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Product Details
PA5-96313
| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
1:500-1:2,000 | - |
Immunocytochemistry (ICC/IF) |
1:50 - 1:100 | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Human, Mouse |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-293 of human MPG. |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
0.32 mg/mL |
Purification |
Affinity Chromatography |
Storage buffer |
PBS, pH 7.3, with 50% glycerol |
Contains |
0.02% sodium azide |
Storage conditions |
-20° C, Avoid Freeze/Thaw Cycles |
RRID |
AB_2808115 |
Product Specific Information
Immunogen sequence: MPARSGAQFC RRMGQKKQRP ARAGQPHSSS DAAQAPAEQP HSSSDAAQAP CPRERCLGPP TTPGPYRSIY FSSPKGHLTR LGLEFFDQPA VPLARAFLGQ VLVRRLPNGT ELRGRIVETE AYLGPEDEAA HSRGGRQTPR NRGMFMKPGT LYVYIIYGMY FCMNISSQGD GACVLLRALE PLEGLETMRQ LRSTLRKGTA SRVLKDRELC SGPSKLCQAL AINKSFDQRD LAQDEAVWLE RGPLEPSEPA VVAAARVGVG HAGEWARKPL RFYVRGSPWV SVVDRVAEQD TQA; Positive Samples: MCF7, K-562, U-937, Mouse liver; Cellular Location: Cytoplasm, Mitochondrion matrix, Nucleus, mitochondrion nucleoid
Target Information
MPG functions in the hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine, and 7-methylguanine from the damaged DNA polymer formed by alkylation lesions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 3' end of the Mid1 gene, localized 68 kb upstream the humanzeta globin gene on 16p; 3-alkyladenine DNA glycosylase; 3-methyladenine DNA glycosidase; 3-methyladenine DNA glycosylase; ADPG; alkylpurine-DNA-N-glycosylase; CRA36.1 (3-methyl-adenine DNA glycosylase); DNA-3-methyladenine glycosylase; N-methylpurine-DNA glycosylase; N-methylpurine-DNA glycosylase, MPG; proliferation-inducing protein 11; proliferation-inducing protein 16
Gene Aliases: 9830006D05; AAG; ADPG; AI326268; ANPG; APNG; CRA36.1; MDG; MID1; MPG; PIG11; PIG16
UniProt ID: (Human) P29372, (Mouse) Q04841
Entrez Gene ID: (Human) 4350, (Mouse) 268395
Molecular Function:
DNA metabolism protein
DNA glycosylase
nucleic acid metabolism protein
damaged DNA binding
alkylbase DNA N-glycosylase activity
protein binding
DNA-3-methyladenine glycosylase activity
DNA N-glycosylase activity
DNA-7-methylguanine glycosylase activity
DNA-7-methyladenine glycosylase activity
DNA-3-methylguanine glycosylase activity
DNA binding
catalytic activity
hydrolase activity
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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