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Invitrogen
MMP7 Monoclonal Antibody (ID2)
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FIGURE: 1 / 1
MMP7 Antibody (MA5-14215) in IHC
Biomedicines 2021 -
Figure 1 Representative examples of immunohistochemical staining for MMP-7, MMP-14 and TIMP-1 in colonic mucosa of patients depending on the group of study. 100x magnification for ( a - c , g - l , p - r ). 200x magnification for ( d - f , m - o ). The counterstaining was made with hematoxylin. Arrows indicate cell types: red, cancer cells; blue, epithelial cells; green, mononuclear inflammatory cells; and ... View More
Product Details
MA5-14215
Applications
Tested Dilution
Publications
Product Specifications
Published species
Human,
Rat,
Sheep
Host/Isotype
Mouse
/ IgG2b, kappa
Class
Monoclonal
Type
Antibody
Clone
ID2
Immunogen
Recombinant human matrilysin (PUMP-1)
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Amount
100 µg
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
MA5-14215 targets MMP-7 (Matrilysin) in IF applications and shows reactivity with Human samples.
The MA5-14215 immunogen is recombinant human matrilysin (PUMP-1).
Target Information
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades proteoglycans, fibronectin, elastin and casein and differs from most MMP family members in that it lacks a conserved C-terminal protein domain. The enzyme is involved in wound healing, and studies in mice suggest that it regulates the activity of defensins in intestinal mucosa. The gene is part of a cluster of MMP genes which localize to chromosome 11q22. 3.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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