This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated. View Details
Immunogen sequence: FYRLTRKVFA NPEDCVAFGK GENAKKYLRT DDR
Highest antigen sequence identity to the following orthologs: Mouse - 73%, Rat - 79%.
The MAPEG (Membrane Associated Proteins in Eicosanoid and Glutathione metabolism) family consists of six human proteins, two of which are involved in the production of leukotrienes and prostaglandin E, important mediators of inflammation. Other family members, demonstrating glutathione S-transferase and peroxidase activities, are involved in cellular defense against toxic, carcinogenic, and pharmacologically active electrophilic compounds. This gene encodes a protein that catalyzes the conjugation of glutathione to electrophiles and the reduction of lipid hydroperoxides. This protein is localized to the endoplasmic reticulum and outer mitochondrial membrane where it is thought to protect these membranes from oxidative stress.
Protein Aliases: glutathione S-transferase 12; MGC14525; Microsomal glutathione S-transferase 1; Microsomal GST-1; Microsomal GST-I
Gene Aliases: GST12; MGST; MGST-I; MGST1
UniProt ID: (Human) P10620
Entrez Gene ID: (Human) 4257