PA5-27343 targets MIF in ELISA, IF, IHC (P), and WB applications and shows reactivity with Human and mouse samples.
The PA5-27343 immunogen is recombinant fragment corresponding to a region within amino acids 1 and 115 of Human MIF.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.
This gene encodes a lymphokine involved in cell-mediated immunity, immunoregulation, and inflammation. It plays a role in the regulation of macrophage function in host defense through the suppression of anti-inflammatory effects of glucocorticoids. This lymphokine and the JAB1 protein form a complex in the cytosol near the peripheral plasma membrane, which may indicate an additional role in integrin signaling pathways.
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Protein Aliases: Delayed early response protein 6; DER6; GIF; GLIF; Glycosylation-inhibiting factor; L-dopachrome isomerase; L-dopachrome tautomerase; Macrophage migration inhibitory factor; MIF; MMIF; Phenylpyruvate tautomerase
Gene Aliases: GIF; GLIF; MIF; MMIF