Product References
Proteomic signature for detection of high-grade ovarian cancer in germline BRCA mutation carriers.
International journal of cancer
Bahar-Shany K,Barnabas GD,Deutsch L,Deutsch N,Glick-Saar E,Dominissini D,Sapoznik S,Helpman L,Perri T,Blecher A,Katz G,Yagel I,Rosenblatt O,Shai D,Brandt B,Meyer R,Mohr-Sasson A,Volodarsky-Perel A,Zilberman I,Armon S,Jakobson-Setton A,Eitan R,Kadan Y,Beiner M,Josephy D,Brodsky M,Friedman E,Anafi L,Molchanov Y,Korach J,Geiger T,Levanon K
Wed Feb 15 00:00:00 UTC 2023
Interpreting ciliopathy-associated missense variants of uncertain significance (VUS) in Caenorhabditis elegans.
Human molecular genetics
Lange KI,Best S,Tsiropoulou S,Berry I,Johnson CA,Blacque OE
Thu May 19 00:00:00 UTC 2022
Variable phenotypes and penetrance between and within different zebrafish ciliary transition zone mutants.
Disease models & mechanisms
Wang J,Thomas HR,Thompson RG,Waldrep SC,Fogerty J,Song P,Li Z,Ma Y,Santra P,Hoover JD,Yeo NC,Drummond IA,Yoder BK,Amack JD,Perkins B,Parant JM
Thu Dec 01 00:00:00 UTC 2022
The ciliary gene INPP5E confers dorsal telencephalic identity to human cortical organoids by negatively regulating Sonic hedgehog signaling.
Cell reports
Schembs L,Willems A,Hasenpusch-Theil K,Cooper JD,Whiting K,Burr K,Bøstrand SMK,Selvaraj BT,Chandran S,Theil T
Tue May 17 00:00:00 UTC 2022
LUBAC regulates ciliogenesis by promoting CP110 removal from the mother centriole.
The Journal of cell biology
Shen XL,Yuan JF,Qin XH,Song GP,Hu HB,Tu HQ,Song ZQ,Li PY,Xu YL,Li S,Jian XX,Li JN,He CY,Yu XP,Liang LY,Wu M,Han QY,Wang K,Li AL,Zhou T,Zhang YC,Wang N,Li HY
Mon Jan 03 00:00:00 UTC 2022
Superresolution Microscopy Reveals Distinct Phosphoinositide Subdomains Within the Cilia Transition Zone.
Frontiers in cell and developmental biology
Conduit SE,Davies EM,Fulcher AJ,Oorschot V,Mitchell CA
Tue May 18 00:00:00 UTC 2021
Disrupted intraflagellar transport due to IFT74 variants causes Joubert syndrome.
Genetics in medicine : official journal of the American College of Medical Genetics
Luo M,Lin Z,Zhu T,Jin M,Meng D,He R,Cao Z,Shen Y,Lu C,Cai R,Zhao Y,Wang X,Li H,Wu S,Zou X,Luo G,Cao L,Huang M,Jiao H,Gao H,Sui R,Zhao C,Ma X,Cao M
Tue Jun 01 00:00:00 UTC 2021
ASK1-Mediated Phosphorylation Blocks HDAC6 Ubiquitination and Degradation to Drive the Disassembly of Photoreceptor Connecting Cilia.
Developmental cell
Ran J,Liu M,Feng J,Li H,Ma H,Song T,Cao Y,Zhou P,Wu Y,Yang Y,Yang Y,Yu F,Guo H,Zhang L,Xie S,Li D,Gao J,Zhang X,Zhu X,Zhou J
Mon May 04 00:00:00 UTC 2020
Investigation of F-BAR domain PACSIN proteins uncovers membrane tubulation function in cilia assembly and transport.
Nature communications
Insinna C,Lu Q,Teixeira I,Harned A,Semler EM,Stauffer J,Magidson V,Tiwari A,Kenworthy AK,Narayan K,Westlake CJ
Fri Jan 25 00:00:00 UTC 2019
Targeted exon skipping rescues ciliary protein composition defects in Joubert syndrome patient fibroblasts.
Scientific reports
Molinari E,Ramsbottom SA,Srivastava S,Booth P,Alkanderi S,McLafferty SM,Devlin LA,White K,Gunay-Aygun M,Miles CG,Sayer JA
Thu Jul 25 00:00:00 UTC 2019
Cell type-specific regulation of ciliary transition zone assembly in vertebrates.
