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There are believed to be over 100 different glycosyltransferases involved in the synthesis of protein-bound and lipid-bound oligosaccharides. UDP-N-acetylglucosamine:alpha-3-D-mannoside beta-1, 2-N-acetylglucosaminyltransferase I is a medial-Golgi enzyme essential for the synthesis of hybrid and complex N-glycans. The protein, encoded by a single exon, shows typical features of a type II transmembrane protein. The protein is believed to be essential for normal embryogenesis. Several variants encoding the same protein have been found for this gene.
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Protein Aliases: Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase; glcNAc-T I; GNT-I; N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase I; OTTHUMP00000161546
Gene Aliases: GGNT1; GLCNAC-TI; GLCT1; GLYT1; GNT-1; GNT-I; GnTI; MGAT; MGAT1
UniProt ID: (Human) P26572
Entrez Gene ID: (Human) 4245
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