The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. The specific function of this protein has not yet been determined; however, this protein may play a role in the transport of biliary and intestinal excretion of organic anions. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized.
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Protein Aliases: ATP-binding cassette sub-family C member 3; ATP-binding cassette, sub-family C (CFTR/MRP), member 3; Canalicular multispecific organic anion transporter 2; canicular multispecific organic anion transporter; DKFZp686E22157; MLP-2; MOAT-D; MRP-like protein 2; Multi-specific organic anion transporter D; multidrug resistance associated protein; multidrug resistance protein 3; Multidrug resistance-associated protein 3; organic anion transporter
Gene Aliases: ABC31; ABCC3; CMOAT2; EST90757; MLP2; MOAT-D; MRP3