Product References
WITHDRAWN: Expression of Tmem41b and MMP13 associated with poor outcome in osteosarcomas.
Neoplasma
Li GH,Liu X,Feng LJ,Zhang L
Sun Aug 20 00:00:00 UTC 2023
Preparation of Melatonin-Loaded Nanoparticles with Targeting and Sustained Release Function and Their Application in Osteoarthritis.
International journal of molecular sciences
Liang H,Yan Y,Sun W,Ma X,Su Z,Liu Z,Chen Y,Yu B
Sun May 14 00:00:00 UTC 2023
Preparation of Melatonin-Loaded Nanoparticles with Targeting and Sustained Release Function and Their Application in Osteoarthritis.
International journal of molecular sciences
Liang H,Yan Y,Sun W,Ma X,Su Z,Liu Z,Chen Y,Yu B
Sun May 14 00:00:00 UTC 2023
Cyasterone inhibits IL-1β-mediated apoptosis and inflammation via the NF-κB and MAPK signaling pathways in rat chondrocytes and ameliorates osteoarthritisin vivo.
Chinese journal of natural medicines
Teng L,Shen Y,Qu Y,Yang L,Yang Y,Jian X,Fan S,Zhang L,Fu Q
Wed Feb 01 00:00:00 UTC 2023
Maintaining hypoxia environment of subchondral bone alleviates osteoarthritis progression.
Science advances
Zhang H,Wang L,Cui J,Wang S,Han Y,Shao H,Wang C,Hu Y,Li X,Zhou Q,Guo J,Zhuang X,Sheng S,Zhang T,Zhou D,Chen J,Wang F,Gao Q,Jing Y,Chen X,Su J
Wed Apr 05 00:00:00 UTC 2023
Stevioside protects primary articular chondrocytes against IL-1β-induced inflammation and catabolism by targeting integrin.
International immunopharmacology
Wan J,Zhu Z,He Z,Wu H,Chen A,Zhu W,Cheng P
Thu Jun 01 00:00:00 UTC 2023
Intra-articular treatment of temporomandibular joint osteoarthritis by injecting actively-loaded meloxicam liposomes with dual-functions of anti-inflammation and lubrication.
Materials today. Bio
Zhong Y,Zhou Y,Ding R,Zou L,Zhang H,Wei X,He D
Sat Apr 01 00:00:00 UTC 2023
Cardamonin alleviates chondrocytes inflammation and cartilage degradation of osteoarthritis by inhibiting ferroptosis via p53 pathway.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Gong Z,Wang Y,Li L,Li X,Qiu B,Hu Y
Sat Apr 01 00:00:00 UTC 2023
Down-regulated GAS6 impairs synovial macrophage efferocytosis and promotes obesity-associated osteoarthritis.
eLife
Yao Z,Qi W,Zhang H,Zhang Z,Liu L,Shao Y,Zeng H,Yin J,Pan H,Guo X,Liu A,Cai D,Bai X,Zhang H
Fri May 05 00:00:00 UTC 2023
Indole-3-propionic acid alleviates chondrocytes inflammation and osteoarthritis via the AhR/NF-κB axis.
Molecular medicine (Cambridge, Mass.)
Zhuang H,Ren X,Jiang F,Zhou P
Tue Jan 31 00:00:00 UTC 2023
Indole-3-propionic acid alleviates chondrocytes inflammation and osteoarthritis via the AhR/NF-κB axis.
Molecular medicine (Cambridge, Mass.)
Zhuang H,Ren X,Jiang F,Zhou P
Tue Jan 31 00:00:00 UTC 2023
pH-Responsive Delivery of H2 through Ammonia Borane-Loaded Hollow Polydopamine for Intervertebral Disc Degeneration Therapy.
Oxidative medicine and cellular longevity
Wang W,Xiao B,Qiu Y,Liu Y,Tang G,Deng G,Xi Y,Xu G,Wang Y
Tue Feb 14 00:00:00 UTC 2023
The Role of the miR-548au-3p/CA12 Axis in Tracheal Chondrogenesis in Congenital Pulmonary Airway Malformations.
Oxidative medicine and cellular longevity
Zeng J,Zhang X,Yang Q,Peng J,Wang F,Tang J,Xu Y,Huang D,Liang J,Li L
Thu Mar 02 00:00:00 UTC 2023
Excess Growth Hormone Triggers Inflammation-Associated Arthropathy, Subchondral Bone Loss, and Arthralgia.
The American journal of pathology
Poudel SB,Ruff RR,Yildirim G,Dixit M,Michot B,Gibbs JL,Ortiz SD,Kopchick JJ,Kirsch T,Yakar S
Thu Jun 01 00:00:00 UTC 2023
Orientin inhibits inflammation in chondrocytes and attenuates osteoarthritis through Nrf2/NF-κB and SIRT6/NF-κB pathway.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society
Xia W,Xiao J,Tong C,Lu J,Tu Y,Li S,Ni L,Shi Y,Luo P,Zhang X,Wang X
Wed Nov 01 00:00:00 UTC 2023
An injectable liposome-anchored teriparatide incorporated gallic acid-grafted gelatin hydrogel for osteoarthritis treatment.
Nature communications
Li G,Liu S,Chen Y,Zhao J,Xu H,Weng J,Yu F,Xiong A,Udduttula A,Wang D,Liu P,Chen Y,Zeng H
Wed May 31 00:00:00 UTC 2023
Novel insights into the effect of deer IGF-1 on chondrocyte viability and IL-1β-induced inflammation response.
Journal of biochemical and molecular toxicology
Zhong J,Zhang J,Zhou Z,Pan D,Zhao D,Dong H,Yao B
Sun Jan 01 00:00:00 UTC 2023
Monotropein attenuates apoptosis and pyroptosis in chondrocytes and alleviates osteoarthritis progression in mice.
Chinese medicine
Li Z,Chen Z,Chen J,Liu Z,Li Z,Sun H,Wang X,Wei J,Cao X,Zheng D
Wed Apr 19 00:00:00 UTC 2023
Monotropein attenuates apoptosis and pyroptosis in chondrocytes and alleviates osteoarthritis progression in mice.
Chinese medicine
Li Z,Chen Z,Chen J,Liu Z,Li Z,Sun H,Wang X,Wei J,Cao X,Zheng D
Wed Apr 19 00:00:00 UTC 2023
BACH1 promotes intervertebral disc degeneration by regulating HMOX1/GPX4 to mediate oxidative stress, ferroptosis, and lipid metabolism in nucleus pulposus cells.
The journal of gene medicine
Yao B,Cai Y,Wan L,Deng J,Zhao L,Wang W,Han Z
Thu Jun 01 00:00:00 UTC 2023
Physalin A alleviates intervertebral disc degeneration via anti-inflammatory and anti-fibrotic effects.
Journal of orthopaedic translation
Lu R,Xu H,Deng X,Wang Y,He Z,Xu S,Liang S,Huang X,You H,Guo F,Cheng P,Chen AM
Wed Mar 01 00:00:00 UTC 2023
Physalin A alleviates intervertebral disc degeneration via anti-inflammatory and anti-fibrotic effects.
Journal of orthopaedic translation
Lu R,Xu H,Deng X,Wang Y,He Z,Xu S,Liang S,Huang X,You H,Guo F,Cheng P,Chen AM
Wed Mar 01 00:00:00 UTC 2023
Physalin A alleviates intervertebral disc degeneration via anti-inflammatory and anti-fibrotic effects.
Journal of orthopaedic translation
Lu R,Xu H,Deng X,Wang Y,He Z,Xu S,Liang S,Huang X,You H,Guo F,Cheng P,Chen AM
Wed Mar 01 00:00:00 UTC 2023
N-acetylglucosamine-bearing polymers mimicking O-GlcNAc-modified proteins elicit anti-fibrotic activities in myofibroblasts and activated stellate cells.
Glycobiology
Ise H,Araki Y,Song I,Akatsuka G
Sun Jan 08 00:00:00 UTC 2023
PTEN inhibitor VO-OHpic protects endplate chondrocytes against apoptosis and calcification via activating Nrf-2 signaling pathway.
Aging
Cui X,Liu X,Kong P,Du T,Li T,Yang G,Zhang W,Jing X,Wang W
Fri Mar 24 00:00:00 UTC 2023
Knockdown of LINC01138 protects human chondrocytes against IL-1β-induced damage by regulating the hsa-miR-1207-5p/KIAA0101 axis.
Immunity, inflammation and disease
Zhang J,Lv G
Sun Jan 01 00:00:00 UTC 2023
Astaxanthin suppresses oxidative stress and calcification in vertebral cartilage endplate via activating Nrf-2/HO-1 signaling pathway.
International immunopharmacology
Yang G,Liu X,Jing X,Wang J,Wang H,Chen F,Wang W,Shao Y,Cui X
Thu Jun 01 00:00:00 UTC 2023
Docosahexaenoic acid alleviates the excessive degradation of extracellular matrix in the nucleus pulposus by reducing the content of lncRNA NEAT1 to prevent the progression of intervertebral disc degeneration.
Clinical and experimental pharmacology & physiology
Shang L,Ma H,Zhang X,Mao R,Ma C,Ruan Z
Mon May 01 00:00:00 UTC 2023
Docosahexaenoic acid alleviates the excessive degradation of extracellular matrix in the nucleus pulposus by reducing the content of lncRNA NEAT1 to prevent the progression of intervertebral disc degeneration.
Clinical and experimental pharmacology & physiology
Shang L,Ma H,Zhang X,Mao R,Ma C,Ruan Z
Mon May 01 00:00:00 UTC 2023
Thermosensitive hydrogel for cartilage regeneration via synergistic delivery of SDF-1α like polypeptides and kartogenin.
Carbohydrate polymers
Yuan X,Wan J,Yang Y,Huang L,Zhou C,Su J,Hua S,Pu H,Zou Y,Zhu H,Jiang X,Xiao J
Wed Mar 15 00:00:00 UTC 2023
IL16 Regulates Osteoarthritis Progression as a Target Gene of Novel-miR-81.
Cartilage
Luo Z,Han Q,Lu J,Ouyang X,Fan Y,Liu Y,Zhou X,Kong J,Liu H,Liu A,Chen D
Fri Apr 21 00:00:00 UTC 2023
Isobavachalcone ameliorates the progression of osteoarthritis by suppressing NF-κB signaling pathway.
International immunopharmacology
Guo Q,Zhang M,Dong Y,Liu K,Wang D,Zheng J
Thu Jun 01 00:00:00 UTC 2023
Isobavachalcone ameliorates the progression of osteoarthritis by suppressing NF-κB signaling pathway.
International immunopharmacology
Guo Q,Zhang M,Dong Y,Liu K,Wang D,Zheng J
Thu Jun 01 00:00:00 UTC 2023
LncRNA WDR11-AS1 Promotes Extracellular Matrix Synthesis in Osteoarthritis by Directly Interacting with RNA-Binding Protein PABPC1 to Stabilize SOX9 Expression.
International journal of molecular sciences
Huang H,Yan J,Lan X,Guo Y,Sun M,Zhao Y,Zhang F,Sun J,Lu S
Tue Jan 03 00:00:00 UTC 2023
LncRNA WDR11-AS1 Promotes Extracellular Matrix Synthesis in Osteoarthritis by Directly Interacting with RNA-Binding Protein PABPC1 to Stabilize SOX9 Expression.
International journal of molecular sciences
Huang H,Yan J,Lan X,Guo Y,Sun M,Zhao Y,Zhang F,Sun J,Lu S
Tue Jan 03 00:00:00 UTC 2023
METTL3 promotes SMSCs chondrogenic differentiation by targeting the MMP3, MMP13, and GATA3.
Regenerative therapy
Hu B,Zou X,Yu Y,Jiang Y,Xu H
Wed Mar 01 00:00:00 UTC 2023
Hypoxia-Inducible Factor-1α Protects Against Intervertebral Disc Degeneration Through Antagonizing Mitochondrial Oxidative Stress.
Inflammation
Yang W,Jia C,Liu L,Fu Y,Wu Y,Liu Z,Yu R,Ma X,Gong A,Liu F,Xia Y,Hou Y,Li Y,Zhang L
Wed Feb 01 00:00:00 UTC 2023
Hypoxia-Inducible Factor-1α Protects Against Intervertebral Disc Degeneration Through Antagonizing Mitochondrial Oxidative Stress.
Inflammation
Yang W,Jia C,Liu L,Fu Y,Wu Y,Liu Z,Yu R,Ma X,Gong A,Liu F,Xia Y,Hou Y,Li Y,Zhang L
Wed Feb 01 00:00:00 UTC 2023
Apigenin Inhibits the Progression of Osteoarthritis by Mediating Macrophage Polarization.
Molecules (Basel, Switzerland)
Ji X,Du W,Che W,Wang L,Zhao L
Fri Mar 24 00:00:00 UTC 2023
Platelet-derived extracellular vesicles ameliorate intervertebral disc degeneration by alleviating mitochondrial dysfunction.
Materials today. Bio
Dai Z,Xia C,Zhao T,Wang H,Tian H,Xu O,Zhu X,Zhang J,Chen P
Wed Feb 01 00:00:00 UTC 2023
Platelet-derived extracellular vesicles ameliorate intervertebral disc degeneration by alleviating mitochondrial dysfunction.
Materials today. Bio
Dai Z,Xia C,Zhao T,Wang H,Tian H,Xu O,Zhu X,Zhang J,Chen P
Wed Feb 01 00:00:00 UTC 2023
Platelet-derived extracellular vesicles ameliorate intervertebral disc degeneration by alleviating mitochondrial dysfunction.
Materials today. Bio
Dai Z,Xia C,Zhao T,Wang H,Tian H,Xu O,Zhu X,Zhang J,Chen P
Wed Feb 01 00:00:00 UTC 2023
Platelet-derived extracellular vesicles ameliorate intervertebral disc degeneration by alleviating mitochondrial dysfunction.
Materials today. Bio
Dai Z,Xia C,Zhao T,Wang H,Tian H,Xu O,Zhu X,Zhang J,Chen P
Wed Feb 01 00:00:00 UTC 2023
Integrated Cascade Nanozyme Remodels Chondrocyte Inflammatory Microenvironment in Temporomandibular Joint Osteoarthritis via Inhibiting ROS-NF-κB and MAPK Pathways.
Advanced healthcare materials
Zhang Z,Yuan L,Liu Y,Wang R,Zhang Y,Yang Y,Wei H,Ma J
Sat Apr 01 00:00:00 UTC 2023
Hepatic TREM2+ macrophages express matrix metalloproteinases to control fibrotic scar formation.
Immunology and cell biology
Lee KJ,An S,Kim MY,Kim SM,Jeong WI,Ko HJ,Yang YM,Noh M,Han YH
Wed Mar 01 00:00:00 UTC 2023
Suramin ameliorates osteoarthritis by acting on the Nrf2/HO-1 and NF-κB signaling pathways in chondrocytes and promoting M2 polarization in macrophages.
International immunopharmacology
Shen PC,Huang SH,Liu ZM,Lu CC,Chou SH,Tien YC
Sat Jul 01 00:00:00 UTC 2023
Methyl gallate prevents oxidative stress induced apoptosis and ECM degradation in chondrocytes via restoring Sirt3 mediated autophagy and ameliorates osteoarthritis progression.
International immunopharmacology
Li Y,Shen B,Lv C,Zhu X,Naren Q,Xu D,Chen H,Wu F
Sun Jan 01 00:00:00 UTC 2023
Methyl gallate prevents oxidative stress induced apoptosis and ECM degradation in chondrocytes via restoring Sirt3 mediated autophagy and ameliorates osteoarthritis progression.
International immunopharmacology
Li Y,Shen B,Lv C,Zhu X,Naren Q,Xu D,Chen H,Wu F
Sun Jan 01 00:00:00 UTC 2023
The Effect of Gut Microbiota on the Progression of Intervertebral Disc Degeneration.
Orthopaedic surgery
Yao B,Cai Y,Wang W,Deng J,Zhao L,Han Z,Wan L
Wed Mar 01 00:00:00 UTC 2023
Hederagenin Suppresses Inflammation and Cartilage Degradation to Ameliorate the Progression of Osteoarthritis: An In vivo and In vitro Study.
Inflammation
Shen Y,Teng L,Qu Y,Huang Y,Peng Y,Tang M,Fu Q
Sat Apr 01 00:00:00 UTC 2023
Hederagenin Suppresses Inflammation and Cartilage Degradation to Ameliorate the Progression of Osteoarthritis: An In vivo and In vitro Study.
Inflammation
Shen Y,Teng L,Qu Y,Huang Y,Peng Y,Tang M,Fu Q
Sat Apr 01 00:00:00 UTC 2023
Therapeutic Effect of Acupotomy at Sanheyang for Cartilage Collagen Damage in Moderate Knee Osteoarthritis: A Rabbit Model.
Journal of inflammation research
Li Y,Hou Y,Sun J,Wei J,Chai Y,Guo M,Wang R
Thu Jun 01 00:00:00 UTC 2023
Dendrobine Alleviates Cellular Senescence and Osteoarthritis via the ROS/NF-κB Axis.
International journal of molecular sciences
Chen H,Tu M,Liu S,Wen Y,Chen L
Wed Jan 25 00:00:00 UTC 2023
Dendrobine Alleviates Cellular Senescence and Osteoarthritis via the ROS/NF-κB Axis.
International journal of molecular sciences
Chen H,Tu M,Liu S,Wen Y,Chen L
Wed Jan 25 00:00:00 UTC 2023
Dendrobine Alleviates Cellular Senescence and Osteoarthritis via the ROS/NF-κB Axis.
International journal of molecular sciences
Chen H,Tu M,Liu S,Wen Y,Chen L
Wed Jan 25 00:00:00 UTC 2023
Ginsenoside Compound K Ameliorates Osteoarthritis by Inhibiting the Chondrocyte Endoplasmic Reticulum Stress-Mediated IRE1α-TXNIP-NLRP3 Axis and Pyroptosis.
Journal of agricultural and food chemistry
Tian Y,Feng X,Zhou Z,Qin S,Chen S,Zhao J,Hou J,Liu D
Wed Jan 25 00:00:00 UTC 2023
Ginsenoside Compound K Ameliorates Osteoarthritis by Inhibiting the Chondrocyte Endoplasmic Reticulum Stress-Mediated IRE1α-TXNIP-NLRP3 Axis and Pyroptosis.
Journal of agricultural and food chemistry
Tian Y,Feng X,Zhou Z,Qin S,Chen S,Zhao J,Hou J,Liu D
Wed Jan 25 00:00:00 UTC 2023
Dioscin alleviates the progression of osteoarthritis: an in vitro and in vivo study.
Journal of inflammation (London, England)
Ding Q,Zhang R,Sheng G,Wang T,Jing S,Ma T,Wang S,Zhao H,Wu H,Li W
Thu Apr 13 00:00:00 UTC 2023
Dioscin alleviates the progression of osteoarthritis: an in vitro and in vivo study.
Journal of inflammation (London, England)
Ding Q,Zhang R,Sheng G,Wang T,Jing S,Ma T,Wang S,Zhao H,Wu H,Li W
Thu Apr 13 00:00:00 UTC 2023
SIRT5-related desuccinylation modification of AIFM1 protects against compression-induced intervertebral disc degeneration by regulating mitochondrial homeostasis.
Experimental & molecular medicine
Mao J,Wang D,Wang D,Wu Q,Shang Q,Gao C,Wang H,Wang H,Du M,Peng P,Jia H,Xu X,Wang J,Yang L,Luo Z
Sun Jan 01 00:00:00 UTC 2023
SIRT5-related desuccinylation modification of AIFM1 protects against compression-induced intervertebral disc degeneration by regulating mitochondrial homeostasis.
