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| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
0.04-0.4 µg/mL | - |
Immunohistochemistry (IHC) |
1:50-1:200 | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Human, Rat |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
Recombinant protein corresponding to Human MKS1 |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
0.2 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
PBS, pH 7.2, with 40% glycerol |
Contains |
0.02% sodium azide |
Storage conditions |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
RRID |
AB_2643995 |
Immunogen sequence: EVPSFLVERM ANVRRRRQDR RGMEGGILKS RIVTWEPSEE FVRNNHVINT PLQTMHIMAD LGPYKKLGYK KYEHVLCTLK VDSNGVITVK PDFTGLKGPY RI
Highest antigen sequence identity to the following orthologs: Mouse - 86%, Rat - 85%.
The protein encoded by this gene localizes to the basal body and is required for formation of the primary cilium in ciliated epithelial cells. Mutations in this gene result in Meckel syndrome type 1 and in Bardet-Biedl syndrome type 13. Multiple transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Meckel syndrome type 1 protein; Meckel syndrome type 1 protein homolog; POC12 centriolar protein homolog
Gene Aliases: BBS13; MES; MKS; MKS1; POC12
UniProt ID: (Human) Q9NXB0, (Rat) Q499Q5
Entrez Gene ID: (Human) 54903, (Rat) 287612
Molecular Function:
structural protein
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