Product References
Tumor-derived exosomes educate dendritic cells to promote tumor metastasis via HSP72/HSP105-TLR2/TLR4 pathway.
Oncoimmunology
Shen Y,Guo D,Weng L,Wang S,Ma Z,Yang Y,Wang P,Wang J,Cai Z
Tue Jan 12 00:00:00 EST 2021
Chondroprotective Effects and Multitarget Mechanisms of Fu Yuan Capsule in a Rat Osteoarthritis Model.
Evidence-based complementary and alternative medicine : eCAM
Zeng L,Xiao CZ,Deng ZT,Li RH
Thu Oct 01 00:00:00 EDT 2020
SIRT3 Activation by Dihydromyricetin Suppresses Chondrocytes Degeneration via Maintaining Mitochondrial Homeostasis.
International journal of biological sciences
Wang J,Wang K,Huang C,Lin D,Zhou Y,Wu Y,Tian N,Fan P,Pan X,Xu D,Hu J,Zhou Y,Wang X,Zhang X
Mon Sep 09 00:00:00 EDT 2019
Effects of IL-1β on MMP-9 Expression in Cementoblast-Derived Cell Line and MMP-Mediated Degradation of Type I Collagen.
Inflammation
Du M,Wang Y,Liu Z,Wang L,Cao Z,Zhang C,Hao Y,He H
Mon Apr 01 00:00:00 EDT 2019
mTOR-mediated inactivation of 4E-BP1, an inhibitor of translation, precedes cartilage degeneration in rat osteoarthritic knees.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society
Katsara O,Kolupaeva V
Mon Oct 01 00:00:00 EDT 2018
Emodin ameliorates cartilage degradation in osteoarthritis by inhibiting NF-κB and Wnt/β-catenin signaling in-vitro and in-vivo.
International immunopharmacology
Ding QH,Ye CY,Chen EM,Zhang W,Wang XH
Wed Aug 01 00:00:00 EDT 2018
ETV4 transcription factor and MMP13 metalloprotease are interplaying actors of breast tumorigenesis.
Breast cancer research : BCR
Dumortier M,Ladam F,Damour I,Vacher S,Bièche I,Marchand N,de Launoit Y,Tulasne D,Chotteau-Lelièvre A
Wed Jul 11 00:00:00 EDT 2018
ETV4 transcription factor and MMP13 metalloprotease are interplaying actors of breast tumorigenesis.
Breast cancer research : BCR
Dumortier M,Ladam F,Damour I,Vacher S,Bièche I,Marchand N,de Launoit Y,Tulasne D,Chotteau-Lelièvre A
Wed Jul 11 00:00:00 EDT 2018
Upregulation of FBXW7 Suppresses Renal Cancer Metastasis and Epithelial Mesenchymal Transition.
Disease markers
Cai Y,Zhang M,Qiu X,Wang B,Fu Y,Zeng J,Bai J,Yang G
Fri Jun 22 00:00:00 EDT 2018
Differential effects of high-physiological oestrogen on the degeneration of mandibular condylar cartilage and subchondral bone.
Bone
Ye T,Sun D,Mu T,Chu Y,Miao H,Zhang M,Yang H,Liu Q,Lu L,Xing X,Yu S
Fri Jun 01 00:00:00 EDT 2018
Toxoplasma gondii GRA15II effector-induced M1 cells ameliorate liver fibrosis in mice infected with Schistosomiasis japonica.
Cellular & molecular immunology
Xie Y,Wen H,Yan K,Wang S,Wang X,Chen J,Li Y,Xu Y,Zhong Z,Shen J,Chu D
Thu Feb 01 00:00:00 EST 2018
Postnatal deletion of Alk5 gene in meniscal cartilage accelerates age-dependent meniscal degeneration in mice.
Journal of cellular physiology
Wang Q,Tan Q,Xu W,Kuang L,Zhang B,Wang Z,Ni Z,Su N,Jin M,Li C,Jiang W,Huang J,Li F,Zhu Y,Chen H,Du X,Chen D,Deng C,Qi H,Xie Y,Chen L
Mon Jan 01 00:00:00 EST 2018
Cartilage-specific deletion of Alk5 gene results in a progressive osteoarthritis-like phenotype in mice.