Experimental & molecular medicine
Mao J,Wang D,Wang D,Wu Q,Shang Q,Gao C,Wang H,Wang H,Du M,Peng P,Jia H,Xu X,Wang J,Yang L,Luo Z
Sun Jan 01 00:00:00 UTC 2023
SIRT5-related desuccinylation modification of AIFM1 protects against compression-induced intervertebral disc degeneration by regulating mitochondrial homeostasis.
Experimental & molecular medicine
Mao J,Wang D,Wang D,Wu Q,Shang Q,Gao C,Wang H,Wang H,Du M,Peng P,Jia H,Xu X,Wang J,Yang L,Luo Z
Sun Jan 01 00:00:00 UTC 2023
SIRT5-related desuccinylation modification of AIFM1 protects against compression-induced intervertebral disc degeneration by regulating mitochondrial homeostasis.
Experimental & molecular medicine
Mao J,Wang D,Wang D,Wu Q,Shang Q,Gao C,Wang H,Wang H,Du M,Peng P,Jia H,Xu X,Wang J,Yang L,Luo Z
Sun Jan 01 00:00:00 UTC 2023
Luteolin ameliorates cornea stromal collagen degradation and inflammatory damage in rats with corneal alkali burn.
Experimental eye research
Wang H,Guo Z,Liu P,Yang X,Li Y,Lin Y,Zhao X,Liu Y
Thu Jun 01 00:00:00 UTC 2023
hASCs-derived exosomal miR-155-5p targeting TGFβR2 promotes autophagy and reduces pyroptosis to alleviate intervertebral disc degeneration.
Journal of orthopaedic translation
Chen D,Jiang X,Zou H
Wed Mar 01 00:00:00 UTC 2023
The Bcr-Abl inhibitor DCC-2036 inhibits necroptosis and ameliorates osteoarthritis by targeting RIPK1 and RIPK3 kinases.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Piao L,Wu D,Rui C,Yang Y,Liu S,Liu J,Jin Z,Zhang H,Feng X,Bai L
Mon May 01 00:00:00 UTC 2023
The Bcr-Abl inhibitor DCC-2036 inhibits necroptosis and ameliorates osteoarthritis by targeting RIPK1 and RIPK3 kinases.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Piao L,Wu D,Rui C,Yang Y,Liu S,Liu J,Jin Z,Zhang H,Feng X,Bai L
Mon May 01 00:00:00 UTC 2023
1,25-Dihydroxyvitamin D Deficiency Accelerates Aging-related Osteoarthritis via Downregulation of Sirt1 in Mice.
International journal of biological sciences
Chen J,Zhang J,Li J,Qin R,Lu N,Goltzman D,Miao D,Yang R
Thu Feb 09 00:00:00 UTC 2023
Inhibition of Klf10 Attenuates Oxidative Stress-Induced Senescence of Chondrocytes via Modulating Mitophagy.
Molecules (Basel, Switzerland)
Shang J,Lin N,Peng R,Jiang N,Wu B,Xing B,Lin S,Xu X,Lu H
Tue Jan 17 00:00:00 UTC 2023
ROS-responsive magnesium-containing microspheres for antioxidative treatment of intervertebral disc degeneration.
Acta biomaterialia
Zhang T,Wang Y,Li R,Xin J,Zheng Z,Zhang X,Xiao C,Zhang S
Wed Mar 01 00:00:00 UTC 2023
Pan-cancer analysis reveals the associations between MMP13 high expression and carcinogenesis and its value as a serum diagnostic marker.
Aging
Zhang X,Deng Q,Wan X,Zhao J,Zheng X,Wang H,Wang HQ,Yang W
Wed Mar 22 00:00:00 UTC 2023
Analyses of Transcriptomics upon IL-1β-Stimulated Mouse Chondrocytes and the Protective Effect of Catalpol through the NOD2/NF-κB/MAPK Signaling Pathway.
Molecules (Basel, Switzerland)
Pang Y,Zhao L,Ji X,Guo K,Yin X
Tue Feb 07 00:00:00 UTC 2023
Type 1 diabetes mellitus leads to gingivitis and an early compensatory increase in bone remodeling.
Journal of periodontology
Yuan X,Amin V,Zhu T,Kittaka M,Ueki Y,Bellido TM,Turkkahraman H
Wed Feb 01 00:00:00 UTC 2023
The Protective Effect of Selenium Nanoparticles in Osteoarthritis: In vitro and in vivo Studies.
Drug design, development and therapy
Li Y,Zhu S,Luo J,Tong Y,Zheng Y,Ji L,He Z,Jing Q,Huang J,Zhang Y,Bi Q
Thu Jun 01 00:00:00 UTC 2023
The Protective Effect of Selenium Nanoparticles in Osteoarthritis: In vitro and in vivo Studies.
Drug design, development and therapy
Li Y,Zhu S,Luo J,Tong Y,Zheng Y,Ji L,He Z,Jing Q,Huang J,Zhang Y,Bi Q
Thu Jun 01 00:00:00 UTC 2023
The Protective Effect of Selenium Nanoparticles in Osteoarthritis: In vitro and in vivo Studies.
Drug design, development and therapy
Li Y,Zhu S,Luo J,Tong Y,Zheng Y,Ji L,He Z,Jing Q,Huang J,Zhang Y,Bi Q
Thu Jun 01 00:00:00 UTC 2023
Mulberroside A alleviates osteoarthritis via restoring impaired autophagy and suppressing MAPK/NF-κB/PI3K-AKT-mTOR signaling pathways.
iScience
Lu R,Wei Z,Wang Z,Xu S,Sun K,Cheng P,Huang X,You H,Guo F,Liang S,Chen AM
Fri Feb 17 00:00:00 UTC 2023
Mulberroside A alleviates osteoarthritis via restoring impaired autophagy and suppressing MAPK/NF-κB/PI3K-AKT-mTOR signaling pathways.
iScience
Lu R,Wei Z,Wang Z,Xu S,Sun K,Cheng P,Huang X,You H,Guo F,Liang S,Chen AM
Fri Feb 17 00:00:00 UTC 2023
Transglutaminase 2 inhibitors attenuate osteoarthritic degeneration of TMJ-osteoarthritis by suppressing NF-κB activation.
International immunopharmacology
Li Y,Sun H,Liu X,Hu Z,Jiang H,Guo H,Long X
Sun Jan 01 00:00:00 UTC 2023
Transglutaminase 2 inhibitors attenuate osteoarthritic degeneration of TMJ-osteoarthritis by suppressing NF-κB activation.
International immunopharmacology
Li Y,Sun H,Liu X,Hu Z,Jiang H,Guo H,Long X
Sun Jan 01 00:00:00 UTC 2023
Transglutaminase 2 inhibitors attenuate osteoarthritic degeneration of TMJ-osteoarthritis by suppressing NF-κB activation.
International immunopharmacology
Li Y,Sun H,Liu X,Hu Z,Jiang H,Guo H,Long X
Sun Jan 01 00:00:00 UTC 2023
Transglutaminase 2 inhibitors attenuate osteoarthritic degeneration of TMJ-osteoarthritis by suppressing NF-κB activation.
International immunopharmacology
Li Y,Sun H,Liu X,Hu Z,Jiang H,Guo H,Long X
Sun Jan 01 00:00:00 UTC 2023
Therapeutic effects of kefir peptides on adjuvant-induced arthritis in rats through anti-inflammation and downregulation of matrix metalloproteinases.
Life sciences
Chuang KC,Lai YW,Ko CH,Yen CC,Chen HL,Lan YW,Chen CF,Chen W,Chen CM
Wed Mar 15 00:00:00 UTC 2023
Sirt1 protects against intervertebral disc degeneration induced by 1,25-dihydroxyvitamin D insufficiency in mice by inhibiting the NF-κB inflammatory pathway.
Journal of orthopaedic translation
Wang P,Yang C,Lu J,Ren Y,Goltzman D,Miao D
Mon May 01 00:00:00 UTC 2023
Sirt1 protects against intervertebral disc degeneration induced by 1,25-dihydroxyvitamin D insufficiency in mice by inhibiting the NF-κB inflammatory pathway.
Journal of orthopaedic translation
Wang P,Yang C,Lu J,Ren Y,Goltzman D,Miao D
Mon May 01 00:00:00 UTC 2023
Sirt1 protects against intervertebral disc degeneration induced by 1,25-dihydroxyvitamin D insufficiency in mice by inhibiting the NF-κB inflammatory pathway.
Journal of orthopaedic translation
Wang P,Yang C,Lu J,Ren Y,Goltzman D,Miao D
Mon May 01 00:00:00 UTC 2023
miR-140-5p protects cartilage progenitor/stem cells from fate changes in knee osteoarthritis.
International immunopharmacology
Chen Y,Huang H,Zhong W,Li L,Lu Y,Si HB
Sun Jan 01 00:00:00 UTC 2023
Polydopamine-Pd nanozymes as potent ROS scavengers in combination with near-infrared irradiation for osteoarthritis treatment.
iScience
Hu H,Yang J,Zhong Y,Wang J,Cai J,Luo C,Jin Z,Gao M,He M,Zheng L
Fri May 19 00:00:00 UTC 2023
Treadmill Exercise Suppresses Histological Progression of Disuse Atrophy in Articular Cartilage in Rat Knee Joints during Hindlimb Suspension.
Cartilage
Takahashi I,Matsuzaki T,Kuroki H,Hoso M
Fri Dec 01 00:00:00 UTC 2023
Circular RNA SLTM as a miR-421-competing endogenous RNA to mediate HMGB2 expression stimulates apoptosis and inflammation in arthritic chondrocytes.
Journal of biochemical and molecular toxicology
Zhang H,Xiang X,Zhou B,Chen J,Sun Y,Zhang S,Li A,Li J
Mon May 01 00:00:00 UTC 2023
Caffeic acid phenethyl ester attenuates osteoarthritis progression by activating NRF2/HO‑1 and inhibiting the NF‑κB signaling pathway.
International journal of molecular medicine
Sun W,Xie W,Huang D,Cui Y,Yue J,He Q,Jiang L,Xiong J,Sun W,Yi Q
Tue Nov 01 00:00:00 UTC 2022
Caffeic acid phenethyl ester attenuates osteoarthritis progression by activating NRF2/HO‑1 and inhibiting the NF‑κB signaling pathway.
International journal of molecular medicine
Sun W,Xie W,Huang D,Cui Y,Yue J,He Q,Jiang L,Xiong J,Sun W,Yi Q
Tue Nov 01 00:00:00 UTC 2022
Dual functions of microRNA-17 in maintaining cartilage homeostasis and protection against osteoarthritis.
Nature communications
Zhang Y,Li S,Jin P,Shang T,Sun R,Lu L,Guo K,Liu J,Tong Y,Wang J,Liu S,Wang C,Kang Y,Zhu W,Wang Q,Zhang X,Yin F,Sun YE,Cui L
Wed May 04 00:00:00 UTC 2022
Dual functions of microRNA-17 in maintaining cartilage homeostasis and protection against osteoarthritis.
Nature communications
Zhang Y,Li S,Jin P,Shang T,Sun R,Lu L,Guo K,Liu J,Tong Y,Wang J,Liu S,Wang C,Kang Y,Zhu W,Wang Q,Zhang X,Yin F,Sun YE,Cui L
Wed May 04 00:00:00 UTC 2022
Corynoline Alleviates Osteoarthritis Development via the Nrf2/NF-κB Pathway.
Oxidative medicine and cellular longevity
Li S,Shi Y,Zhang S,Li H,Ye Z,Kong J,Hong W,Tu Y,Ren J,Meftah Z,Xie C,Wang X,Zhang X
Wed Aug 10 00:00:00 UTC 2022
Tangeretin suppresses osteoarthritis progression via the Nrf2/NF-κB and MAPK/NF-κB signaling pathways.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Shi Y,Chen J,Li S,Wu Y,Yu C,Ni L,Xiao J,Shao Z,Zhu H,Wang J,Wang X,Zhang X
Fri Apr 01 00:00:00 UTC 2022
Tangeretin suppresses osteoarthritis progression via the Nrf2/NF-κB and MAPK/NF-κB signaling pathways.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Shi Y,Chen J,Li S,Wu Y,Yu C,Ni L,Xiao J,Shao Z,Zhu H,Wang J,Wang X,Zhang X
Fri Apr 01 00:00:00 UTC 2022
Tangeretin suppresses osteoarthritis progression via the Nrf2/NF-κB and MAPK/NF-κB signaling pathways.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Shi Y,Chen J,Li S,Wu Y,Yu C,Ni L,Xiao J,Shao Z,Zhu H,Wang J,Wang X,Zhang X
Fri Apr 01 00:00:00 UTC 2022
Periostin promotes nucleus pulposus cells apoptosis by activating the Wnt/β-catenin signaling pathway.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Zhu D,Wang Z,Zhang G,Ma C,Qiu X,Wang Y,Liu M,Guo X,Chen H,Deng Q,Kang X
Fri Jul 01 00:00:00 UTC 2022
SKI knockdown suppresses apoptosis and extracellular matrix degradation of nucleus pulposus cells via inhibition of the Wnt/β-catenin pathway and ameliorates disc degeneration.
Apoptosis : an international journal on programmed cell death
Wu ZL,Chen YJ,Zhang GZ,Xie QQ,Wang KP,Yang X,Liu TC,Wang ZQ,Zhao GH,Zhang HH
Tue Feb 01 00:00:00 UTC 2022
Gastrocnemius Muscle Injury Is the Condition to Induce Cartilage Degeneration of the Rabbit Tibiofemoral Joint: A New Perspective.
BioMed research international
Li Y,Sun J,Hou Y,Wei J,Chai Y,Zhu X,Wang R
Tue Sep 13 00:00:00 UTC 2022
Nodakenin attenuates cartilage degradation and inflammatory responses in a mice model of knee osteoarthritis by regulating mitochondrial Drp1/ROS/NLRP3 axis.
International immunopharmacology
Yi N,Mi Y,Xu X,Li N,Chen B,Yan K,Tan K,Zhang B,Wang L,Kuang G,Lu M
Thu Dec 01 00:00:00 UTC 2022
Nodakenin attenuates cartilage degradation and inflammatory responses in a mice model of knee osteoarthritis by regulating mitochondrial Drp1/ROS/NLRP3 axis.
International immunopharmacology
Yi N,Mi Y,Xu X,Li N,Chen B,Yan K,Tan K,Zhang B,Wang L,Kuang G,Lu M
Thu Dec 01 00:00:00 UTC 2022
Inhibition of HMGB1 suppresses inflammation and catabolism in temporomandibular joint osteoarthritis via NF-κB signaling pathway.
European journal of histochemistry : EJH
Li YY,Feng YP,Liu L,Ke J,Long X
Tue Jun 21 00:00:00 UTC 2022
Inhibition of HMGB1 suppresses inflammation and catabolism in temporomandibular joint osteoarthritis via NF-κB signaling pathway.
European journal of histochemistry : EJH
Li YY,Feng YP,Liu L,Ke J,Long X
Tue Jun 21 00:00:00 UTC 2022
Spheroid Formation Enhances the Regenerative Capacity of Nucleus Pulposus Cells via Regulating N-CDH and ITGβ1 Interaction.
International journal of biological sciences
Wang Y,Wang H,Zhuo Y,Hu Y,Li X,Xu Y,Sun B,Liu M,Zou L,Liu L,Luo L,Zhao C,Li P,Zhou Q
Tue Jul 12 00:00:00 UTC 2022
CD40/TRAF1 decreases synovial cell apoptosis in patients with rheumatoid arthritis through JNK/NF-κB pathway.
Journal of bone and mineral metabolism
Cheng T,Wu J,Xu Y,Liu C,Zhang H,Wang M
Thu Sep 01 00:00:00 UTC 2022
Transcriptomic analysis supports collective endometrial cell migration in the pathogenesis of adenomyosis.
Reproductive biomedicine online
Zhai J,Li S,Sen S,Vallvé-Juanico J,Irwin JC,Vo KC,Wan J,Du Y,Chen ZJ,Giudice LC
Thu Sep 01 00:00:00 UTC 2022
Elevation of α-1,3 fucosylation promotes the binding ability of TNFR1 to TNF-α and contributes to osteoarthritic cartilage destruction and apoptosis.
Arthritis research & therapy
Yu H,Li M,Wen X,Yang J,Liang X,Li X,Bao X,Shu J,Ren X,Chen W,Li Z,Li Y
Fri Apr 29 00:00:00 UTC 2022
Icariin protects vertebral endplate chondrocytes against apoptosis and degeneration via activating Nrf-2/HO-1 pathway.
Frontiers in pharmacology
Shao Y,Sun L,Yang G,Wang W,Liu X,Du T,Chen F,Jing X,Cui X
Sat Oct 01 00:00:00 UTC 2022
Gaseous signal molecule SO2 regulates autophagy through PI3K/AKT pathway inhibits cardiomyocyte apoptosis and improves myocardial fibrosis in rats with type II diabetes.
The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology
Zhao J,Wu Q,Yang T,Nie L,Liu S,Zhou J,Chen J,Jiang Z,Xiao T,Yang J,Chu C
Tue Nov 01 00:00:00 UTC 2022
Saikosaponin D Inhibited IL-1β Induced ATDC 5 Chondrocytes Apoptosis In Vitro and Delayed Articular Cartilage Degeneration in OA Model Mice In Vivo.
Frontiers in pharmacology
Wu X,Zhao K,Fang X,Lu F,Cheng P,Song X,Zhang W,Yao C,Zhu J,Chen H
Tue Apr 05 00:00:00 UTC 2022
Theaflavin-3,3'-Digallate Protects Cartilage from Degradation by Modulating Inflammation and Antioxidant Pathways.
Oxidative medicine and cellular longevity
Teng Y,Jin Z,Ren W,Lu M,Hou M,Zhou Q,Wang W,Yang H,Zou J
Tue Jul 19 00:00:00 UTC 2022
Theaflavin-3,3'-Digallate Protects Cartilage from Degradation by Modulating Inflammation and Antioxidant Pathways.
Oxidative medicine and cellular longevity
Teng Y,Jin Z,Ren W,Lu M,Hou M,Zhou Q,Wang W,Yang H,Zou J
Tue Jul 19 00:00:00 UTC 2022
Carbon dots derived from folic acid attenuates osteoarthritis by protecting chondrocytes through NF-κB/MAPK pathway and reprogramming macrophages.
Journal of nanobiotechnology
Jin Y,Zhang Q,Qin X,Liu Z,Li Z,Zhong X,Xia L,He J,Fang B
Thu Nov 03 00:00:00 UTC 2022
Carbon dots derived from folic acid attenuates osteoarthritis by protecting chondrocytes through NF-κB/MAPK pathway and reprogramming macrophages.
Journal of nanobiotechnology
Jin Y,Zhang Q,Qin X,Liu Z,Li Z,Zhong X,Xia L,He J,Fang B
Thu Nov 03 00:00:00 UTC 2022
Carbon dots derived from folic acid attenuates osteoarthritis by protecting chondrocytes through NF-κB/MAPK pathway and reprogramming macrophages.
Journal of nanobiotechnology
Jin Y,Zhang Q,Qin X,Liu Z,Li Z,Zhong X,Xia L,He J,Fang B
Thu Nov 03 00:00:00 UTC 2022
Exosomes derived from platelet-rich plasma administration in site mediate cartilage protection in subtalar osteoarthritis.
Journal of nanobiotechnology
Zhang Y,Wang X,Chen J,Qian D,Gao P,Qin T,Jiang T,Yi J,Xu T,Huang Y,Wang Q,Zhou Z,Bao T,Zhao X,Liu H,Zheng Z,Fan J,Zhao S,Li Q,Yin G
Sat Jan 29 00:00:00 UTC 2022
Arctiin-reinforced antioxidant microcarrier antagonizes osteoarthritis progression.
