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This gene encodes a serine/threonine kinase belonging to the germinal center kinase (GCK) family. The protein is structurally similar to the kinases that are related to NIK and may belong to a distinct subfamily of NIK-related kinases within the GCK family. Studies of the mouse homolog indicate an up-regulation of expression in the course of postnatal mouse cerebral development and activation of the cJun N-terminal kinase (JNK) and the p38 pathways.
Protein Aliases: FLJ18426; FLJ38123; FLJ94103; GCK family kinase MINK; hMINK; hMINKbeta; ISK; JLNS; JLNS2; LQT2/5; LQT5; MAPK/ERK kinase kinase kinase 6; MEK kinase kinase 6; MEKKK 6; MGC33114; Mink 1; Mink 2; mink1; Misshapen-like kinase 1; Misshapen/NIK-related kinase; Misshapen/NIKs-related kinase; Mitogen-activated protein kinase kinase kinase kinase 6; Yeast Sps1/Ste20-related kinase 2
Gene Aliases: B55; MAP4K6; MINK; MINK1; YSK2; ZC3
Molecular Function: non-receptor serine/threonine protein kinase