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Proteintech
MKS1 Polyclonal Antibody
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Product Details
16206-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
MKS1 Fusion Protein Ag9177 (1-321 aa encoded by BC010061)
Conjugate
Form
Liquid
Concentration
0.24 mg/mL
Amount
36 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MTTAASEVP SFLVERMANV RRRRQDRRGM EGGILKSRIV TWEPSEEFVR NNHVINTPLQ TMHIMADLGP YKKLGYKKYE HVLCTLKVDS NGVITVKPDF TGLKGPYRIE TEGEKQELWK YTIDNVSPHA QPEEEERERR VFKDLYGRHK EYLSSLVGTD FEMTVPGALR LFVNGEVVSA QGYEYDNLYV HFFVELPTAH WSSPAFQQLS GVTQTCTTKS LAMDKVAHFS YPFTFEAFFL HEDESSDALP EWPVLYCEVL SLDFWQRYRV EGYGAVVLPA TPGSHTLTVS TWRPVELGTV AELRRFFIGG SLELEDLSYV RI (1-321 aa encoded by BC010061)
Target Information
The protein encoded by this gene localizes to the basal body and is required for formation of the primary cilium in ciliated epithelial cells. Mutations in this gene result in Meckel syndrome type 1 and in Bardet-Biedl syndrome type 13. Multiple transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: FLJ20345; Meckel syndrome type 1 protein; Meckel syndrome type 1 protein homolog; POC12 centriolar protein homolog; Tectonic-like complex member MKS1; unnamed protein product
Gene Aliases: AK190930; B8d3; BBS13; JBTS28; MES; MKS; MKS1; POC12
UniProt ID: (Human) Q9NXB0, (Mouse) Q5SW45, (Rat) Q499Q5
Entrez Gene ID: (Human) 54903, (Mouse) 380718, (Rat) 287612
neural tube closure
smoothened signaling pathway involved in regulation of secondary heart field cardioblast proliferation
determination of left/right symmetry
regulation of smoothened signaling pathway
epithelial structure maintenance
cell projection organization
embryonic digit morphogenesis
motile cilium assembly
embryonic skeletal system development
branching morphogenesis of an epithelial tube
inner ear receptor stereocilium organization
cilium morphogenesis
head development
cardiac septum morphogenesis
regulation of canonical Wnt signaling pathway
common bile duct development
non-motile cilium assembly
embryonic brain development
regulation of Wnt signaling pathway, planar cell polarity pathway
nonmotile primary cilium assembly
cilium assembly
regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
motile primary cilium assembly
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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