Two bands at 130 kDa and 75 kDa could be detected using antibody 66033-1-Ig.
This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This protein forms homo- or hetero-dimers with other Ikaros family members, and is thought to function predominantly in early hematopoietic development. Multiple transcript variants encoding different isoforms have been found for this gene, but the biological validity of some variants has not been determined.
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Protein Aliases: Beta-hexosaminidase; Beta-N-acetylglucosaminidase; Beta-N-acetylhexosaminidase; Bifunctional protein NCOAT; hyaluronidase in meningioma; Meningioma-expressed antigen 5; N-acetyl-beta-D-glucosaminidase; N-acetyl-beta-glucosaminidase; NCOAT; Nuclear cytoplasmic O-GlcNAcase and acetyltransferase; O-GlcNAcase; OGA; Protein O-GlcNAcase
Gene Aliases: 2810009A20Rik; 4833427O07Rik; 5830447M11Rik; AA408215; HEXC; Hy5; KIAA0679; MEA5; MGEA5; mKIAA0679; NCOAT; O-GLCNACASE; OGA