|Tested Species reactivity||Human|
|Host / Isotype||Goat / IgG|
|Immunogen||Synthetic peptide sequence (CNCGAKRCRRFLN) corresponding to the C-terminus amino acids of MLL4|
|Purification||Antigen affinity chromatography|
|Storage buffer||TBS, pH 7.3, with 0.5% BSA|
|Contains||0.02% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
This antibody is predicted to react with canine, mouse, porcine and rat based on sequence homology.
This gene encodes a protein which contains multiple domains including a CXXC zinc finger, three PHD zinc fingers, two FY-rich domains, and a SET domain. The SET domain is a conserved C-terminal domain that characterizes proteins of the MLL family. This gene is ubiquitously expressed in adult tissues. It is also amplified in solid tumor cell lines, and may be involved in human cancer. Two alternatively spliced transcript variants encoding distinct isoforms have been reported for this gene, however, the full length nature of the shorter transcript is not known.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Histone-lysine N-methyltransferase 2B; histone-lysine N-methyltransferase MLL4; HRX2; KIAA0304; KIAA0304 gene product; lysine (K)-specific methyltransferase 2B; Lysine N-methyltransferase 2B; mixed lineage leukemia gene homolog 2; MLL2; MLL4; myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila) 4; myeloid/lymphoid or mixed-lineage leukemia 4; Myeloid/lymphoid or mixed-lineage leukemia protein 4; Trithorax homolog 2; trithorax homologue 2; WBP-7; WW domain binding protein 7; WW domain-binding protein 7
Gene Aliases: CXXC10; HRX2; KIAA0304; KMT2B; MLL1B; MLL2; MLL4; TRX2; WBP-7; WBP7
UniProt ID: (Human) Q9UMN6
Entrez Gene ID: (Human) 9757
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