The EMBO journal
Wiegering A,Dildrop R,Kalfhues L,Spychala A,Kuschel S,Lier JM,Zobel T,Dahmen S,Leu T,Struchtrup A,Legendre F,Vesque C,Schneider-Maunoury S,Saunier S,Rüther U,Gerhardt C
Tue May 15 00:00:00 UTC 2018
Cell type-specific regulation of ciliary transition zone assembly in vertebrates.
The EMBO journal
Wiegering A,Dildrop R,Kalfhues L,Spychala A,Kuschel S,Lier JM,Zobel T,Dahmen S,Leu T,Struchtrup A,Legendre F,Vesque C,Schneider-Maunoury S,Saunier S,Rüther U,Gerhardt C
Tue May 15 00:00:00 UTC 2018
Oncoprotein CIP2A promotes the disassembly of primary cilia and inhibits glycolytic metabolism.
EMBO reports
Jeong AL,Ka HI,Han S,Lee S,Lee EW,Soh SJ,Joo HJ,Sumiyasuren B,Park JY,Lim JS,Park JH,Lee MS,Yang Y
Tue May 01 00:00:00 UTC 2018
Oncoprotein CIP2A promotes the disassembly of primary cilia and inhibits glycolytic metabolism.
EMBO reports
Jeong AL,Ka HI,Han S,Lee S,Lee EW,Soh SJ,Joo HJ,Sumiyasuren B,Park JY,Lim JS,Park JH,Lee MS,Yang Y
Tue May 01 00:00:00 UTC 2018
Super-Resolution Imaging Reveals TCTN2 Depletion-Induced IFT88 Lumen Leakage and Ciliary Weakening.
Biophysical journal
Weng RR,Yang TT,Huang CE,Chang CW,Wang WJ,Liao JC
Tue Jul 17 00:00:00 UTC 2018
Super-Resolution Imaging Reveals TCTN2 Depletion-Induced IFT88 Lumen Leakage and Ciliary Weakening.
Biophysical journal
Weng RR,Yang TT,Huang CE,Chang CW,Wang WJ,Liao JC
Tue Jul 17 00:00:00 UTC 2018
Microtubule asters anchored by FSD1 control axoneme assembly and ciliogenesis.
Nature communications
Tu HQ,Qin XH,Liu ZB,Song ZQ,Hu HB,Zhang YC,Chang Y,Wu M,Huang Y,Bai YF,Wang G,Han QY,Li AL,Zhou T,Liu F,Zhang XM,Li HY
Tue Dec 11 00:00:00 UTC 2018
Microtubule asters anchored by FSD1 control axoneme assembly and ciliogenesis.
Nature communications
Tu HQ,Qin XH,Liu ZB,Song ZQ,Hu HB,Zhang YC,Chang Y,Wu M,Huang Y,Bai YF,Wang G,Han QY,Li AL,Zhou T,Liu F,Zhang XM,Li HY
Tue Dec 11 00:00:00 UTC 2018
Dynein-2 intermediate chains play crucial but distinct roles in primary cilia formation and function.
eLife
Vuolo L,Stevenson NL,Heesom KJ,Stephens DJ
Tue Oct 16 00:00:00 UTC 2018
Dynein-2 intermediate chains play crucial but distinct roles in primary cilia formation and function.
eLife
Vuolo L,Stevenson NL,Heesom KJ,Stephens DJ
Tue Oct 16 00:00:00 UTC 2018
The daughter centriole controls ciliogenesis by regulating Neurl-4 localization at the centrosome.
The Journal of cell biology
Loukil A,Tormanen K,Sütterlin C
Mon May 01 00:00:00 UTC 2017
The daughter centriole controls ciliogenesis by regulating Neurl-4 localization at the centrosome.
The Journal of cell biology
Loukil A,Tormanen K,Sütterlin C
Mon May 01 00:00:00 UTC 2017
In Vitro Modeling Using Ciliopathy-Patient-Derived Cells Reveals Distinct Cilia Dysfunctions Caused by CEP290 Mutations.
Cell reports
Shimada H,Lu Q,Insinna-Kettenhofen C,Nagashima K,English MA,Semler EM,Mahgerefteh J,Cideciyan AV,Li T,Brooks BP,Gunay-Aygun M,Jacobson SG,Cogliati T,Westlake CJ,Swaroop A
Tue Jul 11 00:00:00 UTC 2017
In Vitro Modeling Using Ciliopathy-Patient-Derived Cells Reveals Distinct Cilia Dysfunctions Caused by CEP290 Mutations.