Journal of nanobiotechnology
Liu Y,Hou M,Pan Z,Tian X,Zhao Z,Liu T,Yang H,Shi Q,Chen X,Zhang Y,He F,Zhu X
Mon Jun 27 00:00:00 UTC 2022
Arctiin-reinforced antioxidant microcarrier antagonizes osteoarthritis progression.
Journal of nanobiotechnology
Liu Y,Hou M,Pan Z,Tian X,Zhao Z,Liu T,Yang H,Shi Q,Chen X,Zhang Y,He F,Zhu X
Mon Jun 27 00:00:00 UTC 2022
The Protective Effect of Evodiamine in Osteoarthritis: An In Vitro and In Vivo Study in Mice Model.
Frontiers in pharmacology
Xian S,Lin Z,Zhou C,Wu X
Sat Jul 16 00:00:00 UTC 2022
Piceatannol suppresses inflammation and promotes apoptosis in rheumatoid arthritis‑fibroblast‑like synoviocytes by inhibiting the NF‑κB and MAPK signaling pathways.
Molecular medicine reports
Gao X,Kang X,Lu H,Xue E,Chen R,Pan J,Ma J
Sun May 01 00:00:00 UTC 2022
Piceatannol suppresses inflammation and promotes apoptosis in rheumatoid arthritis‑fibroblast‑like synoviocytes by inhibiting the NF‑κB and MAPK signaling pathways.
Molecular medicine reports
Gao X,Kang X,Lu H,Xue E,Chen R,Pan J,Ma J
Sun May 01 00:00:00 UTC 2022
Piceatannol suppresses inflammation and promotes apoptosis in rheumatoid arthritis‑fibroblast‑like synoviocytes by inhibiting the NF‑κB and MAPK signaling pathways.
Molecular medicine reports
Gao X,Kang X,Lu H,Xue E,Chen R,Pan J,Ma J
Sun May 01 00:00:00 UTC 2022
Regulation of osteoarthritis development by ADAM17/Tace in articular cartilage.
Journal of bone and mineral metabolism
Kaneko T,Horiuchi K,Chijimatsu R,Mori D,Nagata K,Omata Y,Yano F,Inui H,Moro T,Tanaka S,Saito T
Tue Mar 01 00:00:00 UTC 2022
Circular RNA circNFKB1 promotes osteoarthritis progression through interacting with ENO1 and sustaining NF-κB signaling.
Cell death & disease
Tang S,Nie X,Ruan J,Cao Y,Kang J,Ding C
Tue Aug 09 00:00:00 UTC 2022
Circular RNA circNFKB1 promotes osteoarthritis progression through interacting with ENO1 and sustaining NF-κB signaling.
Cell death & disease
Tang S,Nie X,Ruan J,Cao Y,Kang J,Ding C
Tue Aug 09 00:00:00 UTC 2022
Silencing of Angiopoietin-Like Protein 4 (Angptl4) Decreases Inflammation, Extracellular Matrix Degradation, and Apoptosis in Osteoarthritis via the Sirtuin 1/NF-κB Pathway.
Oxidative medicine and cellular longevity
Jia C,Li X,Pan J,Ma H,Wu D,Lu H,Wang W,Zhang X,Yi X
Fri Sep 09 00:00:00 UTC 2022
Silencing of Angiopoietin-Like Protein 4 (Angptl4) Decreases Inflammation, Extracellular Matrix Degradation, and Apoptosis in Osteoarthritis via the Sirtuin 1/NF-κB Pathway.
Oxidative medicine and cellular longevity
Jia C,Li X,Pan J,Ma H,Wu D,Lu H,Wang W,Zhang X,Yi X
Fri Sep 09 00:00:00 UTC 2022
Silencing of Angiopoietin-Like Protein 4 (Angptl4) Decreases Inflammation, Extracellular Matrix Degradation, and Apoptosis in Osteoarthritis via the Sirtuin 1/NF-κB Pathway.
Oxidative medicine and cellular longevity
Jia C,Li X,Pan J,Ma H,Wu D,Lu H,Wang W,Zhang X,Yi X
Fri Sep 09 00:00:00 UTC 2022
The lncRNA PILA promotes NF-κB signaling in osteoarthritis by stimulating the activity of the protein arginine methyltransferase PRMT1.
Science signaling
Tang S,Cao Y,Cai Z,Nie X,Ruan J,Zhou Z,Ruan G,Zhu Z,Han W,Ding C
Tue May 24 00:00:00 UTC 2022
The lncRNA PILA promotes NF-κB signaling in osteoarthritis by stimulating the activity of the protein arginine methyltransferase PRMT1.
Science signaling
Tang S,Cao Y,Cai Z,Nie X,Ruan J,Zhou Z,Ruan G,Zhu Z,Han W,Ding C
Tue May 24 00:00:00 UTC 2022
The lncRNA PILA promotes NF-κB signaling in osteoarthritis by stimulating the activity of the protein arginine methyltransferase PRMT1.
Science signaling
Tang S,Cao Y,Cai Z,Nie X,Ruan J,Zhou Z,Ruan G,Zhu Z,Han W,Ding C
Tue May 24 00:00:00 UTC 2022
The lncRNA PILA promotes NF-κB signaling in osteoarthritis by stimulating the activity of the protein arginine methyltransferase PRMT1.
Science signaling
Tang S,Cao Y,Cai Z,Nie X,Ruan J,Zhou Z,Ruan G,Zhu Z,Han W,Ding C
Tue May 24 00:00:00 UTC 2022
Transforming growth factor-β receptors mediates matrix degradation and abnormal hypertrophy in T-2 toxin-induced hypertrophic chondrocytes.
Toxicon : official journal of the International Society on Toxinology
Zhang Y,Li Z,He Y,Zhang M,Feng Y,Fang Q,Ma T,Deng X,Chen J
Tue Feb 01 00:00:00 UTC 2022
Protective role of Achyranthes bidentata polysaccharides against chondrocyte extracellular matrix degeneration through lncRNA GAS5 in osteoarthritis.
Experimental and therapeutic medicine
Fu C,Qiu Z,Huang Y,Mei Y,Lin Q,Zeng J,Zhong W,Ma D
Mon Aug 01 00:00:00 UTC 2022
PCB153 suppressed autophagy via PI3K/Akt/mTOR and RICTOR/Akt/mTOR signaling by the upregulation of microRNA-155 in rat primary chondrocytes.
Toxicology and applied pharmacology
Liu Z,Huang Y,Jin X,Liu L,Gu H
Mon Aug 15 00:00:00 UTC 2022
PCB153 suppressed autophagy via PI3K/Akt/mTOR and RICTOR/Akt/mTOR signaling by the upregulation of microRNA-155 in rat primary chondrocytes.
Toxicology and applied pharmacology
Liu Z,Huang Y,Jin X,Liu L,Gu H
Mon Aug 15 00:00:00 UTC 2022
PCB153 suppressed autophagy via PI3K/Akt/mTOR and RICTOR/Akt/mTOR signaling by the upregulation of microRNA-155 in rat primary chondrocytes.
Toxicology and applied pharmacology
Liu Z,Huang Y,Jin X,Liu L,Gu H
Mon Aug 15 00:00:00 UTC 2022
Oxymatrine Protects Chondrocytes against IL-1β-triggered Apoptosis in Vitro and Inhibits Osteoarthritis in Mice Model.
Evidence-based complementary and alternative medicine : eCAM
Mohetaer D,Cao L,Wang Y
Sun Oct 09 00:00:00 UTC 2022
ALPK1 Aggravates TMJOA Cartilage Degradation via NF-κB and ERK1/2 Signaling.
Journal of dental research
Liu X,Zhao J,Jiang H,Li H,Feng Y,Ke J,Long X
Tue Nov 01 00:00:00 UTC 2022
ALPK1 Aggravates TMJOA Cartilage Degradation via NF-κB and ERK1/2 Signaling.
Journal of dental research
Liu X,Zhao J,Jiang H,Li H,Feng Y,Ke J,Long X
Tue Nov 01 00:00:00 UTC 2022
Anti-inflammatory and immunomodulatory effects of the extracellular vesicles derived from human umbilical cord mesenchymal stem cells on osteoarthritis via M2 macrophages.
Journal of nanobiotechnology
Li K,Yan G,Huang H,Zheng M,Ma K,Cui X,Lu D,Zheng L,Zhu B,Cheng J,Zhao J
Thu Jan 20 00:00:00 UTC 2022
Anti-inflammatory and immunomodulatory effects of the extracellular vesicles derived from human umbilical cord mesenchymal stem cells on osteoarthritis via M2 macrophages.
Journal of nanobiotechnology
Li K,Yan G,Huang H,Zheng M,Ma K,Cui X,Lu D,Zheng L,Zhu B,Cheng J,Zhao J
Thu Jan 20 00:00:00 UTC 2022
Anti-inflammatory and immunomodulatory effects of the extracellular vesicles derived from human umbilical cord mesenchymal stem cells on osteoarthritis via M2 macrophages.
Journal of nanobiotechnology
Li K,Yan G,Huang H,Zheng M,Ma K,Cui X,Lu D,Zheng L,Zhu B,Cheng J,Zhao J
Thu Jan 20 00:00:00 UTC 2022
Anti-inflammatory and immunomodulatory effects of the extracellular vesicles derived from human umbilical cord mesenchymal stem cells on osteoarthritis via M2 macrophages.
Journal of nanobiotechnology
Li K,Yan G,Huang H,Zheng M,Ma K,Cui X,Lu D,Zheng L,Zhu B,Cheng J,Zhao J
Thu Jan 20 00:00:00 UTC 2022
Histone demethylase JMJD3 downregulation protects against aberrant force-induced osteoarthritis through epigenetic control of NR4A1.
International journal of oral science
Jin Y,Liu Z,Li Z,Li H,Zhu C,Li R,Zhou T,Fang B
Thu Jul 14 00:00:00 UTC 2022
Histone demethylase JMJD3 downregulation protects against aberrant force-induced osteoarthritis through epigenetic control of NR4A1.
International journal of oral science
Jin Y,Liu Z,Li Z,Li H,Zhu C,Li R,Zhou T,Fang B
Thu Jul 14 00:00:00 UTC 2022
Histone demethylase JMJD3 downregulation protects against aberrant force-induced osteoarthritis through epigenetic control of NR4A1.
International journal of oral science
Jin Y,Liu Z,Li Z,Li H,Zhu C,Li R,Zhou T,Fang B
Thu Jul 14 00:00:00 UTC 2022
TET enzymes regulate skeletal development through increasing chromatin accessibility of RUNX2 target genes.
Nature communications
Wang L,You X,Ruan D,Shao R,Dai HQ,Shen W,Xu GL,Liu W,Zou W
Thu Aug 11 00:00:00 UTC 2022
Stabilization of hypoxia-inducible factor-1α alleviates osteoarthritis via interacting with Per2 and resetting the circadian clock.
Tissue & cell
Wang C,Zhang Y,Wang Z,Yu W,Tong M,Yan Z
Thu Dec 01 00:00:00 UTC 2022
Stabilization of hypoxia-inducible factor-1α alleviates osteoarthritis via interacting with Per2 and resetting the circadian clock.
Tissue & cell
Wang C,Zhang Y,Wang Z,Yu W,Tong M,Yan Z
Thu Dec 01 00:00:00 UTC 2022
Epigallocatechin-3-O-gallate ameliorates oxidative stress-induced chondrocyte dysfunction and exerts chondroprotective effects via the Keap1/Nrf2/ARE signaling pathway.
Chemical biology & drug design
Zhu W,Tang H,Cao L,Zhang J,Li J,Ma D,Guo C
Fri Jul 01 00:00:00 UTC 2022
Deferoxamine Alleviates Osteoarthritis by Inhibiting Chondrocyte Ferroptosis and Activating the Nrf2 Pathway.
Frontiers in pharmacology
Guo Z,Lin J,Sun K,Guo J,Yao X,Wang G,Hou L,Xu J,Guo J,Guo F
Tue May 30 00:00:00 UTC 2023
Deferoxamine Alleviates Osteoarthritis by Inhibiting Chondrocyte Ferroptosis and Activating the Nrf2 Pathway.
Frontiers in pharmacology
Guo Z,Lin J,Sun K,Guo J,Yao X,Wang G,Hou L,Xu J,Guo J,Guo F
Tue May 30 00:00:00 UTC 2023
Fermentation supernatant of Staphylococcus aureus drives catabolism in chondrocytes via NF-κB signaling mediated increase of cholesterol metabolism.
Experimental cell research
Wang Q,Huang J,Li S,Zhang Y,Sun R,Ren J,Shi S,Cui L
Sat Jan 01 00:00:00 UTC 2022
Natural product, bilobalide, improves joint health in rabbits with osteoarthritis by anti-matrix degradation and antioxidant activities.
Frontiers in veterinary science
Ma T,Chen H,Ruan H,Lv L,Yu Y,Jia L,Zhao J,Li X,Zang Y,Xu X,Zhang J,Gao L
Tue Nov 08 00:00:00 UTC 2022
Natural product, bilobalide, improves joint health in rabbits with osteoarthritis by anti-matrix degradation and antioxidant activities.
Frontiers in veterinary science
Ma T,Chen H,Ruan H,Lv L,Yu Y,Jia L,Zhao J,Li X,Zang Y,Xu X,Zhang J,Gao L
Tue Nov 08 00:00:00 UTC 2022
FABP4 secreted by M1-polarized macrophages promotes synovitis and angiogenesis to exacerbate rheumatoid arthritis.
Bone research
Guo D,Lin C,Lu Y,Guan H,Qi W,Zhang H,Shao Y,Zeng C,Zhang R,Zhang H,Bai X,Cai D
Wed Jun 22 00:00:00 UTC 2022
Cepharanthine Ameliorates Chondrocytic Inflammation and Osteoarthritis via Regulating the MAPK/NF-κB-Autophagy Pathway.
Frontiers in pharmacology
Yao M,Zhang C,Ni L,Ji X,Hong J,Chen Y,Wang J,Li C,Lin J,Lu T,Sheng Y,Sun M,Shi M,Zhou C,Cai X
Sat Jul 16 00:00:00 UTC 2022
Cepharanthine Ameliorates Chondrocytic Inflammation and Osteoarthritis via Regulating the MAPK/NF-κB-Autophagy Pathway.
Frontiers in pharmacology
Yao M,Zhang C,Ni L,Ji X,Hong J,Chen Y,Wang J,Li C,Lin J,Lu T,Sheng Y,Sun M,Shi M,Zhou C,Cai X
Sat Jul 16 00:00:00 UTC 2022
Chicoric acid attenuates tumor necrosis factor-α-induced inflammation and apoptosis via the Nrf2/HO-1, PI3K/AKT and NF-κB signaling pathways in C28/I2 cells and ameliorates the progression of osteoarthritis in a rat model.
International immunopharmacology
Qu Y,Shen Y,Teng L,Huang Y,Yang Y,Jian X,Fan S,Wu P,Fu Q
Sat Oct 01 00:00:00 UTC 2022
Chicoric acid attenuates tumor necrosis factor-α-induced inflammation and apoptosis via the Nrf2/HO-1, PI3K/AKT and NF-κB signaling pathways in C28/I2 cells and ameliorates the progression of osteoarthritis in a rat model.
International immunopharmacology
Qu Y,Shen Y,Teng L,Huang Y,Yang Y,Jian X,Fan S,Wu P,Fu Q
Sat Oct 01 00:00:00 UTC 2022
Enhancing autophagy and energy metabolism in the meniscus can delay the occurrence of PTOA in ACLT rat.
Frontiers in cell and developmental biology
Zhu H,Liu H,Chen X,Xu X,Zhang S,Xie D
Tue Sep 20 00:00:00 UTC 2022
Enhancing autophagy and energy metabolism in the meniscus can delay the occurrence of PTOA in ACLT rat.
Frontiers in cell and developmental biology
Zhu H,Liu H,Chen X,Xu X,Zhang S,Xie D
Tue Sep 20 00:00:00 UTC 2022
Hyaluronic acid ameliorates intervertebral disc degeneration via promoting mitophagy activation.
Frontiers in bioengineering and biotechnology
Zhang F,Wang S,Gao M,Li B,He Z,Tang T,Zhu Z,Liu S,Zhou Z
Tue Jan 03 00:00:00 UTC 2023
Hyaluronic acid ameliorates intervertebral disc degeneration via promoting mitophagy activation.
Frontiers in bioengineering and biotechnology
Zhang F,Wang S,Gao M,Li B,He Z,Tang T,Zhu Z,Liu S,Zhou Z
Tue Jan 03 00:00:00 UTC 2023
Hyaluronic acid ameliorates intervertebral disc degeneration via promoting mitophagy activation.
Frontiers in bioengineering and biotechnology
Zhang F,Wang S,Gao M,Li B,He Z,Tang T,Zhu Z,Liu S,Zhou Z
Tue Jan 03 00:00:00 UTC 2023
Hyaluronic acid ameliorates intervertebral disc degeneration via promoting mitophagy activation.
Frontiers in bioengineering and biotechnology
Zhang F,Wang S,Gao M,Li B,He Z,Tang T,Zhu Z,Liu S,Zhou Z
Tue Jan 03 00:00:00 UTC 2023
Selenium-sensitive histone deacetylase 2 is required for forkhead box O3A and regulates extracellular matrix metabolism in cartilage.
Journal of bone and mineral metabolism
Zhao Y,Guo Y,Sun M,Hussion S,Zheng Y,Huang H,Huo X,Zhao Y,Zhang F,Han Y,Ning Q,Xu P,Sun J,Lu S
Tue Nov 01 00:00:00 UTC 2022
Omentin-1 promoted proliferation and ameliorated inflammation, apoptosis, and degeneration in human nucleus pulposus cells.
Archives of gerontology and geriatrics
Cabral VLF,Wang F,Peng X,Gao J,Zhou Z,Sun R,Bao J,Wu X
Tue Jul 12 00:00:00 UTC 2022
Omentin-1 promoted proliferation and ameliorated inflammation, apoptosis, and degeneration in human nucleus pulposus cells.
Archives of gerontology and geriatrics
Cabral VLF,Wang F,Peng X,Gao J,Zhou Z,Sun R,Bao J,Wu X
Tue Jul 12 00:00:00 UTC 2022
Mesenchymal stromal cell-derived septoclasts resorb cartilage during developmental ossification and fracture healing.
Nature communications
Sivaraj KK,Majev PG,Jeong HW,Dharmalingam B,Zeuschner D,Schröder S,Bixel MG,Timmen M,Stange R,Adams RH
Fri Jan 28 00:00:00 UTC 2022
Runx2 and Runx3 differentially regulate articular chondrocytes during surgically induced osteoarthritis development.
Nature communications
Nagata K,Hojo H,Chang SH,Okada H,Yano F,Chijimatsu R,Omata Y,Mori D,Makii Y,Kawata M,Kaneko T,Iwanaga Y,Nakamoto H,Maenohara Y,Tachibana N,Ishikura H,Higuchi J,Taniguchi Y,Ohba S,Chung UI,Tanaka S,Saito T
Wed Oct 19 00:00:00 UTC 2022
TGF-β1 regulates chondrocyte proliferation and extracellular matrix synthesis via circPhf21a-Vegfa axis in osteoarthritis.
Cell communication and signaling : CCS
Lin S,Li H,Wu B,Shang J,Jiang N,Peng R,Xing B,Xu X,Lu H
Mon May 30 00:00:00 UTC 2022
TGF-β1 regulates chondrocyte proliferation and extracellular matrix synthesis via circPhf21a-Vegfa axis in osteoarthritis.
