Proteintech

MOF Polyclonal Antibody

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MOF Antibody in Western Blot (WB) — Rat liver tissue were subjected to SDS PAGE followed by western blot with 13842-1-AP (MOF Antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours.

MOF Antibody in Immunoprecipitation (IP) — IP result of anti-MOF (IP:13842-1-AP, 4ug; Detection:13842-1-AP 1:600) with HeLa cells lysate 1200ug.

Product Details

13842-1-AP

Applications	Tested Dilution	Publications
Western Blot (WB)	1:500-1:2,000	View 3 publications 3 publications
Immunoprecipitation (IP)	0.5-4.0 µg	-

Product Specifications
Species Reactivity	Human, Mouse, Rat
Published species	Human, Mouse
Host/Isotype	Rabbit / IgG
Class	Polyclonal
Type	Antibody
Immunogen	MOF Fusion Protein Ag4802 (118-467 aa encoded by BC037773)
Conjugate	Unconjugated
Form	Liquid
Concentration	0.19 mg/mL
Purification	Antigen affinity chromatography
Storage buffer	PBS, pH 7.3, with 50% glycerol
Contains	0.02% sodium azide
Storage conditions	-20°C

Product Specific Information

Immunogen sequence: AVQKNSEKY LSELAEQPER KITRNQKRKH DEINHVQKTY AEMDPTTAAL EKEHEAITKV KYVDKIHIGN YEIDAWYFSP FPEDYGKQPK LWLCEYCLKY MKYEKSYRFH LGQCQWRQPP GKEIYRKSNI SVYEVDGKDH KIYCQNLCLL AKLFLDHKTL YFDVEPFVFY ILTEVDRQGA HIVGYFSKEK ESPDGNNVAC ILTLPPYQRR GYGKFLIAFS YELSKLESTV GSPEKPLSDL GKLSYRSYWS WVLLEILRDF RGTLSIKDLS QMTSITQNDI ISTLQSLNMV KYWKGQHVIC VTPKLVEEHL KSAQYKKPPI TGGWGAAVCR GRWGSVSMWT GRSQGLLIAV T (118-467 aa encoded by BC037773)

Target Information

The MYST family of histone acetyltransferases, which includes MYST1, is named for the founding members MOZ (MYST3), yeast YBF2 and SAS2, and TIP60 (HTATIP). All members of this family contain a MYST region of about 240 amino acids with a canonical acetyl-CoA-binding site and a C2HC-type zinc finger motif. Most MYST proteins also have a chromodomain involved in protein-protein interactions and targeting transcriptional regulators to chromatin.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Histone Acetyltransferase Mof Affects the Progression of DSS-Induced Colitis.

Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology

Yang Y,Guan J,Shaikh AS,Liang Y,Sun L,Wang M,Li D,Qiu C,Li X

Fri Aug 17 00:00:00 EDT 2018

Acetylproteomic analysis reveals functional implications of lysine acetylation in human spermatozoa (sperm).

Molecular & cellular proteomics : MCP

Yu H,Diao H,Wang C,Lin Y,Yu F,Lu H,Xu W,Li Z,Shi H,Zhao S,Zhou Y,Zhang Y

Wed Apr 01 00:00:00 EDT 2015

Regulation of acetylation restores proteolytic function of diseased myocardium in mouse and human.

Molecular & cellular proteomics : MCP

Wang D,Fang C,Zong NC,Liem DA,Cadeiras M,Scruggs SB,Yu H,Kim AK,Yang P,Deng M,Lu H,Ping P

Sun Dec 01 00:00:00 EST 2013

Bioinformatics

Protein Aliases: h FLJ14040; Histone acetyltransferase KAT8; histone acetyltransferase MYST1; K(lysine) acetyltransferase 8; Lysine acetyltransferase 8; MOZ, YBF2/SAS3, SAS2 and TIP60 protein 1; MYST histone acetyltransferase 1; MYST protein 1; MYST-1; ortholog of Drosophila males absent on the first (MOF); probable histone acetyltransferase MYST1

Gene Aliases: 2010203C02Rik; 5830450F21Rik; D7Ertd629e; hMOF; KAT8; MOF; MYST1; PP7073; ZC2HC8

UniProt ID: (Human) Q9H7Z6, (Mouse) Q9D1P2, (Rat) Q5XI06

Entrez Gene ID: (Human) 84148, (Mouse) 67773, (Rat) 310194

Molecular Function: histone modifying enzyme