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Invitrogen
MFI2 Polyclonal Antibody
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Product Details
PA5-32921
Product Specifications
Species Reactivity
Bat,
Horse,
Hamster,
Human,
Mouse,
Non-human primate,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic 15 amino acid peptide from N-terminus of human MFI2.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS
Contains
0.1% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Bat, Hamster, Elephant, Panda, Horse (100%); Bovine, Rabbit, Pig (93%); Chicken, Platypus (87%); Dog, Turkey, Medaka, Zebrafish (80%).
For IHC(P), use heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.
Target Information
The protein encoded by this gene is a cell-surface glycoprotein found on melanoma cells. The protein shares sequence similarity and iron-binding properties with members of the transferrin superfamily. The importance of the iron binding function has not yet been identified. This gene resides in the same region of chromosome 3 as members of the transferrin superfamily. Alternative splicing results in two transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5; CD228; Melanoma-associated antigen p97; melanoma-associated antigen p97, isoform 2; Melanotransferrin; membrane-bound transferrin-like protein; Membrane-bound transferrin-like protein p97; MTf
Gene Aliases: CD228; MAP97; MELTF; MFI2; MTf; MTF1
UniProt ID: (Human) P08582, (Mouse) Q9R0R1
Entrez Gene ID: (Horse) 100060123, (Human) 4241, (Mouse) 30060, (Chinese hamster) 100750333, (Rat) 288038
regulation of cell growth
positive regulation of plasminogen activation
regulation of cell proliferation
iron ion homeostasis
positive regulation of extracellular matrix disassembly
iron ion import
negative regulation of substrate adhesion-dependent cell spreading
transport
ion transport
cellular iron ion homeostasis
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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