Cell communication and signaling : CCS
Lin S,Li H,Wu B,Shang J,Jiang N,Peng R,Xing B,Xu X,Lu H
Mon May 30 00:00:00 UTC 2022
ALPK1 Accelerates the Pathogenesis of Osteoarthritis by Activating NLRP3 Signaling.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
Liu X,Zhao J,Jiang H,Guo H,Li Y,Li H,Feng Y,Ke J,Long X
Sat Oct 01 00:00:00 UTC 2022
A plant-derived natural photosynthetic system for improving cell anabolism.
Nature
Chen P,Liu X,Gu C,Zhong P,Song N,Li M,Dai Z,Fang X,Liu Z,Zhang J,Tang R,Fan S,Lin X
Thu Dec 01 00:00:00 UTC 2022
Omaveloxolone inhibits IL-1β-induced chondrocyte apoptosis through the Nrf2/ARE and NF-κB signalling pathways in vitro and attenuates osteoarthritis in vivo.
Frontiers in pharmacology
Jiang Z,Qi G,Lu W,Wang H,Li D,Chen W,Ding L,Yang X,Yuan H,Zeng Q
Sat Oct 15 00:00:00 UTC 2022
Omaveloxolone inhibits IL-1β-induced chondrocyte apoptosis through the Nrf2/ARE and NF-κB signalling pathways in vitro and attenuates osteoarthritis in vivo.
Frontiers in pharmacology
Jiang Z,Qi G,Lu W,Wang H,Li D,Chen W,Ding L,Yang X,Yuan H,Zeng Q
Sat Oct 15 00:00:00 UTC 2022
Iron overload promotes intervertebral disc degeneration via inducing oxidative stress and ferroptosis in endplate chondrocytes.
Free radical biology & medicine
Wang W,Jing X,Du T,Ren J,Liu X,Chen F,Shao Y,Sun S,Yang G,Cui X
Thu Sep 01 00:00:00 UTC 2022
Iron overload promotes intervertebral disc degeneration via inducing oxidative stress and ferroptosis in endplate chondrocytes.
Free radical biology & medicine
Wang W,Jing X,Du T,Ren J,Liu X,Chen F,Shao Y,Sun S,Yang G,Cui X
Thu Sep 01 00:00:00 UTC 2022
Oroxin B alleviates osteoarthritis through anti-inflammation and inhibition of PI3K/AKT/mTOR signaling pathway and enhancement of autophagy.
Frontiers in endocrinology
Lu R,He Z,Zhang W,Wang Y,Cheng P,Lv Z,Yuan X,Guo F,You H,Chen AM,Hu W
Tue Dec 20 00:00:00 UTC 2022
Oroxin B alleviates osteoarthritis through anti-inflammation and inhibition of PI3K/AKT/mTOR signaling pathway and enhancement of autophagy.
Frontiers in endocrinology
Lu R,He Z,Zhang W,Wang Y,Cheng P,Lv Z,Yuan X,Guo F,You H,Chen AM,Hu W
Tue Dec 20 00:00:00 UTC 2022
Oroxin B alleviates osteoarthritis through anti-inflammation and inhibition of PI3K/AKT/mTOR signaling pathway and enhancement of autophagy.
Frontiers in endocrinology
Lu R,He Z,Zhang W,Wang Y,Cheng P,Lv Z,Yuan X,Guo F,You H,Chen AM,Hu W
Tue Dec 20 00:00:00 UTC 2022
XMU-MP-1 attenuates osteoarthritis via inhibiting cartilage degradation and chondrocyte apoptosis.
Frontiers in bioengineering and biotechnology
Hao X,Zhao J,Jia L,He T,Wang H,Fan J,Yang Y,Su F,Lu Q,Zheng C,Yang L,Jie Q
Fri Oct 07 00:00:00 UTC 2022
Selenium Attenuates TBHP-Induced Apoptosis of Nucleus Pulposus Cells by Suppressing Mitochondrial Fission through Activating Nuclear Factor Erythroid 2-Related Factor 2.
Oxidative medicine and cellular longevity
Wang P,Zhang S,Liu W,Chen S,Lv X,Hu B,Shao Z
Mon Apr 25 00:00:00 UTC 2022
S100A10 regulates tumor necrosis factor alpha-induced apoptosis in chondrocytes via the reactive oxygen species/nuclear factor-kappa B pathway.
Biotechnology and applied biochemistry
Guo Y,Li R,Dang X
Thu Dec 01 00:00:00 UTC 2022
Oxidative stress-induced circKIF18A downregulation impairs MCM7-mediated anti-senescence in intervertebral disc degeneration.
Experimental & molecular medicine
Wang J,Xia D,Lin Y,Xu W,Wu Y,Chen J,Chu J,Shen P,Weng S,Wang X,Shen L,Fan S,Shen S
Tue Mar 01 00:00:00 UTC 2022
Oxidative stress-induced circKIF18A downregulation impairs MCM7-mediated anti-senescence in intervertebral disc degeneration.
Experimental & molecular medicine
Wang J,Xia D,Lin Y,Xu W,Wu Y,Chen J,Chu J,Shen P,Weng S,Wang X,Shen L,Fan S,Shen S
Tue Mar 01 00:00:00 UTC 2022
Oxidative stress-induced circKIF18A downregulation impairs MCM7-mediated anti-senescence in intervertebral disc degeneration.
Experimental & molecular medicine
Wang J,Xia D,Lin Y,Xu W,Wu Y,Chen J,Chu J,Shen P,Weng S,Wang X,Shen L,Fan S,Shen S
Tue Mar 01 00:00:00 UTC 2022
Oxidative stress-induced circKIF18A downregulation impairs MCM7-mediated anti-senescence in intervertebral disc degeneration.
Experimental & molecular medicine
Wang J,Xia D,Lin Y,Xu W,Wu Y,Chen J,Chu J,Shen P,Weng S,Wang X,Shen L,Fan S,Shen S
Tue Mar 01 00:00:00 UTC 2022
Dual-dynamic-bond cross-linked injectable hydrogel of multifunction for intervertebral disc degeneration therapy.
Journal of nanobiotechnology
Yang L,Yu C,Fan X,Zeng T,Yang W,Xia J,Wang J,Yao L,Hu C,Jin Y,Zhu Y,Chen J,Hu Z
Sat Oct 01 00:00:00 UTC 2022
Dual-dynamic-bond cross-linked injectable hydrogel of multifunction for intervertebral disc degeneration therapy.
Journal of nanobiotechnology
Yang L,Yu C,Fan X,Zeng T,Yang W,Xia J,Wang J,Yao L,Hu C,Jin Y,Zhu Y,Chen J,Hu Z
Sat Oct 01 00:00:00 UTC 2022
Cartilage Repair Using Clematis Triterpenoid Saponin Delivery Microcarrier, Cultured in a Microgravity Bioreactor Prior to Application in Rabbit Model.
ACS biomaterials science & engineering
Tu P,Pan Y,Wu C,Yang G,Zhou X,Sun J,Wang L,Liu M,Wang Z,Liang Z,Guo Y,Ma Y
Mon Feb 14 00:00:00 UTC 2022
3,3'-diindolylmethane inhibits LPS-induced human chondrocytes apoptosis and extracellular matrix degradation by activating PI3K-Akt-mTOR-mediated autophagy.
Frontiers in pharmacology
Tang H,Qin K,Wang A,Li S,Fang S,Gao W,Lu M,Huang W,Zhang H,Yin Z
Tue Nov 29 00:00:00 UTC 2022
3,3'-diindolylmethane inhibits LPS-induced human chondrocytes apoptosis and extracellular matrix degradation by activating PI3K-Akt-mTOR-mediated autophagy.
Frontiers in pharmacology
Tang H,Qin K,Wang A,Li S,Fang S,Gao W,Lu M,Huang W,Zhang H,Yin Z
Tue Nov 29 00:00:00 UTC 2022
3,3'-diindolylmethane inhibits LPS-induced human chondrocytes apoptosis and extracellular matrix degradation by activating PI3K-Akt-mTOR-mediated autophagy.
Frontiers in pharmacology
Tang H,Qin K,Wang A,Li S,Fang S,Gao W,Lu M,Huang W,Zhang H,Yin Z
Tue Nov 29 00:00:00 UTC 2022
Calycosin mitigates chondrocyte inflammation and apoptosis by inhibiting the PI3K/AKT and NF-κB pathways.
Journal of ethnopharmacology
Shi X,Jie L,Wu P,Zhang N,Mao J,Wang P,Yin S
Fri Oct 28 00:00:00 UTC 2022
Mettl3 inhibits the apoptosis and autophagy of chondrocytes in inflammation through mediating Bcl2 stability via Ythdf1-mediated m6A modification.
Bone
He Y,Wang W,Xu X,Yang B,Yu X,Wu Y,Wang J
Sat Jan 01 00:00:00 UTC 2022
Flavokawain A alleviates the progression of mouse osteoarthritis: An in vitro and in vivo study.
Frontiers in bioengineering and biotechnology
Jing S,Wan J,Wang T,He Z,Ding Q,Sheng G,Wang S,Zhao H,Zhu Z,Wu H,Li W
Fri Dec 23 00:00:00 UTC 2022
Flavokawain A alleviates the progression of mouse osteoarthritis: An in vitro and in vivo study.
Frontiers in bioengineering and biotechnology
Jing S,Wan J,Wang T,He Z,Ding Q,Sheng G,Wang S,Zhao H,Zhu Z,Wu H,Li W
Fri Dec 23 00:00:00 UTC 2022
Cyclic Polypeptide D7 Protects Bone Marrow Mesenchymal Cells and Promotes Chondrogenesis during Osteonecrosis of the Femoral Head via Growth Differentiation Factor 15-Mediated Redox Signaling.
Oxidative medicine and cellular longevity
Chen J,Cui Z,Wang Y,Lyu L,Feng C,Feng D,Cheng Y,Li Z,Sun S
Thu Mar 24 00:00:00 UTC 2022
Self-amplifying loop of NF-κB and periostin initiated by PIEZO1 accelerates mechano-induced senescence of nucleus pulposus cells and intervertebral disc degeneration.
Molecular therapy : the journal of the American Society of Gene Therapy
Wu J,Chen Y,Liao Z,Liu H,Zhang S,Zhong D,Qiu X,Chen T,Su D,Ke X,Wan Y,Zhou T,Su P
Wed Oct 05 00:00:00 UTC 2022
Itaconate attenuates osteoarthritis by inhibiting STING/NF-κB axis in chondrocytes and promoting M2 polarization in macrophages.
Biochemical pharmacology
Ni L,Lin Z,Hu S,Shi Y,Jiang Z,Zhao J,Zhou Y,Wu Y,Tian N,Sun L,Wu A,Pan Z,Zhang X,Wang X
Fri Apr 01 00:00:00 UTC 2022
Itaconate attenuates osteoarthritis by inhibiting STING/NF-κB axis in chondrocytes and promoting M2 polarization in macrophages.
Biochemical pharmacology
Ni L,Lin Z,Hu S,Shi Y,Jiang Z,Zhao J,Zhou Y,Wu Y,Tian N,Sun L,Wu A,Pan Z,Zhang X,Wang X
Fri Apr 01 00:00:00 UTC 2022
Itaconate attenuates osteoarthritis by inhibiting STING/NF-κB axis in chondrocytes and promoting M2 polarization in macrophages.
Biochemical pharmacology
Ni L,Lin Z,Hu S,Shi Y,Jiang Z,Zhao J,Zhou Y,Wu Y,Tian N,Sun L,Wu A,Pan Z,Zhang X,Wang X
Fri Apr 01 00:00:00 UTC 2022
Vasorin-containing small extracellular vesicles retard intervertebral disc degeneration utilizing an injectable thermoresponsive delivery system.
Journal of nanobiotechnology
Liao Z,Ke W,Liu H,Tong B,Wang K,Feng X,Hua W,Wang B,Song Y,Luo R,Liang H,Zhang W,Zhao K,Li S,Yang C
Mon Sep 19 00:00:00 UTC 2022
Astaxanthin attenuates osteoarthritis progression via inhibiting ferroptosis and regulating mitochondrial function in chondrocytes.
Chemico-biological interactions
Wang X,Liu Z,Peng P,Gong Z,Huang J,Peng H
Sat Oct 01 00:00:00 UTC 2022
HSP70 attenuates compression-induced apoptosis of nucleus pulposus cells by suppressing mitochondrial fission via upregulating the expression of SIRT3.
Experimental & molecular medicine
Hu B,Wang P,Zhang S,Liu W,Lv X,Shi D,Zhao L,Liu H,Wang B,Chen S,Shao Z
Tue Mar 01 00:00:00 UTC 2022
HSP70 attenuates compression-induced apoptosis of nucleus pulposus cells by suppressing mitochondrial fission via upregulating the expression of SIRT3.
Experimental & molecular medicine
Hu B,Wang P,Zhang S,Liu W,Lv X,Shi D,Zhao L,Liu H,Wang B,Chen S,Shao Z
Tue Mar 01 00:00:00 UTC 2022
Shoc2 controls ERK1/2-driven neural crest development by balancing components of the extracellular matrix.
Developmental biology
Norcross RG,Abdelmoti L,Rouchka EC,Andreeva K,Tussey O,Landestoy D,Galperin E
Thu Dec 01 00:00:00 UTC 2022
Use of mesoporous polydopamine nanoparticles as a stable drug-release system alleviates inflammation in knee osteoarthritis.
APL bioengineering
Wang Y,Ge W,Ma Z,Ji G,Wang M,Zhou G,Wang X
Wed Jun 01 00:00:00 UTC 2022
dsRNA Induced IFNβ-MMP13 Axis Drives Corneal Wound Healing.
Investigative ophthalmology & visual science
Lan X,Zhang W,Zhu J,Huang H,Mo K,Guo H,Zhu L,Liu J,Li M,Wang L,Liu C,Ji J,Ouyang H
Tue Feb 01 00:00:00 UTC 2022
dsRNA Induced IFNβ-MMP13 Axis Drives Corneal Wound Healing.
Investigative ophthalmology & visual science
Lan X,Zhang W,Zhu J,Huang H,Mo K,Guo H,Zhu L,Liu J,Li M,Wang L,Liu C,Ji J,Ouyang H
Tue Feb 01 00:00:00 UTC 2022
Osthole Suppresses Knee Osteoarthritis Development by Enhancing Autophagy Activated via the AMPK/ULK1 Pathway.
Molecules (Basel, Switzerland)
Ma T,Wang X,Qu W,Yang L,Jing C,Zhu B,Zhang Y,Xie W
Tue Dec 06 00:00:00 UTC 2022
Osthole Suppresses Knee Osteoarthritis Development by Enhancing Autophagy Activated via the AMPK/ULK1 Pathway.
Molecules (Basel, Switzerland)
Ma T,Wang X,Qu W,Yang L,Jing C,Zhu B,Zhang Y,Xie W
Tue Dec 06 00:00:00 UTC 2022
Nanosilicate-Reinforced Silk Fibroin Hydrogel for Endogenous Regeneration of Both Cartilage and Subchondral Bone.
Advanced healthcare materials
Sheng R,Chen J,Wang H,Luo Y,Liu J,Chen Z,Mo Q,Chi J,Ling C,Tan X,Yao Q,Zhang W
Thu Sep 01 00:00:00 UTC 2022
Magnoflorine attenuates inflammatory responses in RA by regulating the PI3K/Akt/NF-κB and Keap1-Nrf2/HO-1 signalling pathways in vivo and in vitro.
Phytomedicine : international journal of phytotherapy and phytopharmacology
Shen Y,Fan X,Qu Y,Tang M,Huang Y,Peng Y,Fu Q
Thu Sep 01 00:00:00 UTC 2022
Paeoniflorin inhibits pyroptosis of nucleus pulposus cells in an acidic environment and alleviates the degeneration of the intervertebral disc in rats.
Cellular signalling
Dai WY,Luo ZP
Tue Mar 01 00:00:00 UTC 2022
Paeoniflorin inhibits pyroptosis of nucleus pulposus cells in an acidic environment and alleviates the degeneration of the intervertebral disc in rats.
Cellular signalling
Dai WY,Luo ZP
Tue Mar 01 00:00:00 UTC 2022
T-2 toxin induces articular cartilage damage by increasing the expression of MMP-13 via the TGF-β receptor pathway.
Human & experimental toxicology
Zhang Y,Li Z,He Y,Liu Y,Mi G,Chen J
Mon Mar 14 00:00:00 UTC 2022
T-2 toxin induces articular cartilage damage by increasing the expression of MMP-13 via the TGF-β receptor pathway.
Human & experimental toxicology
Zhang Y,Li Z,He Y,Liu Y,Mi G,Chen J
Mon Mar 14 00:00:00 UTC 2022
T-2 toxin induces articular cartilage damage by increasing the expression of MMP-13 via the TGF-β receptor pathway.
Human & experimental toxicology
Zhang Y,Li Z,He Y,Liu Y,Mi G,Chen J
Mon Mar 14 00:00:00 UTC 2022
T-2 toxin induces articular cartilage damage by increasing the expression of MMP-13 via the TGF-β receptor pathway.
Human & experimental toxicology
Zhang Y,Li Z,He Y,Liu Y,Mi G,Chen J
Mon Mar 14 00:00:00 UTC 2022
Corosolic Acid Protects Rat Chondrocytes Against IL-1β-Induced ECM Degradation by Activating Autophagy via PI3K/AKT/mTOR Pathway and Ameliorates Rat Osteoarthritis.
Drug design, development and therapy
Han H,Chen M,Li Z,Zhou S,Wu Y,Wei J
Tue Aug 16 00:00:00 UTC 2022
Corosolic Acid Protects Rat Chondrocytes Against IL-1β-Induced ECM Degradation by Activating Autophagy via PI3K/AKT/mTOR Pathway and Ameliorates Rat Osteoarthritis.
Drug design, development and therapy
Han H,Chen M,Li Z,Zhou S,Wu Y,Wei J
Tue Aug 16 00:00:00 UTC 2022
Corosolic Acid Protects Rat Chondrocytes Against IL-1β-Induced ECM Degradation by Activating Autophagy via PI3K/AKT/mTOR Pathway and Ameliorates Rat Osteoarthritis.
Drug design, development and therapy
Han H,Chen M,Li Z,Zhou S,Wu Y,Wei J
Tue Aug 16 00:00:00 UTC 2022
NRF2-directed PRPS1 upregulation to promote the progression and metastasis of melanoma.
Frontiers in immunology
Xiong G,Feng Y,Yi X,Zhang X,Li X,Yang L,Yi Z,Sai B,Yang Z,Zhang Q,Kuang Y,Zhu Y
Mon Oct 10 00:00:00 UTC 2022
Ellagic acid attenuates interleukin-1β-induced oxidative stress and exerts protective effects on chondrocytes through the Kelch-like ECH-associated protein 1 (Keap1)/ Nuclear factor erythroid 2-related factor 2 (Nrf2) pathway.
Bioengineered
Zhu W,Tang H,Li J,Guedes RM,Cao L,Guo C
Fri Apr 01 00:00:00 UTC 2022
Traumatic temporomandibular joint bony ankylosis in growing rats.
BMC oral health
Ma Z,Wang Y,Xue Y,Zhang W,Li D,Li Y,Li G,Zhou H,Hu X,Deng T,Hu K
Fri Dec 09 00:00:00 UTC 2022
Asiaticoside ameliorates osteoarthritis progression through activation of Nrf2/HO-1 and inhibition of the NF-κB pathway.
International immunopharmacology
Luo P,Huang Q,Chen S,Wang Y,Dou H
Fri Jul 01 00:00:00 UTC 2022
Asiaticoside ameliorates osteoarthritis progression through activation of Nrf2/HO-1 and inhibition of the NF-κB pathway.
