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Invitrogen
MPG Polyclonal Antibody
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FIGURE: 1 / 4
MPG Antibody (PA5-102764) in IHC (P)
Immunohistochemistry analysis of MPG in mouse brain tissue. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. Samples were incubated with MPG polyclonal antibody (Product # PA5-102764) using a dilution of 1:100 (4°C overnight) followed by HRP conjugated anti-Rabbit secondary antibody.
Product Details
PA5-102764
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human MPG(Accession P29372), corresponding to amino acid residues L117-C167.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total MPG.
Target Information
MPG functions in the hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine, and 7-methylguanine from the damaged DNA polymer formed by alkylation lesions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 3' end of the Mid1 gene, localized 68 kb upstream the humanzeta globin gene on 16p; 3-alkyladenine DNA glycosylase; 3-methyladenine DNA glycosidase; 3-methyladenine DNA glycosylase; ADPG; alkylpurine-DNA-N-glycosylase; anpg; CRA36.1 (3-methyl-adenine DNA glycosylase); DNA-3-methyladenine glycosylase; N-methylpurine-DNA glycocylase; N-methylpurine-DNA glycosylase; N-methylpurine-DNA glycosylase, MPG; PIG11; proliferation-inducing protein 11; proliferation-inducing protein 16
Gene Aliases: 9830006D05; AAG; ADPG; AI326268; ANPG; APNG; CRA36.1; MDG; MID1; MPG; PIG11; PIG16
UniProt ID: (Human) P29372, (Mouse) Q04841
Entrez Gene ID: (Human) 4350, (Rat) 24561, (Mouse) 268395
DNA binding
damaged DNA binding
catalytic activity
alkylbase DNA N-glycosylase activity
protein binding
hydrolase activity
DNA N-glycosylase activity
DNA-3-methyladenine glycosylase activity
DNA-7-methylguanine glycosylase activity
DNA-7-methyladenine glycosylase activity
DNA-3-methylguanine glycosylase activity
DNA metabolism protein
DNA glycosylase
nucleic acid metabolism protein
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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