Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
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Recommended positive controls: HeLa.
Predicted reactivity: Mouse (91%), Rat (91%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The protein encoded by this gene is considered a member of the membrane-type MMP (MT-MMP) subfamily. However, this protein is unique among the MT-MMP's in that it is a GPI-anchored protein rather than a transmembrane protein. The protein activates MMP-2 by cleavage.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: matrix metallo protease; matrix metallopeptidase 17 (membrane-inserted); matrix metalloproteinase 17 (membrane-inserted); Matrix metalloproteinase-17; Membrane-type matrix metalloproteinase 4; Membrane-type-4 matrix metalloproteinase; MMP; MMP-17; MMPs; MT-MMP 4; MT4-MMP
Gene Aliases: MMP-17; MMP17; MT4-MMP; MT4MMP; MTMMP4
UniProt ID: (Human) Q9ULZ9
Entrez Gene ID: (Human) 4326
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