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Product Details
PA5-21725
| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
1:500-1:3,000 | - |
Immunohistochemistry (Paraffin) (IHC (P)) |
1:100-1:1,000 | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Human, Mouse |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
Recombinant fragment corresponding to a region within amino acids 246 and 487 of MIPP (Uniprot ID#Q9UNW1) |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
1 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
PBS, pH 7, with 1% BSA, 20% glycerol |
Contains |
0.01% thimerosal |
Storage conditions |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
RRID |
AB_11152257 |
Product Specific Information
Recommended positive controls: A431, H1299, HeLa, Raji.
Predicted reactivity: Mouse (83%), Rat (85%), Bovine (94%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
MINPP1 encodes multiple inositol polyphosphate phosphatase; an enzyme that removes 3-phosphate from inositol phosphate substrates. It is the only enzyme known to hydrolzye inositol pentakisphosphate and inositol hexakisphosphate. This enzyme also converts 2,3 bisphosphoglycerate (2,3-BPG) to 2-phosphoglycerate; an activity formerly thought to be exclusive to 2,3-BPG synthase/2-phosphatase (BPGM) in the Rapoport-Luebering shunt of the glycolytic pathway.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 2,3-bisphosphoglycerate 3-phosphatase; 2,3-BPG phosphatase; Inositol (1,3,4,5)-tetrakisphosphate 3-phosphatase; Ins(1,3,4,5)P(4) 3-phosphatase; MINP1; multiple inositol polyphosphate histidine phosphatase, 1; Multiple inositol polyphosphate phosphatase 1; multiple inositol polyphosphate phosphatase 2; RP11-57C13.1
Gene Aliases: AA408516; HIPER1; MINPP1; MINPP2; MIPP; MNCb-1572; UNQ900/PRO1917
UniProt ID: (Human) Q9UNW1, (Mouse) Q9Z2L6
Entrez Gene ID: (Human) 9562, (Mouse) 17330
Molecular Function:
phosphatase
acid phosphatase activity
phosphohistidine phosphatase activity
inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase activity
bisphosphoglycerate 3-phosphatase activity
inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity
inositol hexakisphosphate 2-phosphatase activity
inositol-hexakisphosphate phosphatase activity
hydrolase activity
phosphatase activity
inositol-1,4,5,6-tetrakisphosphate 6-phosphatase activity
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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