International immunopharmacology
Luo P,Huang Q,Chen S,Wang Y,Dou H
Fri Jul 01 00:00:00 UTC 2022
Asiaticoside ameliorates osteoarthritis progression through activation of Nrf2/HO-1 and inhibition of the NF-κB pathway.
International immunopharmacology
Luo P,Huang Q,Chen S,Wang Y,Dou H
Fri Jul 01 00:00:00 UTC 2022
Exosomes derived from hypoxia preconditioned mesenchymal stem cells laden in a silk hydrogel promote cartilage regeneration via the miR-205-5p/PTEN/AKT pathway.
Acta biomaterialia
Shen K,Duan A,Cheng J,Yuan T,Zhou J,Song H,Chen Z,Wan B,Liu J,Zhang X,Zhang Y,Xie R,Liu F,Fan W,Zuo Q
Fri Apr 15 00:00:00 UTC 2022
Intra-articular injection of a novel Wnt pathway inhibitor, SM04690, upregulates Wnt16 expression and reduces disease progression in temporomandibular joint osteoarthritis.
Bone
Hua B,Qiu J,Ye X,Liu X
Sun May 01 00:00:00 UTC 2022
Upregulation of P2Y12 inhibits chondrocyte apoptosis in lumbar osteoarthritis through the PI3K/AKT signaling pathway.
Molecular biology reports
Wu G,Xue P,Jin H,Zhang M,Gui C,Bao G,Xu G,Jiang J,Zhang J,Cui S,Cui Z,Sun Y
Fri Jul 01 00:00:00 UTC 2022
Upregulation of P2Y12 inhibits chondrocyte apoptosis in lumbar osteoarthritis through the PI3K/AKT signaling pathway.
Molecular biology reports
Wu G,Xue P,Jin H,Zhang M,Gui C,Bao G,Xu G,Jiang J,Zhang J,Cui S,Cui Z,Sun Y
Fri Jul 01 00:00:00 UTC 2022
Upregulation of P2Y12 inhibits chondrocyte apoptosis in lumbar osteoarthritis through the PI3K/AKT signaling pathway.
Molecular biology reports
Wu G,Xue P,Jin H,Zhang M,Gui C,Bao G,Xu G,Jiang J,Zhang J,Cui S,Cui Z,Sun Y
Fri Jul 01 00:00:00 UTC 2022
Upregulation of P2Y12 inhibits chondrocyte apoptosis in lumbar osteoarthritis through the PI3K/AKT signaling pathway.
Molecular biology reports
Wu G,Xue P,Jin H,Zhang M,Gui C,Bao G,Xu G,Jiang J,Zhang J,Cui S,Cui Z,Sun Y
Fri Jul 01 00:00:00 UTC 2022
Exosomes-derived miR-125-5p from cartilage endplate stem cells regulates autophagy and ECM metabolism in nucleus pulposus by targeting SUV38H1.
Experimental cell research
Chen D,Jiang X
Sun May 01 00:00:00 UTC 2022
Restoring the dampened expression of the core clock molecule BMAL1 protects against compression-induced intervertebral disc degeneration.
Bone research
Wang D,Peng P,Dudek M,Hu X,Xu X,Shang Q,Wang D,Jia H,Wang H,Gao B,Zheng C,Mao J,Gao C,He X,Cheng P,Wang H,Zheng J,Hoyland JA,Meng QJ,Luo Z,Yang L
Fri Feb 25 00:00:00 UTC 2022
An Injectable Hydrogel Scaffold Loaded with Dual-Drug/Sustained-Release PLGA Microspheres for the Regulation of Macrophage Polarization in the Treatment of Intervertebral Disc Degeneration.
International journal of molecular sciences
Cheng H,Guo Q,Zhao H,Liu K,Kang H,Gao F,Guo J,Yuan X,Hu S,Li F,Yang Q,Fang Z
Mon Dec 26 00:00:00 UTC 2022
An Injectable Hydrogel Scaffold Loaded with Dual-Drug/Sustained-Release PLGA Microspheres for the Regulation of Macrophage Polarization in the Treatment of Intervertebral Disc Degeneration.
International journal of molecular sciences
Cheng H,Guo Q,Zhao H,Liu K,Kang H,Gao F,Guo J,Yuan X,Hu S,Li F,Yang Q,Fang Z
Mon Dec 26 00:00:00 UTC 2022
An Injectable Hydrogel Scaffold Loaded with Dual-Drug/Sustained-Release PLGA Microspheres for the Regulation of Macrophage Polarization in the Treatment of Intervertebral Disc Degeneration.
International journal of molecular sciences
Cheng H,Guo Q,Zhao H,Liu K,Kang H,Gao F,Guo J,Yuan X,Hu S,Li F,Yang Q,Fang Z
Mon Dec 26 00:00:00 UTC 2022
An Injectable Hydrogel Scaffold Loaded with Dual-Drug/Sustained-Release PLGA Microspheres for the Regulation of Macrophage Polarization in the Treatment of Intervertebral Disc Degeneration.
International journal of molecular sciences
Cheng H,Guo Q,Zhao H,Liu K,Kang H,Gao F,Guo J,Yuan X,Hu S,Li F,Yang Q,Fang Z
Mon Dec 26 00:00:00 UTC 2022
Tri-n-butyl phosphate delays tissue repair by dysregulating neutrophil function in zebrafish.
Toxicology and applied pharmacology
Wang Y,Cheng Z,Zhang H,Li S,Pan Y,Zhang W,Huang S,He X,Zou F,Yuan Z,Yan W,Huang H
Mon Aug 15 00:00:00 UTC 2022
Asporin regulated by miR-26b-5p mediates chondrocyte senescence and exacerbates osteoarthritis progression via TGF-β1/Smad2 pathway.
Rheumatology (Oxford, England)
Liu L,Zhao C,Zhang H,Lu Y,Luo B,Yao Z,Shao Y,Zeng H,Zeng C,Zhang R,Fang H,Pan J,Bai X,Cai D
Mon May 30 00:00:00 UTC 2022
Extracellular vesicles derived from human umbilical cord mesenchymal stem cells alleviate osteoarthritis of the knee in mice model by interacting with METTL3 to reduce m6A of NLRP3 in macrophage.
Stem cell research & therapy
Zhou H,Shen X,Yan C,Xiong W,Ma Z,Tan Z,Wang J,Li Y,Liu J,Duan A,Liu F
Sat Jul 16 00:00:00 UTC 2022
Extracellular vesicles derived from human umbilical cord mesenchymal stem cells alleviate osteoarthritis of the knee in mice model by interacting with METTL3 to reduce m6A of NLRP3 in macrophage.
Stem cell research & therapy
Zhou H,Shen X,Yan C,Xiong W,Ma Z,Tan Z,Wang J,Li Y,Liu J,Duan A,Liu F
Sat Jul 16 00:00:00 UTC 2022
LncRNA TM1-3P Regulates Proliferation, Apoptosis and Inflammation of Fibroblasts in Osteoarthritis through miR-144-3p/ONECUT2 Axis.
Orthopaedic surgery
Yi Y,Yang N,Yang Z,Tao X,Li Y
Tue Nov 01 00:00:00 UTC 2022
LncRNA TM1-3P Regulates Proliferation, Apoptosis and Inflammation of Fibroblasts in Osteoarthritis through miR-144-3p/ONECUT2 Axis.
Orthopaedic surgery
Yi Y,Yang N,Yang Z,Tao X,Li Y
Tue Nov 01 00:00:00 UTC 2022
LncRNA TM1-3P Regulates Proliferation, Apoptosis and Inflammation of Fibroblasts in Osteoarthritis through miR-144-3p/ONECUT2 Axis.
Orthopaedic surgery
Yi Y,Yang N,Yang Z,Tao X,Li Y
Tue Nov 01 00:00:00 UTC 2022
LncRNA TM1-3P Regulates Proliferation, Apoptosis and Inflammation of Fibroblasts in Osteoarthritis through miR-144-3p/ONECUT2 Axis.
Orthopaedic surgery
Yi Y,Yang N,Yang Z,Tao X,Li Y
Tue Nov 01 00:00:00 UTC 2022
Metformin mitigates cholesterol accumulation via the AMPK/SIRT1 pathway to protect osteoarthritis chondrocytes.
Biochemical and biophysical research communications
Xing H,Liang C,Wang C,Xu X,Hu Y,Qiu B
Sat Dec 03 00:00:00 UTC 2022
Osteocyte Apoptosis Contributes to Cold Exposure-induced Bone Loss.
Frontiers in bioengineering and biotechnology
Du J,He Z,Cui J,Li H,Xu M,Zhang S,Zhang S,Yan M,Qu X,Yu Z
Wed Jan 05 00:00:00 UTC 2022
Metabolic reprogramming in chondrocytes to promote mitochondrial respiration reduces downstream features of osteoarthritis.
Scientific reports
Ohashi Y,Takahashi N,Terabe K,Tsuchiya S,Kojima T,Knudson CB,Knudson W,Imagama S
Fri Jul 23 00:00:00 UTC 2021
Exhausting circ_0136474 and Restoring miR-766-3p Attenuate Chondrocyte Oxidative Injury in IL-1β-Induced Osteoarthritis Progression Through Regulating DNMT3A.
Frontiers in genetics
Zhu H,Zhu S,Shang X,Meng X,Jing S,Yu L,Deng Y
Tue Jun 08 00:00:00 UTC 2021
Decreased miR-214-3p activates NF-κB pathway and aggravates osteoarthritis progression.
EBioMedicine
Cao Y,Tang S,Nie X,Zhou Z,Ruan G,Han W,Zhu Z,Ding C
Mon Mar 01 00:00:00 UTC 2021
Single-Cell Profiles of Age-Related Osteoarthritis Uncover Underlying Heterogeneity Associated With Disease Progression.
Frontiers in molecular biosciences
Liu W,Chen Y,Zeng G,Yang S,Yang T,Ma M,Song W
Fri Jan 28 00:00:00 UTC 2022
Reducing Inflammation and Vascular Invasion in Intervertebral Disc Degeneration via Cystathionine-γ-Lyase Inhibitory Effect on E-Selectin.
Frontiers in cell and developmental biology
Xu H,Wei K,Tu J,Chen Y,He Y,Ding Y,Xu H,Bao X,Xie H,Fang H,Wang H
Tue Dec 07 00:00:00 UTC 2021
α-Cyperone (CYP) down-regulates NF-κB and MAPKs signaling, attenuating inflammation and extracellular matrix degradation in chondrocytes, to ameliorate osteoarthritis in mice.
Aging
Zhang H,Li S,Lu J,Jin J,Zhu G,Wang L,Yan Y,He L,Wang B,Wang X,Yu H
Thu Jul 08 00:00:00 UTC 2021
LncRNA Malat-1 From MSCs-Derived Extracellular Vesicles Suppresses Inflammation and Cartilage Degradation in Osteoarthritis.
Frontiers in bioengineering and biotechnology
Pan C,Huang W,Chen Q,Xu J,Yao G,Li B,Wu T,Yin C,Cheng X
Tue Jan 04 00:00:00 UTC 2022
The Role of Panx3 in Age-Associated and Injury-Induced Intervertebral Disc Degeneration.
International journal of molecular sciences
Serjeant M,Moon PM,Quinonez D,Penuela S,Beier F,Séguin CA
Fri Jan 22 00:00:00 UTC 2021
Staphylococcus aureus on the effect of expression of MMPs/TIMPs and uPA system in bovine mammary fibroblasts.
Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi
Miao Z,Ding Y,Bi Y,Chen M,Cao X,Wang F
Tue Jun 01 00:00:00 UTC 2021
Compressive force regulates cementoblast migration via downregulation of autophagy.
Journal of periodontology
Yang Y,Huang Y,Liu H,Zheng Y,Jia L,Li W
Mon Nov 01 00:00:00 UTC 2021
Activation of transient receptor potential vanilloid 4 protects articular cartilage against inflammatory responses via CaMKK/AMPK/NF-κB signaling pathway.
Scientific reports
Hattori K,Takahashi N,Terabe K,Ohashi Y,Kishimoto K,Yokota Y,Suzuki M,Kojima T,Imagama S
Fri Jul 30 00:00:00 UTC 2021
Bardoxolone-Methyl Prevents Oxidative Stress-Mediated Apoptosis and Extracellular Matrix Degradation in vitro and Alleviates Osteoarthritis in vivo.
Drug design, development and therapy
Pang Z,Jiang Z,Zhu R,Song C,Tang H,Cao L,Guo C
Thu Jan 20 00:00:00 UTC 2022
Zonal-Layered Chondrocyte Sheets for Repairment of Full-Thickness Articular Cartilage Defect: A Mini-Pig Model.
Biomedicines
Shen PC,Lu CC,Chou SH,Liu ZM,Su SJ,Tien YC
Tue Nov 30 00:00:00 UTC 2021
Inhibition of HDAC6 by Tubastatin A reduces chondrocyte oxidative stress in chondrocytes and ameliorates mouse osteoarthritis by activating autophagy.
Aging
Shen Z,Ji K,Cai Z,Huang C,He X,Xu H,Chen G
Fri Mar 19 00:00:00 UTC 2021
Therapeutic Effects of Naringin in Rheumatoid Arthritis: Network Pharmacology and Experimental Validation.
Frontiers in pharmacology
Aihaiti Y,Song Cai Y,Tuerhong X,Ni Yang Y,Ma Y,Shi Zheng H,Xu K,Xu P
Tue Jun 01 00:00:00 UTC 2021
Effects of HDAC4 on IL-1β-induced matrix metalloproteinase expression regulated partially through the WNT3A/β-catenin pathway.
Chinese medical journal
Ning Q,Gan YH,Shi RR,Meng JH
Thu Apr 08 00:00:00 UTC 2021
TGF-β/Alk5 signaling prevents osteoarthritis initiation via regulating the senescence of articular cartilage stem cells.
Journal of cellular physiology
Tan Q,Wang Q,Kuang L,Zhang J,Peng X,Liang S,Liu M,Chen H,Chen S,Luo X,Qi H,Li C,Luo F,Huang S,Ni Z,Jin M,Su N,Yang J,Yang P,Chen B,Chen L,Du X,Xie Y,Chen L
Thu Jul 01 00:00:00 UTC 2021
MFG-E8 regulated by miR-99b-5p protects against osteoarthritis by targeting chondrocyte senescence and macrophage reprogramming via the NF-κB pathway.
Cell death & disease
Lu Y,Liu L,Pan J,Luo B,Zeng H,Shao Y,Zhang H,Guan H,Guo D,Zeng C,Zhang R,Bai X,Zhang H,Cai D
Tue May 25 00:00:00 UTC 2021
MFG-E8 regulated by miR-99b-5p protects against osteoarthritis by targeting chondrocyte senescence and macrophage reprogramming via the NF-κB pathway.
Cell death & disease
Lu Y,Liu L,Pan J,Luo B,Zeng H,Shao Y,Zhang H,Guan H,Guo D,Zeng C,Zhang R,Bai X,Zhang H,Cai D
Tue May 25 00:00:00 UTC 2021
MicroRNA-497 Reduction and Increase of Its Family Member MicroRNA-424 Lead to Dysregulation of Multiple Inflammation Related Genes in Synovial Fibroblasts With Rheumatoid Arthritis.
Frontiers in immunology
Wang S,Xu J,Guo Y,Cai Y,Ren X,Zhu W,Geng M,Meng L,Jiang C,Lu S
Mon Jun 28 00:00:00 UTC 2021
Effects of mechanical stress and deficiency of dihydrotestosterone or 17β-estradiol on Temporomandibular Joint Osteoarthritis in mice.
Osteoarthritis and cartilage
Ootake T,Ishii T,Sueishi K,Watanabe A,Ishizuka Y,Amano K,Nagao M,Nishimura K,Nishii Y
Mon Nov 01 00:00:00 UTC 2021
Endoplasmic reticulum stress pathway mediates T-2 toxin-induced chondrocyte apoptosis.
Toxicology
Liu YN,Mu YD,Wang H,Zhang M,Shi YW,Mi G,Peng LX,Chen JH
Wed Dec 01 00:00:00 UTC 2021
LncRNA H19-Derived miR-675-5p Accelerates the Invasion of Extravillous Trophoblast Cells by Inhibiting GATA2 and Subsequently Activating Matrix Metalloproteinases.
International journal of molecular sciences
Ogoyama M,Ohkuchi A,Takahashi H,Zhao D,Matsubara S,Takizawa T
Wed Jan 27 00:00:00 UTC 2021
Oroxylin A attenuates IL-1β-induced inflammatory reaction via inhibiting the activation of the ERK and PI3K/AKT signaling pathways in osteoarthritis chondrocytes.
Experimental and therapeutic medicine
Zhang Y,Weng Q,Chen J,Li M,Han J
Thu Apr 01 00:00:00 UTC 2021
Therapeutic effect of neohesperidin on TNF-α-stimulated human rheumatoid arthritis fibroblast-like synoviocytes.
Chinese journal of natural medicines
Wang XH,Dai C,Wang J,Liu R,Li L,Yin ZS
Fri Oct 01 00:00:00 UTC 2021
Integrative analysis of genome-wide DNA methylation and single-nucleotide polymorphism identified ACSM5 as a suppressor of lumbar ligamentum flavum hypertrophy.
Arthritis research & therapy
Cao Y,Zhan Y,Qiu S,Chen Z,Gong K,Ni S,Duan Y
Thu Sep 30 00:00:00 UTC 2021
SP600125 Restored TNF-α-Induced Impaired Chondrogenesis in Bone Mesenchymal Stem Cells and Its Antiosteoarthritis Effect in Mice.
Stem cells and development
Ding N,Zeng MY,Song WJ,Xiao CX,Li EM,Wei B
Fri Oct 15 00:00:00 UTC 2021
SP600125 Restored TNF-α-Induced Impaired Chondrogenesis in Bone Mesenchymal Stem Cells and Its Antiosteoarthritis Effect in Mice.
Stem cells and development
Ding N,Zeng MY,Song WJ,Xiao CX,Li EM,Wei B
Fri Oct 15 00:00:00 UTC 2021
Role of the hippo signaling pathway in the extracellular matrix degradation of chondrocytes induced by fluoride exposure.
Ecotoxicology and environmental safety
Yu FF,Zuo J,Fu X,Gao MH,Sun L,Yu SY,Li Z,Zhou GY,Ba Y
Wed Dec 01 00:00:00 UTC 2021
AMD3465 (hexahydrobromide) rescues the MG63 osteoblasts against the apoptosis induced by high glucose.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Zhang Z,Wu H,Huang S,Chen L,Chen X,Zhang W,Liao L,Zhang X
Tue Jun 01 00:00:00 UTC 2021
Exosome-Encapsulated microRNA-127-3p Released from Bone Marrow-Derived Mesenchymal Stem Cells Alleviates Osteoarthritis Through Regulating CDH11-Mediated Wnt/β-Catenin Pathway.
Journal of pain research
Dong J,Li L,Fang X,Zang M
Wed Apr 20 00:00:00 UTC 2022
ZIP8 mediates the extracellular matrix degradation of nucleus pulposus cells via NF-κB signaling pathway.
Biochemical and biophysical research communications
Ding W,Ge Y,Sun H,Xu J,Gu H,Bian C,Chen H,Jiang L,Yin X
Fri Apr 23 00:00:00 UTC 2021
Scleraxis expressing scleral cells respond to inflammatory stimulation.
Histochemistry and cell biology
Atta G,Schroedl F,Kaser-Eichberger A,Spitzer G,Traweger A,Heindl LM,Tempfer H
Sun Aug 01 00:00:00 UTC 2021
Involvement of Transient Receptor Potential Vanilloid Channel 2 in the Induction of Lubricin and Suppression of Ectopic Endochondral Ossification in Mouse Articular Cartilage.
