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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant protein fragment corresponding to a region within amino acids 58 and 230 of Human MRPL10|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 20% glycerol|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:500-1:3000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA5-31244 targets MRPL10 in IHC (P) and WB applications and shows reactivity with Human samples.
The PA5-31244 immunogen is recombinant protein fragment corresponding to a region within amino acids 58 and 230 of Human MRPL10.
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. A pseudogene corresponding to this gene is found on chromosome 5q.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
39S ribosomal protein L10; 39S ribosomal protein L10, mitochondrial; 39S ribosomal protein L8; 39S ribosomal protein L8, mitochondrial; L10MT; L8mt; mitochondrial; MRP-L10; MRP-L8; MRPL8; RPML8
L10MT; MRP-L10; MRP-L8; MRPL10; MRPL8; RPML8