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Invitrogen
MKKS Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-50453
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Fusion protein corresponding to residues near the C terminal of human McKusick-Kaufman syndrome
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
2.1 mg/mL
Amount
210 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 40% glycerol
Contains
0.05% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
The antibody detects endogenous levels of total MKKS protein.
Target Information
Probable molecular chaperone. Assists the folding of proteins upon ATP hydrolysis. As part of the BBS/CCT complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. May play a role in protein processing in limb, cardiac and reproductive system development. May play a role in cytokinesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: alternative protein MKKS; Bardet-Biedl syndrome 6 protein; McKusick-Kaufman/Bardet-Biedl syndromes putative chaperonin; unnamed protein product
Gene Aliases: BBS6; HMCS; KMS; MKS
UniProt ID: (Human) Q9NPJ1
Entrez Gene ID: (Human) 8195
heart looping
developmental process involved in reproduction
protein folding
spermatid development
determination of left/right symmetry
heart development
sensory perception of smell
gonad development
striatum development
hippocampus development
cerebral cortex development
melanosome transport
developmental process
social behavior
negative regulation of appetite by leptin-mediated signaling pathway
fat cell differentiation
photoreceptor cell maintenance
animal organ development
system development
brain morphogenesis
detection of mechanical stimulus involved in sensory perception of sound
chaperone-mediated protein complex assembly
pigment granule aggregation in cell center
convergent extension involved in gastrulation
cilium morphogenesis
regulation of cilium beat frequency involved in ciliary motility
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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