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Proteintech
MNT Polyclonal Antibody
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Product Details
23742-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
MNT Fusion Protein Ag20666 (233-582 aa encoded by BC117563)
Conjugate
Form
Liquid
Concentration
0.31 mg/mL
Amount
46.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: RAHLKECFE TLKRNIPNVD DKKTSNLSVL RTALRYIQSL KRKEKEYEHE MERLAREKIA TQQRLAELKH ELSQWMDVLE IDRVLRQTGQ PEDDQASTST ASEGEDNIDE DMEEDRAGLG PPKLSHRPQP ELLKSTLPPP STTPAPLPPH PHPHPHSVAL PPAHLPVQQQ QPQQKTPLPA PPPPPAAPAQ TLVPAPAHLV ATAGGGSTVI AHTATTHASV IQTVNHVLQG PGGKHIAHIA PSAPSPAVQL APATPPIGHI TVHPATLNHV AHLGSQLPLY PQPVAVSHIA HTLSHQQVNG TAGLGPPATV MAKPAVGAQV VHHPQLVGQT VLNPVTMVTM PSFPVSTLKL A (233-582 aa encoded by BC117563)
Target Information
The Myc/Max/Mad network comprises a group of transcription factors that co-interact to regulate gene-specific transcriptional activation or repression. This gene encodes a protein member of the Myc/Max/Mad network. This protein has a basic-Helix-Loop-Helix-zipper domain (bHLHzip) with which it binds the canonical DNA sequence CANNTG, known as the E box, following heterodimerization with Max proteins. This protein is likely a transcriptional repressor and an antagonist of Myc-dependent transcriptional activation and cell growth. This protein represses transcription by binding to DNA binding proteins at its N-terminal Sin3-interaction domain.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: bHLHd3; Class D basic helix-loop-helix protein 3; MAX binding protein; Max-binding protein MNT; Max-interacting protein; MNT, MAX dimerization protein; Myc antagonist MNT; Protein ROX; unnamed protein product
Gene Aliases: BHLHD3; lncRNA-HAL; MAD6; MNT; MXD6; ROX
UniProt ID: (Human) Q99583
Entrez Gene ID: (Human) 4335
RNA polymerase II regulatory region sequence-specific DNA binding
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding
DNA binding
chromatin binding
transcription factor activity, sequence-specific DNA binding
protein binding
identical protein binding
protein dimerization activity
negative regulation of transcription from RNA polymerase II promoter
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
regulation of cell cycle
cellular senescence
negative regulation of apoptotic signaling pathway
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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