Osteoarthritis and cartilage
Wang Q,Tan QY,Xu W,Qi HB,Chen D,Zhou S,Ni ZH,Kuang L,Guo JY,Huang JL,Wang XX,Wang ZQ,Su N,Chen L,Chen B,Jiang WL,Gao Y,Chen HG,Du XL,Xie YL,Chen L
Wed Nov 01 00:00:00 EDT 2017
Cartilage-specific deletion of Alk5 gene results in a progressive osteoarthritis-like phenotype in mice.
Osteoarthritis and cartilage
Wang Q,Tan QY,Xu W,Qi HB,Chen D,Zhou S,Ni ZH,Kuang L,Guo JY,Huang JL,Wang XX,Wang ZQ,Su N,Chen L,Chen B,Jiang WL,Gao Y,Chen HG,Du XL,Xie YL,Chen L
Wed Nov 01 00:00:00 EDT 2017
Chlorogenic acid prevents inflammatory responses in IL‑1β‑stimulated human SW‑1353 chondrocytes, a model for osteoarthritis.
Molecular medicine reports
Liu CC,Zhang Y,Dai BL,Ma YJ,Zhang Q,Wang Y,Yang H
Tue Aug 01 00:00:00 EDT 2017
Conditional knockdown of hyaluronidase 2 in articular cartilage stimulates osteoarthritic progression in a mice model.
Scientific reports
Higuchi Y,Nishida Y,Kozawa E,Zhuo L,Arai E,Hamada S,Morita D,Ikuta K,Kimata K,Ushida T,Ishiguro N
Tue Aug 01 00:00:00 EDT 2017
Potential Involvement of the IL-6/JAK/STAT3 Pathway in the Pathogenesis of Intervertebral Disc Degeneration.
Spine
Suzuki S,Fujita N,Fujii T,Watanabe K,Yagi M,Tsuji T,Ishii K,Miyamoto T,Horiuchi K,Nakamura M,Matsumoto M
Sat Jul 15 00:00:00 EDT 2017
Icariin inhibits MMP‑1, MMP‑3 and MMP‑13 expression through MAPK pathways in IL‑1β‑stimulated SW1353 chondrosarcoma cells.
Molecular medicine reports
Zeng L,Rong XF,Li RH,Wu XY
Mon May 01 00:00:00 EDT 2017
AMPK deficiency in chondrocytes accelerated the progression of instability-induced and ageing-associated osteoarthritis in adult mice.
Scientific reports
Zhou S,Lu W,Chen L,Ge Q,Chen D,Xu Z,Shi D,Dai J,Li J,Ju H,Cao Y,Qin J,Chen S,Teng H,Jiang Q
Wed Feb 22 00:00:00 EST 2017
Exogenous fibroblast growth factor 9 attenuates cartilage degradation and aggravates osteophyte formation in post-traumatic osteoarthritis.
Osteoarthritis and cartilage
Zhou S,Wang Z,Tang J,Li W,Huang J,Xu W,Luo F,Xu M,Wang J,Wen X,Chen L,Chen H,Su N,Shen Y,Du X,Xie Y,Chen L
Thu Dec 01 00:00:00 EST 2016
Deletion of Dual Specificity Phosphatase 1 Does Not Predispose Mice to Increased Spontaneous Osteoarthritis.
PloS one
Pest MA,Pest CA,Bellini MR,Feng Q,Beier F
Wed Jul 06 00:00:00 EDT 2016
Conditional Deletion of Fgfr3 in Chondrocytes leads to Osteoarthritis-like Defects in Temporomandibular Joint of Adult Mice.
Scientific reports
Zhou S,Xie Y,Li W,Huang J,Wang Z,Tang J,Xu W,Sun X,Tan Q,Huang S,Luo F,Xu M,Wang J,Wu T,Chen L,Chen H,Su N,Du X,Shen Y,Chen L
Mon Apr 04 00:00:00 EDT 2016
Levofloxacin increases apoptosis of rat annulus fibrosus cells via the mechanism of upregulating MMP-2 and MMP-13.
International journal of clinical and experimental medicine
Wei HK,Yang SD,Bai ZL,Zhang X,Yang DL,Ding WY
Wed Feb 17 00:00:00 EST 2016
Conditional knockout of tissue factor pathway inhibitor 2 in vascular endothelial cells accelerates atherosclerotic plaque development in mice.
