Human) 23173
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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