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Product Details
13256-1-AP
| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
1:500-1:2,000 | View 1 publication 1 publication |
Immunoprecipitation (IP) |
0.5-4.0 µg | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Human |
Published species |
Not Applicable |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
MLXIPL Fusion Protein Ag3481 (1-350 aa encoded by BC012925) |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
0.28 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
PBS, pH 7.3, with 50% glycerol |
Contains |
0.02% sodium azide |
Storage conditions |
-20°C |
Product Specific Information
Immunogen sequence: MAGALAGLA AGLQVPRVAP SPDSDSDTDS EDPSLRRSAG GLLRSQVIHS GHFMVSSPHS DSLPRRRDQE GSVGPSDFGP RSIDPTLTRL FECLSLAYSG KLVSPKWKNF KGLKLLCRDK IRLNNAIWRA WYIQYVKRRK SPVCGFVTPL QGPEADAHRK PEAVVLEGNY WKRRIELPPE DAYVGNADMI QPDLTPLQPS LDDFMDISDF FTNSRLPQPP MPSNFPEPPS FSPVVDSLFS SGTLGPEVPP ASSAMTHLSG HSRLQARNSC PGPLDSSAFL SSDFLLPEDP KPRLPPPPVP PPLLHYPPPA KVPGLEPCPP PPFPPMAPPT ALLQEEPLFS PRFPFPTVPP A (1-350 aa encoded by BC012925)
Target Information
ChREBP is a transcription factor involved in activating genes that encode enzymes of fatty acid biosynthesis in liver and adipose. This protein may have relevance to lipid metabolism, obesity, and type II diabetes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: bHLHd14; carbohydrate response element binding protein; Carbohydrate-responsive element-binding protein; ChREBP; Class D basic helix-loop-helix protein 14; MLX interacting protein-like; MLX interactor; MLX-interacting protein-like; Williams Beuren syndrome chromosome region 14; Williams-Beuren syndrome chromosomal region 14 protein; Williams-Beuren syndrome chromosome region 14 protein 1; Williams-Beuren syndrome chromosome region 14 protein 2; Williams-Beuren syndrome chromosome region 14 protein 3; WS basic-helix-loop-helix leucine zipper protein; WS-bHLH
Gene Aliases: BHLHD14; CHREBP; MIO; MLXIPL; MONDOB; WBSCR14; WS-bHLH
UniProt ID: (Human) Q9NP71
Entrez Gene ID: (Human) 51085
Molecular Function:
DNA-binding transcription factor
negative regulation of transcription from RNA polymerase II promoter
transcription, DNA-templated
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
positive regulation of cell proliferation
anatomical structure morphogenesis
glucose mediated signaling pathway
negative regulation of peptidyl-serine phosphorylation
intracellular signal transduction
glucose homeostasis
positive regulation of fatty acid biosynthetic process
positive regulation of glycolytic process
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
positive regulation of lipid biosynthetic process
fatty acid homeostasis
triglyceride homeostasis
negative regulation of cell cycle arrest
cellular response to carbohydrate stimulus
negative regulation of oxidative phosphorylation
regulation of energy homeostasis
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
DNA binding
transcription factor activity, sequence-specific DNA binding
transcription factor binding
carbohydrate response element binding
protein homodimerization activity
protein heterodimerization activity
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