Cell reports
Shimada H,Lu Q,Insinna-Kettenhofen C,Nagashima K,English MA,Semler EM,Mahgerefteh J,Cideciyan AV,Li T,Brooks BP,Gunay-Aygun M,Jacobson SG,Cogliati T,Westlake CJ,Swaroop A
Tue Jul 11 00:00:00 UTC 2017
Early steps in primary cilium assembly require EHD1/EHD3-dependent ciliary vesicle formation.
Nature cell biology
Lu Q,Insinna C,Ott C,Stauffer J,Pintado PA,Rahajeng J,Baxa U,Walia V,Cuenca A,Hwang YS,Daar IO,Lopes S,Lippincott-Schwartz J,Jackson PK,Caplan S,Westlake CJ
Wed Apr 01 00:00:00 UTC 2015
Early steps in primary cilium assembly require EHD1/EHD3-dependent ciliary vesicle formation.
Nature cell biology
Lu Q,Insinna C,Ott C,Stauffer J,Pintado PA,Rahajeng J,Baxa U,Walia V,Cuenca A,Hwang YS,Daar IO,Lopes S,Lippincott-Schwartz J,Jackson PK,Caplan S,Westlake CJ
Wed Apr 01 00:00:00 UTC 2015
Early steps in primary cilium assembly require EHD1/EHD3-dependent ciliary vesicle formation.
Nature cell biology
Lu Q,Insinna C,Ott C,Stauffer J,Pintado PA,Rahajeng J,Baxa U,Walia V,Cuenca A,Hwang YS,Daar IO,Lopes S,Lippincott-Schwartz J,Jackson PK,Caplan S,Westlake CJ
Sun Mar 01 00:00:00 UTC 2015
Early steps in primary cilium assembly require EHD1/EHD3-dependent ciliary vesicle formation.
Nature cell biology
Lu Q,Insinna C,Ott C,Stauffer J,Pintado PA,Rahajeng J,Baxa U,Walia V,Cuenca A,Hwang YS,Daar IO,Lopes S,Lippincott-Schwartz J,Jackson PK,Caplan S,Westlake CJ
Sun Mar 01 00:00:00 UTC 2015
TMEM231, mutated in orofaciodigital and Meckel syndromes, organizes the ciliary transition zone.
The Journal of cell biology
Roberson EC,Dowdle WE,Ozanturk A,Garcia-Gonzalo FR,Li C,Halbritter J,Elkhartoufi N,Porath JD,Cope H,Ashley-Koch A,Gregory S,Thomas S,Sayer JA,Saunier S,Otto EA,Katsanis N,Davis EE,Attié-Bitach T,Hildebrandt F,Leroux MR,Reiter JF
Mon Apr 13 00:00:00 UTC 2015
TMEM231, mutated in orofaciodigital and Meckel syndromes, organizes the ciliary transition zone.
The Journal of cell biology
Roberson EC,Dowdle WE,Ozanturk A,Garcia-Gonzalo FR,Li C,Halbritter J,Elkhartoufi N,Porath JD,Cope H,Ashley-Koch A,Gregory S,Thomas S,Sayer JA,Saunier S,Otto EA,Katsanis N,Davis EE,Attié-Bitach T,Hildebrandt F,Leroux MR,Reiter JF
Mon Apr 13 00:00:00 UTC 2015
Nephrocystin proteins NPHP5 and Cep290 regulate BBSome integrity, ciliary trafficking and cargo delivery.
Human molecular genetics
Barbelanne M,Hossain D,Chan DP,Peränen J,Tsang WY
Wed Apr 15 00:00:00 UTC 2015
Nephrocystin proteins NPHP5 and Cep290 regulate BBSome integrity, ciliary trafficking and cargo delivery.
Human molecular genetics
Barbelanne M,Hossain D,Chan DP,Peränen J,Tsang WY
Wed Apr 15 00:00:00 UTC 2015
Superresolution Pattern Recognition Reveals the Architectural Map of the Ciliary Transition Zone.
Scientific reports
Yang TT,Su J,Wang WJ,Craige B,Witman GB,Tsou MF,Liao JC
Mon Sep 14 00:00:00 UTC 2015
Superresolution Pattern Recognition Reveals the Architectural Map of the Ciliary Transition Zone.
