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Proteintech
MGEA5 Polyclonal Antibody
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Product Details
14711-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Fruit fly,
Human,
Mouse,
Pig,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
MGEA5 Fusion Protein Ag6405 (1-350 aa encoded by BC039583)
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Two bands at 130 kDa and 75 kDa could be detected using antibody 66033-1-Ig.
Immunogen sequence: MVQKESQAT LEERESELSS NPAASAGASL EPPAAPAPGE DNPAGAGGAA VAGAAGGARR FLCGVVEGFY GRPWVMEQRK ELFRRLQKWE LNTYLYAPKD DYKHRMFWRE MYSVEEAEQL MTLISAAREY EIEFIYAISP GLDITFSNPK EVSTLKRKLD QVSQFGCRSF ALLFDDIDHN MCAADKEVFS SFAHAQVSIT NEIYQYLGEP ETFLFCPTEY CGTFCYPNVS QSPYLRTVGE KLLPGIEVLW TGPKVVSKEI PVESIEEVSK IIKRAPVIWD NIHANDYDQK RLFLGPYKGR STELIPRLKG VLTNPNCEFE ANYVAIHTLA TWYKSNMNGV RKDVVMSRQV A (1-350 aa encoded by BC039583)
Target Information
This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This protein forms homo- or hetero-dimers with other Ikaros family members, and is thought to function predominantly in early hematopoietic development. Multiple transcript variants encoding different isoforms have been found for this gene, but the biological validity of some variants has not been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Beta-hexosaminidase; Beta-N-acetylglucosaminidase; Beta-N-acetylhexosaminidase; Bifunctional protein NCOAT; hyaluronidase in meningioma; Meningioma-expressed antigen 5; N-acetyl-beta-D-glucosaminidase; N-acetyl-beta-glucosaminidase; NCOAT; Nuclear cytoplasmic O-GlcNAcase and acetyltransferase; O-GlcNAcase; OGA; Protein O-GlcNAcase
Gene Aliases: 2810009A20Rik; 4833427O07Rik; 5830447M11Rik; AA408215; HEXC; Hy5; KIAA0679; MEA5; MGEA5; mKIAA0679; NCOAT; O-GLCNACASE; OGA
UniProt ID: (Human) O60502, (Rat) Q8VIJ5, (Mouse) Q9EQQ9
Entrez Gene ID: (Human) 10724, (Rat) 154968, (Mouse) 76055
N-acetylglucosamine metabolic process
glycoprotein catabolic process
protein deglycosylation
protein targeting to membrane
aging
positive regulation of calcium ion transport into cytosol
negative regulation of cardiac muscle adaptation
histone acetylation
positive regulation of cell killing
positive regulation of insulin secretion
positive regulation of protein complex disassembly
positive regulation of proteolysis
dATP metabolic process
positive regulation of glucose import
response to steroid hormone
positive regulation of DNA metabolic process
positive regulation of mitochondrial depolarization
positive regulation of calcium ion transport
negative regulation of protein glycosylation
positive regulation of growth hormone secretion
necrotic cell death
metabolic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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