MPHOSPH9 Polyclonal Antibody, MaxPab™

Product Specific Information

Product may be used with Western Blot (Transfected lysate).

The Isotype of this product is composed of an IgG Mixture.

Immunogen sequence: MGFFSLSSER NESVIHYPES TEPEIQQEMS TSQPDCNVDS CSVSSGYGTF CISELNLYKS KDPKEFMEHI DVPKGQYVAP AVPAESLVDG VKNENFYIQT PEECHVSLKE DVSISPGEFE HNFLGENKVS EVYSGKTNSN AITSWAQKLK QNQPKRAHVE DGGSRSKQGN EQSKKTPIEK SDFAAATHPR AFYLSKPDET PNAWMSDSGT GLTYWKLEEK DMHHSLPETL EKTFISLSST DVSPNQSNTS NEMKLPSLKD IYYKKQRENK QLPERNLTSA SNPNHPPEVL TLDPTLHMKP KQQISGIQPH GLPNALDDRI SFSPDSVLEP SMSSPSDIDS FSQASNVTSQ LPGFPKYPSH TKASPVDSWK NQTFQNESRT SSTFPSVYTI TSNDISVNTV DEENTVMVAS ASVSQSQLPG TANSVPECIS LTSLEDPVIL SKIRQNLKEK HARHIADLRA YYESEINSLK QKLEAKEISG VEDWKITNQI LVDRCGQLDS ALHEATSRVR TLENKNNLLE IEVNDLRERF SAASSASKIL QERIEEMRTS SKEKDNTIIR LKSRLQDLEE AFENAYKLSD DKEAQLKQEN KMFQDLLGEY ESLGKEHRRV KDALNTTENK LLDAYTQISD LKRMISKLEA QVKQVEHENM LSLRHNSRIH VRPSRANTLA TSDVSRRKWL IPGAEYSIFT GQPLDTQDSN VDNQLEETCS LGHRSPLEKD SSPGSSSTSL LIKKQRETSD TPIMRALKEL DEGKIFKNWG TQTEKEDTSN INPRQTETSV NASRSPEKCA QQRQKRLNSA SQRSSSLPPS NRKSSTPTKR EIMLTPVTVA YSPKRSPKEN LSPGFSHLLS KNESSPIRFD ILLDDLDTVP VSTLQRTNPR KQLQFLPLDD SEEKTYSEKA TDNHVNHSSC PEPVPNGVKK VSVRTAWEKN KSVSYEQCKP VSVTPQGNDF EYTAKIRTLA ETERFFDELT KEKDQIEAAL SRMPSPGGRI TLQTRLNQEA LEDRLERINR ELGSVRMTLK KFHVLRTSAN L

Target Information

Progression of cells from interphase to mitosis involves alterations in cell structures and activities. The transition from G2 to M phase is induced by M phase-promoting factor (MPF). In M phase, many proteins are phosphorylated directly by MPF or indirectly by kinases activated by MPF. These M phase phosphoproteins (MPPs), also known as MPHOSPHs, permit disassembly of interphase structures and generation of M phase enzymatic activities and structures. MPP9 (M-phase phosphoprotein 9), also known as MPHOSPH9, is a 1,031 amino acid peripheral membrane protein of the Golgi apparatus that exists as two alternatively spliced isoforms. The gene encoding MPP9 maps to human chromosome 12, which encodes over 1,100 genes and comprises approximately 4.5% of the human genome. Chromosome 12 is associated with a variety of diseases and afflictions, including hypochondrogenesis, achondrogenesis, Kniest dysplasia, Noonan syndrome and trisomy 12p.