Arthritis & rheumatology (Hoboken, N.J.)
Nakamoto H,Katanosaka Y,Chijimatsu R,Mori D,Xuan F,Yano F,Omata Y,Maenohara Y,Murahashi Y,Kawaguchi K,Yamagami R,Inui H,Taketomi S,Taniguchi Y,Kanagawa M,Naruse K,Tanaka S,Saito T
Sun Aug 01 00:00:00 UTC 2021
MicroRNA-4423-3p inhibits proliferation of fibroblast-like synoviocytes by targeting matrix metalloproteinase 13 in rheumatoid arthritis.
Bioengineered
Xu W,Ye L,Wu H
Wed Dec 01 00:00:00 UTC 2021
Physalin A Inhibits MAPK and NF-κB Signal Transduction Through Integrin αVβ3 and Exerts Chondroprotective Effect.
Frontiers in pharmacology
Lu R,Yu X,Liang S,Cheng P,Wang Z,He ZY,Lv ZT,Wan J,Mo H,Zhu WT,Chen AM
Tue Dec 21 00:00:00 UTC 2021
Physalin A Inhibits MAPK and NF-κB Signal Transduction Through Integrin αVβ3 and Exerts Chondroprotective Effect.
Frontiers in pharmacology
Lu R,Yu X,Liang S,Cheng P,Wang Z,He ZY,Lv ZT,Wan J,Mo H,Zhu WT,Chen AM
Tue Dec 21 00:00:00 UTC 2021
Physalin A Inhibits MAPK and NF-κB Signal Transduction Through Integrin αVβ3 and Exerts Chondroprotective Effect.
Frontiers in pharmacology
Lu R,Yu X,Liang S,Cheng P,Wang Z,He ZY,Lv ZT,Wan J,Mo H,Zhu WT,Chen AM
Tue Dec 21 00:00:00 UTC 2021
Senolytic agent Quercetin ameliorates intervertebral disc degeneration via the Nrf2/NF-κB axis.
Osteoarthritis and cartilage
Shao Z,Wang B,Shi Y,Xie C,Huang C,Chen B,Zhang H,Zeng G,Liang H,Wu Y,Zhou Y,Tian N,Wu A,Gao W,Wang X,Zhang X
Mon Mar 01 00:00:00 UTC 2021
MCC950, the NLRP3 Inhibitor, Protects against Cartilage Degradation in a Mouse Model of Osteoarthritis.
Oxidative medicine and cellular longevity
Ni B,Pei W,Qu Y,Zhang R,Chu X,Wang Y,Huang X,You H
Mon Feb 14 00:00:00 UTC 2022
MCC950, the NLRP3 Inhibitor, Protects against Cartilage Degradation in a Mouse Model of Osteoarthritis.
Oxidative medicine and cellular longevity
Ni B,Pei W,Qu Y,Zhang R,Chu X,Wang Y,Huang X,You H
Mon Feb 14 00:00:00 UTC 2022
BMP5 silencing inhibits chondrocyte senescence and apoptosis as well as osteoarthritis progression in mice.
Aging
Shao Y,Zhao C,Pan J,Zeng C,Zhang H,Liu L,Fan K,Liu X,Luo B,Fang H,Bai X,Zhang H,Cai D
Fri Mar 19 00:00:00 UTC 2021
Injectable exosome-functionalized extracellular matrix hydrogel for metabolism balance and pyroptosis regulation in intervertebral disc degeneration.
Journal of nanobiotechnology
Xing H,Zhang Z,Mao Q,Wang C,Zhou Y,Zhou X,Ying L,Xu H,Hu S,Zhang N
Mon Sep 06 00:00:00 UTC 2021
TGF-β1-stimulation of NFATC2 and ATF3 proteins and their interaction for matrix metalloproteinase 13 expression in human breast cancer cells.
International journal of biological macromolecules
Rohini M,Vairamani M,Selvamurugan N
Wed Dec 01 00:00:00 UTC 2021
Isovitexin Depresses Osteoarthritis Progression via the Nrf2/NF-κB Pathway: An in vitro Study.
Journal of inflammation research
Hu X,Li R,Sun M,Kong Y,Zhu H,Wang F,Wan Q
Fri Apr 22 00:00:00 UTC 2022
1,25-Dihydroxyvitamin D Inhibits Osteoarthritis by Modulating Interaction Between Vitamin D Receptor and NLRP3 in Macrophages.
Journal of inflammation research
Duan A,Ma Z,Liu W,Shen K,Zhou H,Wang S,Kong R,Shao Y,Chen Y,Guo W,Liu F
Thu Jun 30 00:00:00 UTC 2022
1,25-Dihydroxyvitamin D Inhibits Osteoarthritis by Modulating Interaction Between Vitamin D Receptor and NLRP3 in Macrophages.
Journal of inflammation research
Duan A,Ma Z,Liu W,Shen K,Zhou H,Wang S,Kong R,Shao Y,Chen Y,Guo W,Liu F
Thu Jun 30 00:00:00 UTC 2022
Silencing BLNK protects against interleukin-1β-induced chondrocyte injury through the NF-κB signaling pathway.
Cytokine
Cheng Y,Li F,Zhang WS,Zou GY,Shen YX
Wed Dec 01 00:00:00 UTC 2021
Frugoside delays osteoarthritis progression via inhibiting miR-155-modulated synovial macrophage M1 polarization.
Rheumatology (Oxford, England)
Wang H,Zhang H,Fan K,Zhang D,Hu A,Zeng X,Liu YL,Tan G,Wang H
Sat Oct 02 00:00:00 UTC 2021
d-Mannose suppresses osteoarthritis development in vivo and delays IL-1β-induced degeneration in vitro by enhancing autophagy activated via the AMPK pathway.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Lin Z,Miao J,Zhang T,He M,Zhou X,Zhang H,Gao Y,Bai L
Mon Mar 01 00:00:00 UTC 2021
Cardamonin protects nucleus pulposus cells against IL-1β-induced inflammation and catabolism via Nrf2/NF-κB axis.
Food & function
Xie C,Ma H,Shi Y,Li J,Wu H,Wang B,Shao Z,Huang C,Chen J,Sun L,Zhou Y,Tian N,Wu Y,Gao W,Wu A,Wang X,Zhang X
Sun Mar 21 00:00:00 UTC 2021
Cardamonin protects nucleus pulposus cells against IL-1β-induced inflammation and catabolism via Nrf2/NF-κB axis.
Food & function
Xie C,Ma H,Shi Y,Li J,Wu H,Wang B,Shao Z,Huang C,Chen J,Sun L,Zhou Y,Tian N,Wu Y,Gao W,Wu A,Wang X,Zhang X
Sun Mar 21 00:00:00 UTC 2021
Cardamonin protects nucleus pulposus cells against IL-1β-induced inflammation and catabolism via Nrf2/NF-κB axis.
Food & function
Xie C,Ma H,Shi Y,Li J,Wu H,Wang B,Shao Z,Huang C,Chen J,Sun L,Zhou Y,Tian N,Wu Y,Gao W,Wu A,Wang X,Zhang X
Sun Mar 21 00:00:00 UTC 2021
Glucagon-like peptide-1 receptor activation maintains extracellular matrix integrity by inhibiting the activity of mitogen-activated protein kinases and activator protein-1.
Free radical biology & medicine
Peng Y,Lin H,Tian S,Liu S,Li J,Lv X,Chen S,Zhao L,Pu F,Chen X,Shu H,Qing X,Shao Z
Wed Dec 01 00:00:00 UTC 2021
Glucagon-like peptide-1 receptor activation maintains extracellular matrix integrity by inhibiting the activity of mitogen-activated protein kinases and activator protein-1.
Free radical biology & medicine
Peng Y,Lin H,Tian S,Liu S,Li J,Lv X,Chen S,Zhao L,Pu F,Chen X,Shu H,Qing X,Shao Z
Wed Dec 01 00:00:00 UTC 2021
Acetabular development and fate of inverted limbus in rabbits: Experimental observation from an animal model.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society
Liu J,Zhou W,Chen Y,Li L
Wed Dec 01 00:00:00 UTC 2021
Acetabular development and fate of inverted limbus in rabbits: Experimental observation from an animal model.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society
Liu J,Zhou W,Chen Y,Li L
Wed Dec 01 00:00:00 UTC 2021
Exosomes Isolated From Bone Marrow Mesenchymal Stem Cells Exert a Protective Effect on Osteoarthritis via lncRNA LYRM4-AS1-GRPR-miR-6515-5p.
Frontiers in cell and developmental biology
Wang X,Li Z,Cui Y,Cui X,Chen C,Wang Z
Sat Apr 23 00:00:00 UTC 2022
Suramin attenuates intervertebral disc degeneration by inhibiting NF-κB signalling pathway.
Bone & joint research
Liu ZM,Lu CC,Shen PC,Chou SH,Shih CL,Chen JC,Tien YC
Sun Aug 01 00:00:00 UTC 2021
METTL3 involves the progression of osteoarthritis probably by affecting ECM degradation and regulating the inflammatory response.
Life sciences
Sang W,Xue S,Jiang Y,Lu H,Zhu L,Wang C,Ma J
Sun Aug 01 00:00:00 UTC 2021
Apigenin Alleviates Intervertebral Disc Degeneration via Restoring Autophagy Flux in Nucleus Pulposus Cells.
Frontiers in cell and developmental biology
Xie C,Shi Y,Chen Z,Zhou X,Luo P,Hong C,Tian N,Wu Y,Zhou Y,Lin Y,Dou H,Wu A,Huang Q,Zhang X,Wang X
Tue Feb 01 00:00:00 UTC 2022
Apigenin Alleviates Intervertebral Disc Degeneration via Restoring Autophagy Flux in Nucleus Pulposus Cells.
Frontiers in cell and developmental biology
Xie C,Shi Y,Chen Z,Zhou X,Luo P,Hong C,Tian N,Wu Y,Zhou Y,Lin Y,Dou H,Wu A,Huang Q,Zhang X,Wang X
Tue Feb 01 00:00:00 UTC 2022
Leptin Induced TLR4 Expression via the JAK2-STAT3 Pathway in Obesity-Related Osteoarthritis.
Oxidative medicine and cellular longevity
Jiang M,He J,Sun Y,Dong X,Yao J,Gu H,Liu L
Mon Sep 13 00:00:00 UTC 2021
Aberrant Fluid Shear Stress Contributes to Articular Cartilage Pathogenesis via Epigenetic Regulation of ZBTB20 by H3K4me3.
Journal of inflammation research
Jin Y,Li Z,Wu Y,Li H,Liu Z,Liu L,Ouyang N,Zhou T,Fang B,Xia L
Thu Apr 28 00:00:00 UTC 2022
Aberrant Fluid Shear Stress Contributes to Articular Cartilage Pathogenesis via Epigenetic Regulation of ZBTB20 by H3K4me3.
Journal of inflammation research
Jin Y,Li Z,Wu Y,Li H,Liu Z,Liu L,Ouyang N,Zhou T,Fang B,Xia L
Thu Apr 28 00:00:00 UTC 2022
Aberrant Fluid Shear Stress Contributes to Articular Cartilage Pathogenesis via Epigenetic Regulation of ZBTB20 by H3K4me3.
Journal of inflammation research
Jin Y,Li Z,Wu Y,Li H,Liu Z,Liu L,Ouyang N,Zhou T,Fang B,Xia L
Thu Apr 28 00:00:00 UTC 2022
Phgdh serves a protective role in Il‑1β induced chondrocyte inflammation and oxidative‑stress damage.
Molecular medicine reports
Huang H,Liu K,Ou H,Qian X,Wan J
Tue Jun 01 00:00:00 UTC 2021
18β-Glycyrrhetinic acid inhibits IL-1β-induced inflammatory response in mouse chondrocytes and prevents osteoarthritic progression by activating Nrf2.
Food & function
Chen B,Zhu D,Xie C,Shi Y,Ni L,Zhang H,Li S,Lu J,Xiao J,Xia W,Huang C,Wang X
Mon Sep 20 00:00:00 UTC 2021
18β-Glycyrrhetinic acid inhibits IL-1β-induced inflammatory response in mouse chondrocytes and prevents osteoarthritic progression by activating Nrf2.
Food & function
Chen B,Zhu D,Xie C,Shi Y,Ni L,Zhang H,Li S,Lu J,Xiao J,Xia W,Huang C,Wang X
Mon Sep 20 00:00:00 UTC 2021
Physiological Reloading Recovers Histologically Disuse Atrophy of the Articular Cartilage and Bone by Hindlimb Suspension in Rat Knee Joint.
Cartilage
Takahashi I,Matsuzaki T,Kuroki H,Hoso M
Wed Dec 01 00:00:00 UTC 2021
Exogenous hydrogen sulfide inhibits apoptosis by regulating endoplasmic reticulum stress-autophagy axis and improves myocardial reconstruction after acute myocardial infarction.
Acta biochimica et biophysica Sinica
Li Y,Liu M,Yi J,Song X,Zheng X,Liu D,Wang S,Chu C,Yang J
Tue Dec 29 00:00:00 UTC 2020
Casticin Attenuates Osteoarthritis-Related Cartilage Degeneration by Inhibiting the ROS-Mediated NF-κB Signaling Pathway in vitro and in vivo.
Inflammation
Chu J,Yan B,Zhang J,Peng L,Ao X,Zheng Z,Jiang T,Zhang Z
Mon Jun 01 00:00:00 UTC 2020
Macromechanics and polycaprolactone fiber organization drive macrophage polarization and regulate inflammatory activation of tendon in vitro and in vivo.
Biomaterials
Schoenenberger AD,Tempfer H,Lehner C,Egloff J,Mauracher M,Bird A,Widmer J,Maniura-Weber K,Fucentese SF,Traweger A,Silvan U,Snedeker JG
Sat Aug 01 00:00:00 UTC 2020
Heparan sulfate deficiency leads to hypertrophic chondrocytes by increasing bone morphogenetic protein signaling.
Osteoarthritis and cartilage
Kawashima K,Ogawa H,Komura S,Ishihara T,Yamaguchi Y,Akiyama H,Matsumoto K
Sun Nov 01 00:00:00 UTC 2020
The protective effect of myricitrin in osteoarthritis: An in vitro and in vivo study.
International immunopharmacology
Yan Z,Lin Z,Wu Y,Zhan J,Qi W,Lin J,Shen J,Xue X,Pan X
Wed Jul 01 00:00:00 UTC 2020
OPN Deficiency Increases the Severity of Osteoarthritis Associated with Aberrant Chondrocyte Senescence and Apoptosis and Upregulates the Expression of Osteoarthritis-Associated Genes.
Pain research & management
Tian J,Cheng C,Kuang SD,Su C,Zhao X,Xiong YL,Li YS,Gao SG
Wed Mar 10 00:00:00 UTC 2021
Protective effect of resveratrol on obesity-related osteoarthritis via alleviating JAK2/STAT3 signaling pathway is independent of SOCS3.
Toxicology and applied pharmacology
Jiang M,He J,Gu H,Yang Y,Huang Y,Xu X,Liu L
Sat Feb 01 00:00:00 UTC 2020
Stachydrine ameliorates the progression of intervertebral disc degeneration via the PI3K/Akt/NF-κB signaling pathway: in vitro and in vivo studies.
Food & function
Shao Z,Lu J,Zhang C,Zeng G,Chen B,Liang H,Wu A,Zhang X,Wang X
Tue Dec 01 00:00:00 UTC 2020
Stachydrine ameliorates the progression of intervertebral disc degeneration via the PI3K/Akt/NF-κB signaling pathway: in vitro and in vivo studies.
Food & function
Shao Z,Lu J,Zhang C,Zeng G,Chen B,Liang H,Wu A,Zhang X,Wang X
Tue Dec 01 00:00:00 UTC 2020
Stachydrine ameliorates the progression of intervertebral disc degeneration via the PI3K/Akt/NF-κB signaling pathway: in vitro and in vivo studies.
Food & function
Shao Z,Lu J,Zhang C,Zeng G,Chen B,Liang H,Wu A,Zhang X,Wang X
Tue Dec 01 00:00:00 UTC 2020
Stachydrine ameliorates the progression of intervertebral disc degeneration via the PI3K/Akt/NF-κB signaling pathway: in vitro and in vivo studies.
Food & function
Shao Z,Lu J,Zhang C,Zeng G,Chen B,Liang H,Wu A,Zhang X,Wang X
Tue Dec 01 00:00:00 UTC 2020
Glycitin Suppresses Cartilage Destruction of Osteoarthritis in Mice.
Inflammation
Wang W,Yang R,Zhang M,Li J,Peng J,Xu M,Zhao Y,Li H,Pan X
Sat Aug 01 00:00:00 UTC 2020
S-allyl cysteine reduces osteoarthritis pathology in the tert-butyl hydroperoxide-treated chondrocytes and the destabilization of the medial meniscus model mice via the Nrf2 signaling pathway.
Aging
Shao Z,Pan Z,Lin J,Zhao Q,Wang Y,Ni L,Feng S,Tian N,Wu Y,Sun L,Gao W,Zhou Y,Zhang X,Wang X
Wed Oct 07 00:00:00 UTC 2020
Inhibition of PI3K/Akt/NF-κB signaling by Aloin for ameliorating the progression of osteoarthritis: In vitro and in vivo studies.
International immunopharmacology
Zhang C,Shao Z,Hu X,Chen Z,Li B,Jiang R,Bsoul N,Chen J,Xu C,Gao W
Tue Dec 01 00:00:00 UTC 2020
MicroRNA-675-3p regulates IL-1β-stimulated human chondrocyte apoptosis and cartilage degradation by targeting GNG5.
Biochemical and biophysical research communications
Shen XF,Cheng Y,Dong QR,Zheng MQ
Thu Jun 25 00:00:00 UTC 2020
IL-37 inhibits M1-like macrophage activation to ameliorate temporomandibular joint inflammation through the NLRP3 pathway.
Rheumatology (Oxford, England)
Luo P,Peng S,Yan Y,Ji P,Xu J
Thu Oct 01 00:00:00 UTC 2020
IL-37 inhibits M1-like macrophage activation to ameliorate temporomandibular joint inflammation through the NLRP3 pathway.
Rheumatology (Oxford, England)
Luo P,Peng S,Yan Y,Ji P,Xu J
Thu Oct 01 00:00:00 UTC 2020
Overexpression of MIG-6 in the cartilage induces an osteoarthritis-like phenotype in mice.
Arthritis research & therapy
Bellini M,Pest MA,Miranda-Rodrigues M,Qin L,Jeong JW,Beier F
Tue May 19 00:00:00 UTC 2020
Vitamin D3 protects articular cartilage by inhibiting the Wnt/β-catenin signaling pathway.
Experimental and therapeutic medicine
Yang T,Sun W,Duan YH,Sun YB,Ren YM,Hou WY,Tian MQ
Sat Aug 01 00:00:00 UTC 2020
Paclitaxel-induced peripheral neuropathy is caused by epidermal ROS and mitochondrial damage through conserved MMP-13 activation.
Scientific reports
Cirrincione AM,Pellegrini AD,Dominy JR,Benjamin ME,Utkina-Sosunova I,Lotti F,Jergova S,Sagen J,Rieger S
Wed Mar 04 00:00:00 UTC 2020
TLR4 contributes to the damage of cartilage and subchondral bone in discectomy-induced TMJOA mice.
Journal of cellular and molecular medicine
Liu X,Cai HX,Cao PY,Feng Y,Jiang HH,Liu L,Ke J,Long X
Thu Oct 01 00:00:00 UTC 2020
Hypoxic mast cells accelerate the proliferation, collagen accumulation and phenotypic alteration of human lung fibroblasts.
