MMP20 degrades amelogenin, the major protein component of the enamel matrix, as well as two of the macromolecules characterizing the cartilage extracellular matrix: aggrecan and the cartilage oligomeric matrix protein (COMP). MMP20 may play a central role in tooth enamel formation.
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Protein Aliases: Enamel metalloproteinase; Enamelysin; matrix metallo protease; matrix metallopeptidase 20 (enamelysin); matrix metalloproteinase 20 (enamelysin); Matrix metalloproteinase-20; MMP; MMP-20; MMPs
Gene Aliases: AI2A2; MMP-20; MMP20