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Proteintech
MRGPRD Polyclonal Antibody
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Product Details
23640-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
MRGPRD fusion protein Ag20316
Conjugate
Form
Liquid
Concentration
0.85 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: FLICSLPLSI YWFVLYWLSL PPEMQVLCFS LSRLSSSVSS SANPVIYFLV GSRRSHRLPT RSLGTVLQQA LREEPELEGG ETPTVGTNEM GA
Target Information
May regulate nociceptor function and/or development, including the sensation or modulation of pain. Functions as a specific membrane receptor for beta-alanine. Beta-alanine at micromolar doses specifically evoked Ca(2+) influx in cells expressing the receptor. Beta-alanine decreases forskolin-stimulated cAMP production in cells expressing the receptor, suggesting that the receptor couples with G-protein G(q) and G(i). Localized at the plasma membrane but internalized into the cytoplasm after treatment with beta-alanine.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Beta-alanine receptor; G protein-coupled receptor MrgD; G-protein coupled receptor TGR7; mas-related G protein-coupled MRGD; Mas-related G protein-coupled receptor d; Mas-related G-protein coupled receptor member D; MAS-related G-protein coupled receptor, member D; MAS-related gene D; MAS-related GPR, member D; MRGD G protein-coupled receptor
Gene Aliases: Gm499; Mgrd; MRGD; MRGPRD; TGR7
UniProt ID: (Human) Q8TDS7, (Rat) Q7TN41, (Mouse) Q91ZB8
Entrez Gene ID: (Human) 116512, (Rat) 293648, (Mouse) 211578
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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