International journal of molecular medicine
Wang X,Lin L,Chai X,Wu Y,Li Y,Liu X
Wed Jan 01 00:00:00 UTC 2020
Hypoxic mast cells accelerate the proliferation, collagen accumulation and phenotypic alteration of human lung fibroblasts.
International journal of molecular medicine
Wang X,Lin L,Chai X,Wu Y,Li Y,Liu X
Wed Jan 01 00:00:00 UTC 2020
FTO promotes cell proliferation and migration in esophageal squamous cell carcinoma through up-regulation of MMP13.
Experimental cell research
Liu S,Huang M,Chen Z,Chen J,Chao Q,Yin X,Quan M
Wed Apr 01 00:00:00 UTC 2020
Oxymatrine suppresses IL-1β-induced degradation of the nucleus pulposus cell and extracellular matrix through the TLR4/NF-κB signaling pathway.
Experimental biology and medicine (Maywood, N.J.)
Wei K,Dai J,Wang Z,Pei Y,Chen Y,Ding Y,Ding Q,Ahati P,Zhou X,Wang H,Fang H
Sun Mar 01 00:00:00 UTC 2020
IκB kinase α: an independent prognostic factor that promotes the migration and invasion of oral squamous cell carcinoma.
The British journal of oral & maxillofacial surgery
Lv S,Wang F,Wang K,Fan Y,Xu J,Zheng J,Zeng Y
Wed Apr 01 00:00:00 UTC 2020
LncRNA TRPC7-AS1 regulates nucleus pulposus cellular senescence and ECM synthesis via competing with HPN for miR-4769-5p binding.
Mechanisms of ageing and development
Wang X,Li D,Wu H,Liu F,Liu F,Zhang Q,Li J
Tue Sep 01 00:00:00 UTC 2020
A chondroprotective effect of moracin on IL-1β-induced primary rat chondrocytes and an osteoarthritis rat model through Nrf2/HO-1 and NF-κB axes.
Food & function
Zhou S,Shi J,Wen H,Xie W,Han X,Li H
Wed Sep 23 00:00:00 UTC 2020
A chondroprotective effect of moracin on IL-1β-induced primary rat chondrocytes and an osteoarthritis rat model through Nrf2/HO-1 and NF-κB axes.
Food & function
Zhou S,Shi J,Wen H,Xie W,Han X,Li H
Wed Sep 23 00:00:00 UTC 2020
Punicalagin Inhibits Tert-Butyl Hydroperoxide-Induced Apoptosis and Extracellular Matrix Degradation in Chondrocytes by Activating Autophagy and Ameliorates Murine Osteoarthritis.
Drug design, development and therapy
Kong J,Wang J,Gong X,Zheng X,Chen T
Tue Sep 21 00:00:00 UTC 2021
Curcumol may reverse early and advanced liver fibrogenesis through downregulating the uPA/uPAR pathway.
Phytotherapy research : PTR
Li G,Lin J,Peng Y,Qin K,Wen L,Zhao T,Feng Q
Mon Jun 01 00:00:00 UTC 2020
MicroRNA-377-3p alleviates IL-1β-caused chondrocyte apoptosis and cartilage degradation in osteoarthritis in part by downregulating ITGA6.
Biochemical and biophysical research communications
Tu Y,Ma T,Wen T,Yang T,Xue L,Cai M,Wang F,Guan M,Xue H
Wed Feb 26 00:00:00 UTC 2020
MiR-455-3p reduces apoptosis and alleviates degeneration of chondrocyte through regulating PI3K/AKT pathway.
Life sciences
Wen X,Li H,Sun H,Zeng A,Lin R,Zhao J,Zhang Z
Wed Jul 15 00:00:00 UTC 2020
MiR-455-3p reduces apoptosis and alleviates degeneration of chondrocyte through regulating PI3K/AKT pathway.
Life sciences
Wen X,Li H,Sun H,Zeng A,Lin R,Zhao J,Zhang Z
Wed Jul 15 00:00:00 UTC 2020
MiR-455-3p reduces apoptosis and alleviates degeneration of chondrocyte through regulating PI3K/AKT pathway.
Life sciences
Wen X,Li H,Sun H,Zeng A,Lin R,Zhao J,Zhang Z
Wed Jul 15 00:00:00 UTC 2020
MiR-455-3p reduces apoptosis and alleviates degeneration of chondrocyte through regulating PI3K/AKT pathway.
Life sciences
Wen X,Li H,Sun H,Zeng A,Lin R,Zhao J,Zhang Z
Wed Jul 15 00:00:00 UTC 2020
miR-873-3p targets HDAC4 to stimulate matrix metalloproteinase-13 expression upon parathyroid hormone exposure in rat osteoblasts.
Journal of cellular physiology
Malavika D,Shreya S,Raj Priya V,Rohini M,He Z,Partridge NC,Selvamurugan N
Sun Nov 01 00:00:00 UTC 2020
Long non-coding RNA SNHG15 is a competing endogenous RNA of miR-141-3p that prevents osteoarthritis progression by upregulating BCL2L13 expression.
International immunopharmacology
Zhang X,Huang CR,Pan S,Pang Y,Chen YS,Zha GC,Guo KJ,Zheng X
Mon Jun 01 00:00:00 UTC 2020
Crenigacestat, a selective NOTCH1 inhibitor, reduces intrahepatic cholangiocarcinoma progression by blocking VEGFA/DLL4/MMP13 axis.
Cell death and differentiation
Mancarella S,Serino G,Dituri F,Cigliano A,Ribback S,Wang J,Chen X,Calvisi DF,Giannelli G
Sat Aug 01 00:00:00 UTC 2020
Reducing macrophage numbers alleviates temporomandibular joint ankylosis.
Cell and tissue research
Zhao L,Xiao E,He L,Duan D,He Y,Chen S,Zhang Y,Gan Y
Sun Mar 01 00:00:00 UTC 2020
Keratocytes promote corneal neovascularization through VEGFr3 induced by PPARα-inhibition.
Experimental eye research
Wang X,Tang L,Zhang Z,Li W,Chen Y
Wed Apr 01 00:00:00 UTC 2020
Targeting exosome-associated human antigen R attenuates fibrosis and inflammation in diabetic heart.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Govindappa PK,Patil M,Garikipati VNS,Verma SK,Saheera S,Narasimhan G,Zhu W,Kishore R,Zhang J,Krishnamurthy P
Sat Feb 01 00:00:00 UTC 2020
Effects of IL-1β on MMP-9 Expression in Cementoblast-Derived Cell Line and MMP-Mediated Degradation of Type I Collagen.
Inflammation
Du M,Wang Y,Liu Z,Wang L,Cao Z,Zhang C,Hao Y,He H
Mon Apr 01 00:00:00 UTC 2019
Effects of IL-1β on MMP-9 Expression in Cementoblast-Derived Cell Line and MMP-Mediated Degradation of Type I Collagen.
Inflammation
Du M,Wang Y,Liu Z,Wang L,Cao Z,Zhang C,Hao Y,He H
Mon Apr 01 00:00:00 UTC 2019
Quercetin alleviates rat osteoarthritis by inhibiting inflammation and apoptosis of chondrocytes, modulating synovial macrophages polarization to M2 macrophages.
Free radical biology & medicine
Hu Y,Gui Z,Zhou Y,Xia L,Lin K,Xu Y
Sun Dec 01 00:00:00 UTC 2019
Quercetin alleviates rat osteoarthritis by inhibiting inflammation and apoptosis of chondrocytes, modulating synovial macrophages polarization to M2 macrophages.
Free radical biology & medicine
Hu Y,Gui Z,Zhou Y,Xia L,Lin K,Xu Y
Sun Dec 01 00:00:00 UTC 2019
KLF2 Protects against Osteoarthritis by Repressing Oxidative Response through Activation of Nrf2/ARE Signaling In Vitro and In Vivo.
Oxidative medicine and cellular longevity
Gao X,Jiang S,Du Z,Ke A,Liang Q,Li X
Mon May 04 00:00:00 UTC 2020
KLF2 Protects against Osteoarthritis by Repressing Oxidative Response through Activation of Nrf2/ARE Signaling In Vitro and In Vivo.
Oxidative medicine and cellular longevity
Gao X,Jiang S,Du Z,Ke A,Liang Q,Li X
Mon May 04 00:00:00 UTC 2020
ZnO nanoparticles inhibit the activity of Porphyromonas gingivalis and Actinomyces naeslundii and promote the mineralization of the cementum.
BMC oral health
Wang J,Du L,Fu Y,Jiang P,Wang X
Tue May 14 00:00:00 UTC 2019
Alleviation of murine osteoarthritis by deletion of the focal adhesion mechanosensitive adapter, Hic-5.
Scientific reports
Miyauchi A,Kim-Kaneyama JR,Lei XF,Chang SH,Saito T,Haraguchi S,Miyazaki T,Miyazaki A
Thu Oct 31 00:00:00 UTC 2019
Effects of simvastatin on matrix metalloproteinase regulation in IL-1β-induced SW1353 cells.
Chemico-biological interactions
Cecen B,Keles D,Oktay G,Kozaci LD
Sun Sep 01 00:00:00 UTC 2019
Nobiletin Inhibits IL-1β-Induced Inflammation in Chondrocytes via Suppression of NF-κB Signaling and Attenuates Osteoarthritis in Mice.
Frontiers in pharmacology
Lin Z,Wu D,Huang L,Jiang C,Pan T,Kang X,Pan J
Tue Sep 29 00:00:00 UTC 2020
25-HC promotes hepatocellular carcinoma metastasis through up-regulation of TLR4 dependent FABP4.
American journal of cancer research
Wang S,Yao Y,Wang X,Zheng G,Ouyang W,Chen W
Tue Sep 29 00:00:00 UTC 2020
Adamts17 is involved in skeletogenesis through modulation of BMP-Smad1/5/8 pathway.
Cellular and molecular life sciences : CMLS
Oichi T,Taniguchi Y,Soma K,Oshima Y,Yano F,Mori Y,Chijimatsu R,Kim-Kaneyama JR,Tanaka S,Saito T
Sun Dec 01 00:00:00 UTC 2019
Targeting the IL-1β/IL-1Ra pathways for the aggregation of human islet amyloid polypeptide in an ex vivo organ culture system of the intervertebral disc.
Experimental & molecular medicine
Wu X,Liao Z,Wang K,Hua W,Liu X,Song Y,Zhang Y,Yang S,Yang C
Wed Sep 25 00:00:00 UTC 2019
Inhibition of Ihh Reverses Temporomandibular Joint Osteoarthritis via a PTH1R Signaling Dependent Mechanism.
International journal of molecular sciences
Yang H,Zhang M,Liu Q,Zhang H,Zhang J,Lu L,Xie M,Chen D,Wang M
Sat Aug 03 00:00:00 UTC 2019
Development of a Mouse Model of Knee Osteoarthritis Based on Obesity and Bipedal Walking.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society
Son KM,Jung HA,Hong JI,Park IY,Kim HA
Fri Nov 01 00:00:00 UTC 2019
Reduced PDGF-AA in subchondral bone leads to articular cartilage degeneration after strenuous running.
Journal of cellular physiology
Yao Z,Chen P,Wang S,Deng G,Hu Y,Lin Q,Zhang X,Yu B
Thu Aug 01 00:00:00 UTC 2019
Cortistatin binds to TNF-α receptors and protects against osteoarthritis.
EBioMedicine
Zhao Y,Li Y,Qu R,Chen X,Wang W,Qiu C,Liu B,Pan X,Liu L,Vasilev K,Hayball J,Dong S,Li W
Fri Mar 01 00:00:00 UTC 2019
A Compound of Chinese Herbs Protects against Alcoholic Liver Fibrosis in Rats via the TGF-β1/Smad Signaling Pathway.
Evidence-based complementary and alternative medicine : eCAM
Li X,Liu Y,Yue W,Tan Y,Wang H,Zhang L,Chen J
Thu Oct 01 00:00:00 UTC 2020
miR-100-5p-abundant exosomes derived from infrapatellar fat pad MSCs protect articular cartilage and ameliorate gait abnormalities via inhibition of mTOR in osteoarthritis.
Biomaterials
Wu J,Kuang L,Chen C,Yang J,Zeng WN,Li T,Chen H,Huang S,Fu Z,Li J,Liu R,Ni Z,Chen L,Yang L
Sat Jun 01 00:00:00 UTC 2019
miR-93-5p attenuates IL-1β-induced chondrocyte apoptosis and cartilage degradation in osteoarthritis partially by targeting TCF4.
Bone
Xue H,Tu Y,Ma T,Wen T,Yang T,Xue L,Cai M,Wang F,Guan M
Sat Jun 01 00:00:00 UTC 2019
25-HC decreases the sensitivity of human gastric cancer cells to 5-fluorouracil and promotes cells invasion via the TLR2/NF-κB signaling pathway.
International journal of oncology
Wang S,Yao Y,Rao C,Zheng G,Chen W
Fri Mar 01 00:00:00 UTC 2019
Toxoplasma gondii GRA15II effector-induced M1 cells ameliorate liver fibrosis in mice infected with Schistosomiasis japonica.
Cellular & molecular immunology
Xie Y,Wen H,Yan K,Wang S,Wang X,Chen J,Li Y,Xu Y,Zhong Z,Shen J,Chu D
Thu Feb 01 00:00:00 UTC 2018
Toxoplasma gondii GRA15II effector-induced M1 cells ameliorate liver fibrosis in mice infected with Schistosomiasis japonica.
Cellular & molecular immunology
Xie Y,Wen H,Yan K,Wang S,Wang X,Chen J,Li Y,Xu Y,Zhong Z,Shen J,Chu D
Thu Feb 01 00:00:00 UTC 2018
ETV4 transcription factor and MMP13 metalloprotease are interplaying actors of breast tumorigenesis.
Breast cancer research : BCR
Dumortier M,Ladam F,Damour I,Vacher S,Bièche I,Marchand N,de Launoit Y,Tulasne D,Chotteau-Lelièvre A
Wed Jul 11 00:00:00 UTC 2018
ETV4 transcription factor and MMP13 metalloprotease are interplaying actors of breast tumorigenesis.
Breast cancer research : BCR
Dumortier M,Ladam F,Damour I,Vacher S,Bièche I,Marchand N,de Launoit Y,Tulasne D,Chotteau-Lelièvre A
Wed Jul 11 00:00:00 UTC 2018
ETV4 transcription factor and MMP13 metalloprotease are interplaying actors of breast tumorigenesis.
Breast cancer research : BCR
Dumortier M,Ladam F,Damour I,Vacher S,Bièche I,Marchand N,de Launoit Y,Tulasne D,Chotteau-Lelièvre A
Wed Jul 11 00:00:00 UTC 2018
ETV4 transcription factor and MMP13 metalloprotease are interplaying actors of breast tumorigenesis.
Breast cancer research : BCR
Dumortier M,Ladam F,Damour I,Vacher S,Bièche I,Marchand N,de Launoit Y,Tulasne D,Chotteau-Lelièvre A
Wed Jul 11 00:00:00 UTC 2018
Postnatal deletion of Alk5 gene in meniscal cartilage accelerates age-dependent meniscal degeneration in mice.
Journal of cellular physiology
Wang Q,Tan Q,Xu W,Kuang L,Zhang B,Wang Z,Ni Z,Su N,Jin M,Li C,Jiang W,Huang J,Li F,Zhu Y,Chen H,Du X,Chen D,Deng C,Qi H,Xie Y,Chen L
Mon Jan 01 00:00:00 UTC 2018
Postnatal deletion of Alk5 gene in meniscal cartilage accelerates age-dependent meniscal degeneration in mice.
Journal of cellular physiology
Wang Q,Tan Q,Xu W,Kuang L,Zhang B,Wang Z,Ni Z,Su N,Jin M,Li C,Jiang W,Huang J,Li F,Zhu Y,Chen H,Du X,Chen D,Deng C,Qi H,Xie Y,Chen L
Mon Jan 01 00:00:00 UTC 2018
Emodin ameliorates cartilage degradation in osteoarthritis by inhibiting NF-κB and Wnt/β-catenin signaling in-vitro and in-vivo.
International immunopharmacology
Ding QH,Ye CY,Chen EM,Zhang W,Wang XH
Wed Aug 01 00:00:00 UTC 2018
Emodin ameliorates cartilage degradation in osteoarthritis by inhibiting NF-κB and Wnt/β-catenin signaling in-vitro and in-vivo.
International immunopharmacology
Ding QH,Ye CY,Chen EM,Zhang W,Wang XH
Wed Aug 01 00:00:00 UTC 2018
mTOR-mediated inactivation of 4E-BP1, an inhibitor of translation, precedes cartilage degeneration in rat osteoarthritic knees.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society
Katsara O,Kolupaeva V
Mon Oct 01 00:00:00 UTC 2018
mTOR-mediated inactivation of 4E-BP1, an inhibitor of translation, precedes cartilage degeneration in rat osteoarthritic knees.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society
Katsara O,Kolupaeva V
Mon Oct 01 00:00:00 UTC 2018
mTOR-mediated inactivation of 4E-BP1, an inhibitor of translation, precedes cartilage degeneration in rat osteoarthritic knees.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society
Katsara O,Kolupaeva V
Mon Oct 01 00:00:00 UTC 2018
SIRT3 Activation by Dihydromyricetin Suppresses Chondrocytes Degeneration via Maintaining Mitochondrial Homeostasis.
International journal of biological sciences
Wang J,Wang K,Huang C,Lin D,Zhou Y,Wu Y,Tian N,Fan P,Pan X,Xu D,Hu J,Zhou Y,Wang X,Zhang X
Mon Sep 09 00:00:00 UTC 2019
SIRT3 Activation by Dihydromyricetin Suppresses Chondrocytes Degeneration via Maintaining Mitochondrial Homeostasis.
International journal of biological sciences
Wang J,Wang K,Huang C,Lin D,Zhou Y,Wu Y,Tian N,Fan P,Pan X,Xu D,Hu J,Zhou Y,Wang X,Zhang X
Mon Sep 09 00:00:00 UTC 2019
Differential effects of high-physiological oestrogen on the degeneration of mandibular condylar cartilage and subchondral bone.
Bone
Ye T,Sun D,Mu T,Chu Y,Miao H,Zhang M,Yang H,Liu Q,Lu L,Xing X,Yu S
Fri Jun 01 00:00:00 UTC 2018
Differential effects of high-physiological oestrogen on the degeneration of mandibular condylar cartilage and subchondral bone.
Bone
Ye T,Sun D,Mu T,Chu Y,Miao H,Zhang M,Yang H,Liu Q,Lu L,Xing X,Yu S
Fri Jun 01 00:00:00 UTC 2018
Loss of Fgfr1 in chondrocytes inhibits osteoarthritis by promoting autophagic activity in temporomandibular joint.
The Journal of biological chemistry
Wang Z,Huang J,Zhou S,Luo F,Tan Q,Sun X,Ni Z,Chen H,Du X,Xie Y,Chen L
Fri Jun 08 00:00:00 UTC 2018
Cartilage-specific deletion of Alk5 gene results in a progressive osteoarthritis-like phenotype in mice.
Osteoarthritis and cartilage
Wang Q,Tan QY,Xu W,Qi HB,Chen D,Zhou S,Ni ZH,Kuang L,Guo JY,Huang JL,Wang XX,Wang ZQ,Su N,Chen L,Chen B,Jiang WL,Gao Y,Chen HG,Du XL,Xie YL,Chen L
Wed Nov 01 00:00:00 UTC 2017
Cartilage-specific deletion of Alk5 gene results in a progressive osteoarthritis-like phenotype in mice.
