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Invitrogen
MMP7 Polyclonal Antibody
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FIGURE: 1 / 1
MMP7 Antibody (PA5-77791) in WB
Western blot analysis of MMP7 in rat kidney lysate using 10 µg of protein. Sample was prepared with 5% milk and TBST, incubated with MMP7 polyclonal antibody (Product # PA5-77791) using a dilution of 1:1000 (2 hours at RT) and followed by a Goat Anti-Rabbit HRP secondary antibody. Samples are arranged as follows: Lane 1: molecular weight ladder, Lane 2: rat kidney lysate.
Product Details
PA5-77791
Applications
Tested Dilution
Publications
Product Specifications
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide from the C-terminal of Human MMP7 (257-267 aa), conjugated to Keyhole Limpet Haemocyanin (KLH)
Conjugate
Form
Liquid
Concentration
1 mg/mL
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
Product Specific Information
A 1:1,000 dilution of PA5-77791 was sufficient for detection of MMP7 in 10 µg of rat kidney cell lysates by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.|Detects 29.7 kDa.
Target Information
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades proteoglycans, fibronectin, elastin and casein and differs from most MMP family members in that it lacks a conserved C-terminal protein domain. The enzyme is involved in wound healing, and studies in mice suggest that it regulates the activity of defensins in intestinal mucosa. The gene is part of a cluster of MMP genes which localize to chromosome 11q22. 3.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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