Thrombosis research
Hong J,Liu R,Chen L,Wu B,Yu J,Gao W,Pan J,Luo X,Shi H
Fri Jan 01 00:00:00 EST 2016
Deletion of Panx3 Prevents the Development of Surgically Induced Osteoarthritis.
Journal of molecular medicine (Berlin, Germany)
Moon PM,Penuela S,Barr K,Khan S,Pin CL,Welch I,Attur M,Abramson SB,Laird DW,Beier F
Sat Aug 01 00:00:00 EDT 2015
Potent effects of dioscin against liver fibrosis.
Scientific reports
Zhang X,Han X,Yin L,Xu L,Qi Y,Xu Y,Sun H,Lin Y,Liu K,Peng J
Wed Apr 08 00:00:00 EDT 2015
17β-estradiol protects against apoptosis induced by interleukin-1β in rat nucleus pulposus cells by down-regulating MMP-3 and MMP-13.
Apoptosis : an international journal on programmed cell death
Yang SD,Yang DL,Sun YP,Wang BL,Ma L,Feng SQ,Ding WY
Sun Mar 01 00:00:00 EST 2015
Protective effects of biochanin A on articular cartilage: in vitro and in vivo studies.
BMC complementary and alternative medicine
Wu DQ,Zhong HM,Ding QH,Ba L
Sat Nov 15 00:00:00 EST 2014
Keratocytes create stromal spaces to promote corneal neovascularization via MMP13 expression.
Investigative ophthalmology & visual science
Ma J,Zhou D,Fan M,Wang H,Huang C,Zhang Z,Wu Y,Li W,Chen Y,Liu Z
Thu Sep 04 00:00:00 EDT 2014
Keratocytes create stromal spaces to promote corneal neovascularization via MMP13 expression.
Investigative ophthalmology & visual science
Ma J,Zhou D,Fan M,Wang H,Huang C,Zhang Z,Wu Y,Li W,Chen Y,Liu Z
Thu Sep 04 00:00:00 EDT 2014
Loss of Vhl in cartilage accelerated the progression of age-associated and surgically induced murine osteoarthritis.
Osteoarthritis and cartilage
Weng T,Xie Y,Yi L,Huang J,Luo F,Du X,Chen L,Liu C,Chen D,Chen L
Fri Aug 01 00:00:00 EDT 2014
Chondroprotective effects and multi-target mechanisms of Icariin in IL-1 beta-induced human SW 1353 chondrosarcoma cells and a rat osteoarthritis model.
International immunopharmacology
Zeng L,Wang W,Rong XF,Zhong Y,Jia P,Zhou GQ,Li RH
Wed Jan 01 00:00:00 EST 2014
Celastrol, an inhibitor of heat shock protein 90β potently suppresses the expression of matrix metalloproteinases, inducible nitric oxide synthase and cyclooxygenase-2 in primary human osteoarthritic chondrocytes.
European journal of pharmacology
Ding QH,Cheng Y,Chen WP,Zhong HM,Wang XH
Wed May 15 00:00:00 EDT 2013
Suppression of hyaluronan synthesis alleviates inflammatory responses in murine arthritis and in human rheumatoid synovial fibroblasts.
Arthritis and rheumatism
Yoshioka Y,Kozawa E,Urakawa H,Arai E,Futamura N,Zhuo L,Kimata K,Ishiguro N,Nishida Y
Wed May 01 00:00:00 EDT 2013
Anti-arthritic effects of crocin in interleukin-1β-treated articular chondrocytes and cartilage in a rabbit osteoarthritic model.
Inflammation research : official journal of the European Histamine Research Society ... [et al.]
Ding Q,Zhong H,Qi Y,Cheng Y,Li W,Yan S,Wang X
Tue Jan 01 00:00:00 EST 2013
Genetic inhibition of fibroblast growth factor receptor 1 in knee cartilage attenuates the degeneration of articular cartilage in adult mice.
Arthritis and rheumatism
Weng T,Yi L,Huang J,Luo F,Wen X,Du X,Chen Q,Deng C,Chen D,Chen L
Sat Dec 01 00:00:00 EST 2012
Genetic inhibition of fibroblast growth factor receptor 1 in knee cartilage attenuates the degeneration of articular cartilage in adult mice.
Arthritis and rheumatism
Weng T,Yi L,Huang J,Luo F,Wen X,Du X,Chen Q,Deng C,Chen D,Chen L
Sat Dec 01 00:00:00 EST 2012