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MMP-7 Polyclonal Antibody
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Product Details
BS-0423R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from mouse MMP7, amino acids 151-250.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades proteoglycans, fibronectin, elastin and casein and differs from most MMP family members in that it lacks a conserved C-terminal protein domain. The enzyme is involved in wound healing, and studies in mice suggest that it regulates the activity of defensins in intestinal mucosa. The gene is part of a cluster of MMP genes which localize to chromosome 11q22. 3.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: HGNC:7174; Matrilysin; matrilysin, uterine; Matrin; matrix metallo protease; matrix metallopeptidase 7 (matrilysin, uterine); matrix metalloproteinase 7; Matrix metalloproteinase 7 (matrilysin); matrix metalloproteinase 7 (matrilysin, uterine); Matrix metalloproteinase-7; MMP; MMP 7; MMP-7; MMPs; PUMP 1; Pump 1 protease; Pump-1 protease; unnamed protein product; uterine matrilysin; Uterine metalloproteinase
Gene Aliases: MAT; MMP-7; MMP7; MPMM; MPSL1; PUMP-1; PUMP1
UniProt ID: (Human) P09237, (Rat) P50280, (Mouse) Q10738
Entrez Gene ID: (Human) 4316, (Rat) 25335, (Mouse) 17393
antibacterial peptide secretion
antibacterial peptide biosynthetic process
proteolysis
membrane protein ectodomain proteolysis
response to xenobiotic stimulus
extracellular matrix disassembly
extracellular matrix organization
positive regulation of cell migration
collagen catabolic process
membrane protein intracellular domain proteolysis
regulation of cell proliferation
defense response to bacterium
defense response to Gram-negative bacterium
defense response to Gram-positive bacterium
aging
response to nutrient levels
response to drug
estrous cycle
maternal process involved in female pregnancy
cellular response to mechanical stimulus
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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