The protein encoded by this gene is a component of the Hippo signaling pathway, which controls organ size and tumor growth by enhancing apoptosis. Loss of the encoded protein results in cell proliferation and cancer formation. The encoded protein is also involved in the control of microtubule stability during cytokinesis. Several transcript variants encoding different isoforms have been found for this gene.
Protein Aliases: MOB kinase activator 1A; Mob1 alpha; Mob1 homolog 1B; MOB1 Mps One Binder homolog A; MOB1, Mps One Binder kinase activator-like 1B; Mob1A; Mps one binder kinase activator-like 1B
Gene Aliases: 4022402H07Rik; C2orf6; MATS1; MOB1; MOB1A; MOB4B; MOBK1B; MOBKL1B