This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated. View Details
Immunogen sequence: AVSLLDGGLR HWLRQNLPLS SGKSQPAPAE FRAQLDPAFI KTYEDIKENL ESRRFQVVDS RATGRFRGTE PEPRDGIEPG HIPGTVNIPF TDFLSQEGLE KSPEEIRHLF QEKKVDLSKP LVATCGSGVT ACHVALGAYL CGKPD
Highest antigen sequence identity to the following orthologs: Mouse - 81%, Rat - 82%.
This protein encoded by this gene catalyzes the transfer of a sulfur ion from 3-mercaptopyruvate to cyanide or other thiol compounds. It may be involved in cysteine degradation and cyanide detoxification. There is confusion in literature between this protein (mercaptopyruvate sulfurtransferase, MPST), which appears to be cytoplasmic, and thiosulfate sulfurtransferase (rhodanese, TST, GeneID:7263), which is a mitochondrial protein. Deficiency in MPST activity has been implicated in a rare inheritable disorder known as mercaptolactate-cysteine disulfiduria (MCDU). Alternatively spliced transcript variants encoding same or different isoforms have been identified for this gene.
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Protein Aliases: 3-mercaptopyruvate sulfurtransferase; human liver rhodanese; MST; testicular tissue protein Li 200; tRNA thiouridin modification protein 1; TST2
Gene Aliases: MPST; MST; TST2; TUM1
UniProt ID: (Human) P25325
Entrez Gene ID: (Human) 4357