Scientific reports
Yang TT,Su J,Wang WJ,Craige B,Witman GB,Tsou MF,Liao JC
Mon Sep 14 00:00:00 UTC 2015
Deacetylation of α-tubulin and cortactin is required for HDAC6 to trigger ciliary disassembly.
Scientific reports
Ran J,Yang Y,Li D,Liu M,Zhou J
Thu Aug 06 00:00:00 UTC 2015
Deacetylation of α-tubulin and cortactin is required for HDAC6 to trigger ciliary disassembly.
Scientific reports
Ran J,Yang Y,Li D,Liu M,Zhou J
Thu Aug 06 00:00:00 UTC 2015
CYLD mediates ciliogenesis in multiple organs by deubiquitinating Cep70 and inactivating HDAC6.
Cell research
Yang Y,Ran J,Liu M,Li D,Li Y,Shi X,Meng D,Pan J,Ou G,Aneja R,Sun SC,Zhou J
Sat Nov 01 00:00:00 UTC 2014
CYLD mediates ciliogenesis in multiple organs by deubiquitinating Cep70 and inactivating HDAC6.
Cell research
Yang Y,Ran J,Liu M,Li D,Li Y,Shi X,Meng D,Pan J,Ou G,Aneja R,Sun SC,Zhou J
Sat Nov 01 00:00:00 UTC 2014
CEP162 is an axoneme-recognition protein promoting ciliary transition zone assembly at the cilia base.
Nature cell biology
Wang WJ,Tay HG,Soni R,Perumal GS,Goll MG,Macaluso FP,Asara JM,Amack JD,Tsou MF
Sat Jun 01 00:00:00 UTC 2013
CEP162 is an axoneme-recognition protein promoting ciliary transition zone assembly at the cilia base.
Nature cell biology
Wang WJ,Tay HG,Soni R,Perumal GS,Goll MG,Macaluso FP,Asara JM,Amack JD,Tsou MF
Sat Jun 01 00:00:00 UTC 2013
CEP162 is an axoneme-recognition protein promoting ciliary transition zone assembly at the cilia base.
Nature cell biology
Wang WJ,Tay HG,Soni R,Perumal GS,Goll MG,Macaluso FP,Asara JM,Amack JD,Tsou MF
Sat Jun 01 00:00:00 UTC 2013
CEP162 is an axoneme-recognition protein promoting ciliary transition zone assembly at the cilia base.
Nature cell biology
Wang WJ,Tay HG,Soni R,Perumal GS,Goll MG,Macaluso FP,Asara JM,Amack JD,Tsou MF
Sat Jun 01 00:00:00 UTC 2013
The spinocerebellar ataxia-associated gene Tau tubulin kinase 2 controls the initiation of ciliogenesis.
Cell
Goetz SC,Liem KF,Anderson KV
Fri Nov 09 00:00:00 UTC 2012
The spinocerebellar ataxia-associated gene Tau tubulin kinase 2 controls the initiation of ciliogenesis.
Cell
Goetz SC,Liem KF,Anderson KV
Fri Nov 09 00:00:00 UTC 2012
A transition zone complex regulates mammalian ciliogenesis and ciliary membrane composition.
Nature genetics
Garcia-Gonzalo FR,Corbit KC,Sirerol-Piquer MS,Ramaswami G,Otto EA,Noriega TR,Seol AD,Robinson JF,Bennett CL,Josifova DJ,García-Verdugo JM,Katsanis N,Hildebrandt F,Reiter JF
Sun Jul 03 00:00:00 UTC 2011
A transition zone complex regulates mammalian ciliogenesis and ciliary membrane composition.
Nature genetics
Garcia-Gonzalo FR,Corbit KC,Sirerol-Piquer MS,Ramaswami G,Otto EA,Noriega TR,Seol AD,Robinson JF,Bennett CL,Josifova DJ,García-Verdugo JM,Katsanis N,Hildebrandt F,Reiter JF
Sun Jul 03 00:00:00 UTC 2011
A transition zone complex regulates mammalian ciliogenesis and ciliary membrane composition.
Nature genetics
Garcia-Gonzalo FR,Corbit KC,Sirerol-Piquer MS,Ramaswami G,Otto EA,Noriega TR,Seol AD,Robinson JF,Bennett CL,Josifova DJ,García-Verdugo JM,Katsanis N,Hildebrandt F,Reiter JF
Sun Jul 03 00:00:00 UTC 2011
