Peptide sequence: APRLLDFQKT KYARFMNHRV PAHKRYQPTE YEHAANCATH AFWIIPSILG
Sequence homology: Cow: 100%; Dog: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%
This gene encodes a member of the PAQR (progestin and adipoQ receptor) family. Members of this family are evolutionarily conserved with significant sequence identity to bacterial hemolysin-like proteins and are defined by a set of seven transmembrane domains. The protein encoded by this gene localizes to the Golgi apparatus to modulate Ras signaling. Alternative splicing results in multiple transcript variants and protein isoforms.
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Protein Aliases: Monocyte to macrophage differentiation factor 2; monocyte to macrophage differentiation-associated 2; monocyte-to-macrophage differentiation factor 2; monocyte-to-macrophage differentiation-associated protein 2; Progestin and adipoQ receptor family member 10; Progestin and adipoQ receptor family member X
Gene Aliases: MMD2; PAQR10
UniProt ID: (Human) Q8IY49
Entrez Gene ID: (Human) 221938
Molecular Function: G-protein coupled receptor