Immunogen sequence: KSTALKVALF CTTLSGDTSD TGEGTVVVSY GVSLENAVLD QLLNLGRQLI SDHVDLVLCQ KVIHPSLKQF LNMHRIIAID RIGVTLMEPL TK
Highest antigen sequence identity to the following orthologs: Mouse - 72%, Rat - 80%.
Probable molecular chaperone. Assists the folding of proteins upon ATP hydrolysis. As part of the BBS/CCT complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. May play a role in protein processing in limb, cardiac and reproductive system development. May play a role in cytokinesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Bardet-Biedl syndrome 6 protein; McKusick-Kaufman/Bardet-Biedl syndromes putative chaperonin
Gene Aliases: BBS6; HMCS; KMS; MKKS; MKS
UniProt ID: (Human) Q9NPJ1
Entrez Gene ID: (Human) 8195
Molecular Function: chaperone