Osteoarthritis and cartilage
Wang Q,Tan QY,Xu W,Qi HB,Chen D,Zhou S,Ni ZH,Kuang L,Guo JY,Huang JL,Wang XX,Wang ZQ,Su N,Chen L,Chen B,Jiang WL,Gao Y,Chen HG,Du XL,Xie YL,Chen L
Wed Nov 01 00:00:00 UTC 2017
Cartilage-specific deletion of Alk5 gene results in a progressive osteoarthritis-like phenotype in mice.
Osteoarthritis and cartilage
Wang Q,Tan QY,Xu W,Qi HB,Chen D,Zhou S,Ni ZH,Kuang L,Guo JY,Huang JL,Wang XX,Wang ZQ,Su N,Chen L,Chen B,Jiang WL,Gao Y,Chen HG,Du XL,Xie YL,Chen L
Wed Nov 01 00:00:00 UTC 2017
Cartilage-specific deletion of Alk5 gene results in a progressive osteoarthritis-like phenotype in mice.
Osteoarthritis and cartilage
Wang Q,Tan QY,Xu W,Qi HB,Chen D,Zhou S,Ni ZH,Kuang L,Guo JY,Huang JL,Wang XX,Wang ZQ,Su N,Chen L,Chen B,Jiang WL,Gao Y,Chen HG,Du XL,Xie YL,Chen L
Wed Nov 01 00:00:00 UTC 2017
Upregulation of FBXW7 Suppresses Renal Cancer Metastasis and Epithelial Mesenchymal Transition.
Disease markers
Cai Y,Zhang M,Qiu X,Wang B,Fu Y,Zeng J,Bai J,Yang G
Fri Jun 22 00:00:00 UTC 2018
Upregulation of FBXW7 Suppresses Renal Cancer Metastasis and Epithelial Mesenchymal Transition.
Disease markers
Cai Y,Zhang M,Qiu X,Wang B,Fu Y,Zeng J,Bai J,Yang G
Fri Jun 22 00:00:00 UTC 2018
Chlorogenic acid prevents inflammatory responses in IL‑1β‑stimulated human SW‑1353 chondrocytes, a model for osteoarthritis.
Molecular medicine reports
Liu CC,Zhang Y,Dai BL,Ma YJ,Zhang Q,Wang Y,Yang H
Tue Aug 01 00:00:00 UTC 2017
Chlorogenic acid prevents inflammatory responses in IL‑1β‑stimulated human SW‑1353 chondrocytes, a model for osteoarthritis.
Molecular medicine reports
Liu CC,Zhang Y,Dai BL,Ma YJ,Zhang Q,Wang Y,Yang H
Tue Aug 01 00:00:00 UTC 2017
Icariin inhibits MMP‑1, MMP‑3 and MMP‑13 expression through MAPK pathways in IL‑1β‑stimulated SW1353 chondrosarcoma cells.
Molecular medicine reports
Zeng L,Rong XF,Li RH,Wu XY
Mon May 01 00:00:00 UTC 2017
Icariin inhibits MMP‑1, MMP‑3 and MMP‑13 expression through MAPK pathways in IL‑1β‑stimulated SW1353 chondrosarcoma cells.
Molecular medicine reports
Zeng L,Rong XF,Li RH,Wu XY
Mon May 01 00:00:00 UTC 2017
Potential Involvement of the IL-6/JAK/STAT3 Pathway in the Pathogenesis of Intervertebral Disc Degeneration.
Spine
Suzuki S,Fujita N,Fujii T,Watanabe K,Yagi M,Tsuji T,Ishii K,Miyamoto T,Horiuchi K,Nakamura M,Matsumoto M
Sat Jul 15 00:00:00 UTC 2017
Potential Involvement of the IL-6/JAK/STAT3 Pathway in the Pathogenesis of Intervertebral Disc Degeneration.
Spine
Suzuki S,Fujita N,Fujii T,Watanabe K,Yagi M,Tsuji T,Ishii K,Miyamoto T,Horiuchi K,Nakamura M,Matsumoto M
Sat Jul 15 00:00:00 UTC 2017
Chondroprotective Effects and Multitarget Mechanisms of Fu Yuan Capsule in a Rat Osteoarthritis Model.
Evidence-based complementary and alternative medicine : eCAM
Zeng L,Xiao CZ,Deng ZT,Li RH
Thu Oct 01 00:00:00 UTC 2020
Chondroprotective Effects and Multitarget Mechanisms of Fu Yuan Capsule in a Rat Osteoarthritis Model.
Evidence-based complementary and alternative medicine : eCAM
Zeng L,Xiao CZ,Deng ZT,Li RH
Thu Oct 01 00:00:00 UTC 2020
Simvastatin Inhibits IL-1β-Induced Apoptosis and Extracellular Matrix Degradation by Suppressing the NF-kB and MAPK Pathways in Nucleus Pulposus Cells.
Inflammation
Tu J,Li W,Zhang Y,Wu X,Song Y,Kang L,Liu W,Wang K,Li S,Hua W,Yang C
Thu Jun 01 00:00:00 UTC 2017
AMPK deficiency in chondrocytes accelerated the progression of instability-induced and ageing-associated osteoarthritis in adult mice.
Scientific reports
Zhou S,Lu W,Chen L,Ge Q,Chen D,Xu Z,Shi D,Dai J,Li J,Ju H,Cao Y,Qin J,Chen S,Teng H,Jiang Q
Wed Feb 22 00:00:00 UTC 2017
AMPK deficiency in chondrocytes accelerated the progression of instability-induced and ageing-associated osteoarthritis in adult mice.
Scientific reports
Zhou S,Lu W,Chen L,Ge Q,Chen D,Xu Z,Shi D,Dai J,Li J,Ju H,Cao Y,Qin J,Chen S,Teng H,Jiang Q
Wed Feb 22 00:00:00 UTC 2017
Tumor-derived exosomes educate dendritic cells to promote tumor metastasis via HSP72/HSP105-TLR2/TLR4 pathway.
Oncoimmunology
Shen Y,Guo D,Weng L,Wang S,Ma Z,Yang Y,Wang P,Wang J,Cai Z
Tue Jan 12 00:00:00 UTC 2021
Tumor-derived exosomes educate dendritic cells to promote tumor metastasis via HSP72/HSP105-TLR2/TLR4 pathway.
Oncoimmunology
Shen Y,Guo D,Weng L,Wang S,Ma Z,Yang Y,Wang P,Wang J,Cai Z
Tue Jan 12 00:00:00 UTC 2021
Conditional knockdown of hyaluronidase 2 in articular cartilage stimulates osteoarthritic progression in a mice model.
Scientific reports
Higuchi Y,Nishida Y,Kozawa E,Zhuo L,Arai E,Hamada S,Morita D,Ikuta K,Kimata K,Ushida T,Ishiguro N
Tue Aug 01 00:00:00 UTC 2017
Conditional knockdown of hyaluronidase 2 in articular cartilage stimulates osteoarthritic progression in a mice model.
Scientific reports
Higuchi Y,Nishida Y,Kozawa E,Zhuo L,Arai E,Hamada S,Morita D,Ikuta K,Kimata K,Ushida T,Ishiguro N
Tue Aug 01 00:00:00 UTC 2017
Conditional knockout of tissue factor pathway inhibitor 2 in vascular endothelial cells accelerates atherosclerotic plaque development in mice.
Thrombosis research
Hong J,Liu R,Chen L,Wu B,Yu J,Gao W,Pan J,Luo X,Shi H
Fri Jan 01 00:00:00 UTC 2016
Conditional knockout of tissue factor pathway inhibitor 2 in vascular endothelial cells accelerates atherosclerotic plaque development in mice.
Thrombosis research
Hong J,Liu R,Chen L,Wu B,Yu J,Gao W,Pan J,Luo X,Shi H
Fri Jan 01 00:00:00 UTC 2016
Exogenous fibroblast growth factor 9 attenuates cartilage degradation and aggravates osteophyte formation in post-traumatic osteoarthritis.
Osteoarthritis and cartilage
Zhou S,Wang Z,Tang J,Li W,Huang J,Xu W,Luo F,Xu M,Wang J,Wen X,Chen L,Chen H,Su N,Shen Y,Du X,Xie Y,Chen L
Thu Dec 01 00:00:00 UTC 2016
Exogenous fibroblast growth factor 9 attenuates cartilage degradation and aggravates osteophyte formation in post-traumatic osteoarthritis.
Osteoarthritis and cartilage
Zhou S,Wang Z,Tang J,Li W,Huang J,Xu W,Luo F,Xu M,Wang J,Wen X,Chen L,Chen H,Su N,Shen Y,Du X,Xie Y,Chen L
Thu Dec 01 00:00:00 UTC 2016
Conditional Deletion of Fgfr3 in Chondrocytes leads to Osteoarthritis-like Defects in Temporomandibular Joint of Adult Mice.
Scientific reports
Zhou S,Xie Y,Li W,Huang J,Wang Z,Tang J,Xu W,Sun X,Tan Q,Huang S,Luo F,Xu M,Wang J,Wu T,Chen L,Chen H,Su N,Du X,Shen Y,Chen L
Mon Apr 04 00:00:00 UTC 2016
Conditional Deletion of Fgfr3 in Chondrocytes leads to Osteoarthritis-like Defects in Temporomandibular Joint of Adult Mice.
Scientific reports
Zhou S,Xie Y,Li W,Huang J,Wang Z,Tang J,Xu W,Sun X,Tan Q,Huang S,Luo F,Xu M,Wang J,Wu T,Chen L,Chen H,Su N,Du X,Shen Y,Chen L
Mon Apr 04 00:00:00 UTC 2016
Iron overload in a murine model of hereditary hemochromatosis is associated with accelerated progression of osteoarthritis under mechanical stress.
Osteoarthritis and cartilage
Camacho A,Simão M,Ea HK,Cohen-Solal M,Richette P,Branco J,Cancela ML
Tue Mar 01 00:00:00 UTC 2016
Fibroblast Growth Factor Receptor 3 Inhibits Osteoarthritis Progression in the Knee Joints of Adult Mice.
Arthritis & rheumatology (Hoboken, N.J.)
Tang J,Su N,Zhou S,Xie Y,Huang J,Wen X,Wang Z,Wang Q,Xu W,Du X,Chen H,Chen L
Sat Oct 01 00:00:00 UTC 2016
Deletion of Panx3 Prevents the Development of Surgically Induced Osteoarthritis.
Journal of molecular medicine (Berlin, Germany)
Moon PM,Penuela S,Barr K,Khan S,Pin CL,Welch I,Attur M,Abramson SB,Laird DW,Beier F
Sat Aug 01 00:00:00 UTC 2015
Deletion of Panx3 Prevents the Development of Surgically Induced Osteoarthritis.
Journal of molecular medicine (Berlin, Germany)
Moon PM,Penuela S,Barr K,Khan S,Pin CL,Welch I,Attur M,Abramson SB,Laird DW,Beier F
Sat Aug 01 00:00:00 UTC 2015
17β-estradiol protects against apoptosis induced by interleukin-1β in rat nucleus pulposus cells by down-regulating MMP-3 and MMP-13.
Apoptosis : an international journal on programmed cell death
Yang SD,Yang DL,Sun YP,Wang BL,Ma L,Feng SQ,Ding WY
Sun Mar 01 00:00:00 UTC 2015
17β-estradiol protects against apoptosis induced by interleukin-1β in rat nucleus pulposus cells by down-regulating MMP-3 and MMP-13.
Apoptosis : an international journal on programmed cell death
Yang SD,Yang DL,Sun YP,Wang BL,Ma L,Feng SQ,Ding WY
Sun Mar 01 00:00:00 UTC 2015
Potent effects of dioscin against liver fibrosis.
Scientific reports
Zhang X,Han X,Yin L,Xu L,Qi Y,Xu Y,Sun H,Lin Y,Liu K,Peng J
Wed Apr 08 00:00:00 UTC 2015
Potent effects of dioscin against liver fibrosis.
Scientific reports
Zhang X,Han X,Yin L,Xu L,Qi Y,Xu Y,Sun H,Lin Y,Liu K,Peng J
Wed Apr 08 00:00:00 UTC 2015
Deletion of Dual Specificity Phosphatase 1 Does Not Predispose Mice to Increased Spontaneous Osteoarthritis.
PloS one
Pest MA,Pest CA,Bellini MR,Feng Q,Beier F
Wed Jul 06 00:00:00 UTC 2016
Deletion of Dual Specificity Phosphatase 1 Does Not Predispose Mice to Increased Spontaneous Osteoarthritis.
PloS one
Pest MA,Pest CA,Bellini MR,Feng Q,Beier F
Wed Jul 06 00:00:00 UTC 2016
Levofloxacin increases apoptosis of rat annulus fibrosus cells via the mechanism of upregulating MMP-2 and MMP-13.
International journal of clinical and experimental medicine
Wei HK,Yang SD,Bai ZL,Zhang X,Yang DL,Ding WY
Wed Feb 17 00:00:00 UTC 2016
Levofloxacin increases apoptosis of rat annulus fibrosus cells via the mechanism of upregulating MMP-2 and MMP-13.
International journal of clinical and experimental medicine
Wei HK,Yang SD,Bai ZL,Zhang X,Yang DL,Ding WY
Wed Feb 17 00:00:00 UTC 2016
Loss of Vhl in cartilage accelerated the progression of age-associated and surgically induced murine osteoarthritis.
Osteoarthritis and cartilage
Weng T,Xie Y,Yi L,Huang J,Luo F,Du X,Chen L,Liu C,Chen D,Chen L
Fri Aug 01 00:00:00 UTC 2014
Loss of Vhl in cartilage accelerated the progression of age-associated and surgically induced murine osteoarthritis.
Osteoarthritis and cartilage
Weng T,Xie Y,Yi L,Huang J,Luo F,Du X,Chen L,Liu C,Chen D,Chen L
Fri Aug 01 00:00:00 UTC 2014
Chondroprotective effects and multi-target mechanisms of Icariin in IL-1 beta-induced human SW 1353 chondrosarcoma cells and a rat osteoarthritis model.
International immunopharmacology
Zeng L,Wang W,Rong XF,Zhong Y,Jia P,Zhou GQ,Li RH
Wed Jan 01 00:00:00 UTC 2014
Chondroprotective effects and multi-target mechanisms of Icariin in IL-1 beta-induced human SW 1353 chondrosarcoma cells and a rat osteoarthritis model.
International immunopharmacology
Zeng L,Wang W,Rong XF,Zhong Y,Jia P,Zhou GQ,Li RH
Wed Jan 01 00:00:00 UTC 2014
Keratocytes create stromal spaces to promote corneal neovascularization via MMP13 expression.
Investigative ophthalmology & visual science
Ma J,Zhou D,Fan M,Wang H,Huang C,Zhang Z,Wu Y,Li W,Chen Y,Liu Z
Thu Sep 04 00:00:00 UTC 2014
Keratocytes create stromal spaces to promote corneal neovascularization via MMP13 expression.
Investigative ophthalmology & visual science
Ma J,Zhou D,Fan M,Wang H,Huang C,Zhang Z,Wu Y,Li W,Chen Y,Liu Z
Thu Sep 04 00:00:00 UTC 2014
Keratocytes create stromal spaces to promote corneal neovascularization via MMP13 expression.
Investigative ophthalmology & visual science
Ma J,Zhou D,Fan M,Wang H,Huang C,Zhang Z,Wu Y,Li W,Chen Y,Liu Z
Thu Sep 04 00:00:00 UTC 2014
Keratocytes create stromal spaces to promote corneal neovascularization via MMP13 expression.
Investigative ophthalmology & visual science
Ma J,Zhou D,Fan M,Wang H,Huang C,Zhang Z,Wu Y,Li W,Chen Y,Liu Z
Thu Sep 04 00:00:00 UTC 2014
Protective effects of biochanin A on articular cartilage: in vitro and in vivo studies.
BMC complementary and alternative medicine
Wu DQ,Zhong HM,Ding QH,Ba L
Sat Nov 15 00:00:00 UTC 2014
Protective effects of biochanin A on articular cartilage: in vitro and in vivo studies.
BMC complementary and alternative medicine
Wu DQ,Zhong HM,Ding QH,Ba L
Sat Nov 15 00:00:00 UTC 2014
Anti-arthritic effects of crocin in interleukin-1β-treated articular chondrocytes and cartilage in a rabbit osteoarthritic model.
Inflammation research : official journal of the European Histamine Research Society ... [et al.]
Ding Q,Zhong H,Qi Y,Cheng Y,Li W,Yan S,Wang X
Tue Jan 01 00:00:00 UTC 2013
Anti-arthritic effects of crocin in interleukin-1β-treated articular chondrocytes and cartilage in a rabbit osteoarthritic model.
Inflammation research : official journal of the European Histamine Research Society ... [et al.]
Ding Q,Zhong H,Qi Y,Cheng Y,Li W,Yan S,Wang X
Tue Jan 01 00:00:00 UTC 2013
Celastrol, an inhibitor of heat shock protein 90β potently suppresses the expression of matrix metalloproteinases, inducible nitric oxide synthase and cyclooxygenase-2 in primary human osteoarthritic chondrocytes.
European journal of pharmacology
Ding QH,Cheng Y,Chen WP,Zhong HM,Wang XH
Wed May 15 00:00:00 UTC 2013
Celastrol, an inhibitor of heat shock protein 90β potently suppresses the expression of matrix metalloproteinases, inducible nitric oxide synthase and cyclooxygenase-2 in primary human osteoarthritic chondrocytes.
European journal of pharmacology
Ding QH,Cheng Y,Chen WP,Zhong HM,Wang XH
Wed May 15 00:00:00 UTC 2013
Suppression of hyaluronan synthesis alleviates inflammatory responses in murine arthritis and in human rheumatoid synovial fibroblasts.
Arthritis and rheumatism
Yoshioka Y,Kozawa E,Urakawa H,Arai E,Futamura N,Zhuo L,Kimata K,Ishiguro N,Nishida Y
Wed May 01 00:00:00 UTC 2013
Suppression of hyaluronan synthesis alleviates inflammatory responses in murine arthritis and in human rheumatoid synovial fibroblasts.
Arthritis and rheumatism
Yoshioka Y,Kozawa E,Urakawa H,Arai E,Futamura N,Zhuo L,Kimata K,Ishiguro N,Nishida Y
Wed May 01 00:00:00 UTC 2013
Genetic inhibition of fibroblast growth factor receptor 1 in knee cartilage attenuates the degeneration of articular cartilage in adult mice.
Arthritis and rheumatism
Weng T,Yi L,Huang J,Luo F,Wen X,Du X,Chen Q,Deng C,Chen D,Chen L
Sat Dec 01 00:00:00 UTC 2012
Genetic inhibition of fibroblast growth factor receptor 1 in knee cartilage attenuates the degeneration of articular cartilage in adult mice.
Arthritis and rheumatism
Weng T,Yi L,Huang J,Luo F,Wen X,Du X,Chen Q,Deng C,Chen D,Chen L
Sat Dec 01 00:00:00 UTC 2012
Genetic inhibition of fibroblast growth factor receptor 1 in knee cartilage attenuates the degeneration of articular cartilage in adult mice.
Arthritis and rheumatism
Weng T,Yi L,Huang J,Luo F,Wen X,Du X,Chen Q,Deng C,Chen D,Chen L
Sat Dec 01 00:00:00 UTC 2012
Genetic inhibition of fibroblast growth factor receptor 1 in knee cartilage attenuates the degeneration of articular cartilage in adult mice.
Arthritis and rheumatism
Weng T,Yi L,Huang J,Luo F,Wen X,Du X,Chen Q,Deng C,Chen D,Chen L
Sat Dec 01 00:00:00 UTC 2012
Drug delivery from internally implanted biomedical devices used in traumatology and in orthopedic surgery.
Expert opinion on drug delivery
Arruebo M,Vilaboa N,Santamaria J
Sat May 01 00:00:00 UTC 2010
