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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 172 and 453 of Human METTL3|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 10% glycerol|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:5000-1:20,000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA5-28178 targets METTL3 in WB applications and shows reactivity with Human samples.
The PA5-28178 immunogen is recombinant fragment corresponding to a region within amino acids 172 and 453 of Human METTL3.
This gene encodes the 70 kDa subunit of MT-A which is part of N6-adenosine-methyltransferase. This enzyme is involved in the posttranscriptional methylation of internal adenosine residues in eukaryotic mRNAs, forming N6-methyladenosine.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
adoMet-binding subunit of the human mRNA (N6-adenosine)-methyltransferase; IME4; M6A; methyltransferase-like protein 3; mRNA (2'-O-methyladenosine-N(6)-)-methyltransferase; mRNA m(6)A methyltransferase; Spo8
IME4; M6A; METTL3; MT-A70; MTA70; Spo8